NO20002005L - FremgangsmÕte for behandling av hyperkoagulable tilstander eller protein C mangel - Google Patents

FremgangsmÕte for behandling av hyperkoagulable tilstander eller protein C mangel

Info

Publication number
NO20002005L
NO20002005L NO20002005A NO20002005A NO20002005L NO 20002005 L NO20002005 L NO 20002005L NO 20002005 A NO20002005 A NO 20002005A NO 20002005 A NO20002005 A NO 20002005A NO 20002005 L NO20002005 L NO 20002005L
Authority
NO
Norway
Prior art keywords
treatment
protein
deficiency
procedure
apc
Prior art date
Application number
NO20002005A
Other languages
English (en)
Other versions
NO20002005D0 (no
Inventor
Brian William Grinnell
Daniel Lawrence Hartman
Sau-Chi Betty Yan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO20002005D0 publication Critical patent/NO20002005D0/no
Publication of NO20002005L publication Critical patent/NO20002005L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4866Protein C (3.4.21.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6464Protein C (3.4.21.69)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Surgery (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20002005A 1997-10-20 2000-04-17 FremgangsmÕte for behandling av hyperkoagulable tilstander eller protein C mangel NO20002005L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6254997P 1997-10-20 1997-10-20
US6476597P 1997-11-07 1997-11-07
PCT/US1998/021723 WO1999020293A1 (en) 1997-10-20 1998-10-14 Methods for treating hypercoagulable states or acquired protein c deficiency

Publications (2)

Publication Number Publication Date
NO20002005D0 NO20002005D0 (no) 2000-04-17
NO20002005L true NO20002005L (no) 2000-05-16

Family

ID=26742406

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002005A NO20002005L (no) 1997-10-20 2000-04-17 FremgangsmÕte for behandling av hyperkoagulable tilstander eller protein C mangel

Country Status (27)

Country Link
US (7) US6037322A (no)
EP (2) EP0913156B1 (no)
JP (2) JP3805981B2 (no)
KR (1) KR100798174B1 (no)
CN (1) CN1276726A (no)
AT (1) ATE292979T1 (no)
AU (1) AU748417B2 (no)
BR (1) BR9812965A (no)
CA (1) CA2306983A1 (no)
DE (1) DE69829721T2 (no)
DK (1) DK0913156T3 (no)
EA (1) EA002496B1 (no)
ES (1) ES2239382T3 (no)
HU (2) HUP0001237A3 (no)
ID (1) ID24901A (no)
IL (2) IL135712A0 (no)
MY (1) MY117655A (no)
NO (1) NO20002005L (no)
NZ (1) NZ504026A (no)
PL (1) PL200515B1 (no)
PT (1) PT913156E (no)
SI (1) SI0913156T1 (no)
TR (1) TR200001059T2 (no)
TW (1) TWI225404B (no)
UA (1) UA72194C2 (no)
WO (1) WO1999020293A1 (no)
ZA (1) ZA989385B (no)

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US20030220259A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of neurological disorders
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US20080318871A1 (en) * 2001-12-21 2008-12-25 Khan Nisar A Treatment of neurological disorders
US20040013661A1 (en) * 2001-12-21 2004-01-22 Gert Wensvoort Stratification
US20030220257A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of trauma
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JP4846799B2 (ja) 2005-07-05 2011-12-28 バイオテンプト ベー.フェー. 腫瘍の治療
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GR1005700B (el) * 2006-09-01 2007-10-22 (40%) ����� �������� Τροπος αντιμετωπισης της 1ης φασης του εγκαυματοσσε μη σηπτικους ασθενεις με συνεχη ενδοφλεβια χορηγηση ενεργοποιημενης πρωτεινης-c για 48 ωρες με στοχο τη μειωση της τελικης εγκαυματικης βλαβης καιαυξηση της ταχυτητας επουλωσης κατα τα πρωτα επτα μετεγκαυματικα 24ωρα
US20100284997A1 (en) * 2006-10-31 2010-11-11 Griffin John H Dosing regimen of activated protein c and variants having reduced anticoagulant activity
RU2445365C1 (ru) * 2010-11-03 2012-03-20 Общество с ограниченной ответственностью "Инновационный Центр "Новые Технологии и Материалы" (ООО "ИЦ Новтехмат") Штамм гибридных культивируемых клеток mus musculus - продуцент моноклональных антител, специфичных к протеину с человека (варианты)
RU2490722C1 (ru) * 2012-04-24 2013-08-20 Федеральное государственное бюджетное учреждение науки Институт химической биологии и фундаментальной медицины Сибирского отделения Российской академии наук (ИХБФМ СО РАН) Способ восстановления кровотока в регионе тромбированной вены в эксперименте
ES2676422T3 (es) 2012-07-04 2018-07-19 Zz Biotech Llc Proteína C activada para su uso en el tratamiento de trastornos inflamatorios de la piel
ES2890675T3 (es) 2014-04-16 2022-01-21 Zz Biotech Llc APC para uso en el tratamiento de cicatrices cutáneas anormales
PT3131572T (pt) 2014-04-16 2021-09-24 Zz Biotech Llc Análogo de apc para utilização em cicatrização de feridas
US11098387B2 (en) 2018-06-15 2021-08-24 Ab Sandvik Materials Technology Duplex stainless steel strip and method for producing thereof

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Also Published As

Publication number Publication date
CA2306983A1 (en) 1999-04-29
MY117655A (en) 2004-07-31
HUP0001237A2 (hu) 2000-08-28
AU9804098A (en) 1999-05-10
US20010036456A1 (en) 2001-11-01
US6268337B1 (en) 2001-07-31
PL340096A1 (en) 2001-01-15
HUP0100025A3 (en) 2003-08-28
EA200000445A1 (ru) 2000-10-30
IL135712A0 (en) 2001-05-20
IL135712A (en) 2010-12-30
BR9812965A (pt) 2001-03-20
UA72194C2 (en) 2005-02-15
KR20010031217A (ko) 2001-04-16
NO20002005D0 (no) 2000-04-17
NZ504026A (en) 2002-12-20
KR100798174B1 (ko) 2008-01-24
HK1020529A1 (en) 2000-05-12
EP0913156A1 (en) 1999-05-06
EP0913156B1 (en) 2005-04-13
ZA989385B (en) 2000-04-14
JP2005097313A (ja) 2005-04-14
US6156734A (en) 2000-12-05
US6037322A (en) 2000-03-14
US6268344B1 (en) 2001-07-31
HU224901B1 (en) 2006-04-28
US6008199A (en) 1999-12-28
ID24901A (id) 2000-08-31
DK0913156T3 (da) 2005-06-27
EP1449537A3 (en) 2005-09-21
CN1276726A (zh) 2000-12-13
HUP0001237A3 (en) 2002-01-28
SI0913156T1 (en) 2005-10-31
ATE292979T1 (de) 2005-04-15
JP2001520199A (ja) 2001-10-30
PT913156E (pt) 2005-08-31
WO1999020293A1 (en) 1999-04-29
TWI225404B (en) 2004-12-21
AU748417B2 (en) 2002-06-06
TR200001059T2 (tr) 2000-10-23
PL200515B1 (pl) 2009-01-30
ES2239382T3 (es) 2005-09-16
DE69829721D1 (de) 2005-05-19
EP1449537A2 (en) 2004-08-25
US6426071B2 (en) 2002-07-30
JP3805981B2 (ja) 2006-08-09
EA002496B1 (ru) 2002-06-27
US6489296B1 (en) 2002-12-03
DE69829721T2 (de) 2006-02-09
HUP0100025A2 (hu) 2001-05-28

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