ZA971525B - Tropane derivatives, their preparation and use. - Google Patents

Tropane derivatives, their preparation and use.

Info

Publication number
ZA971525B
ZA971525B ZA9701525A ZA971525A ZA971525B ZA 971525 B ZA971525 B ZA 971525B ZA 9701525 A ZA9701525 A ZA 9701525A ZA 971525 A ZA971525 A ZA 971525A ZA 971525 B ZA971525 B ZA 971525B
Authority
ZA
South Africa
Prior art keywords
disorders
derivatives
preparation
monoamine neurotransmitter
uptake
Prior art date
Application number
ZA9701525A
Other languages
English (en)
Inventor
Jorgen Scheel-Kruger
Peter Moldt
Frank Watjen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of ZA971525B publication Critical patent/ZA971525B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9701525A 1996-02-22 1997-02-21 Tropane derivatives, their preparation and use. ZA971525B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK19496 1996-02-22

Publications (1)

Publication Number Publication Date
ZA971525B true ZA971525B (en) 1997-10-21

Family

ID=8090830

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9701525A ZA971525B (en) 1996-02-22 1997-02-21 Tropane derivatives, their preparation and use.

Country Status (32)

Country Link
US (3) US6288079B1 (ja)
EP (2) EP0885220B1 (ja)
JP (1) JP3238414B2 (ja)
KR (1) KR100446571B1 (ja)
CN (1) CN1077574C (ja)
AT (1) ATE203023T1 (ja)
AU (1) AU720358B2 (ja)
BG (1) BG63945B1 (ja)
BR (1) BR9707636A (ja)
CA (1) CA2244773C (ja)
CZ (1) CZ287007B6 (ja)
DE (1) DE69705608T2 (ja)
DK (1) DK0885220T3 (ja)
EE (1) EE04751B1 (ja)
ES (1) ES2159839T3 (ja)
GR (1) GR3036829T3 (ja)
HK (1) HK1018957A1 (ja)
HU (1) HU228356B1 (ja)
IL (1) IL125146A (ja)
IS (1) IS1824B (ja)
NO (1) NO318731B1 (ja)
NZ (1) NZ330886A (ja)
PL (1) PL185132B1 (ja)
PT (1) PT885220E (ja)
RU (1) RU2167876C2 (ja)
SG (1) SG99853A1 (ja)
SI (1) SI0885220T1 (ja)
SK (1) SK281813B6 (ja)
TR (1) TR199801641T2 (ja)
UA (1) UA49872C2 (ja)
WO (1) WO1997030997A1 (ja)
ZA (1) ZA971525B (ja)

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Also Published As

Publication number Publication date
GR3036829T3 (en) 2002-01-31
ATE203023T1 (de) 2001-07-15
PT885220E (pt) 2001-11-30
AU1794097A (en) 1997-09-10
CN1211982A (zh) 1999-03-24
DE69705608T2 (de) 2002-05-16
NO983877L (no) 1998-08-21
JP2000504739A (ja) 2000-04-18
EE9800254A (et) 1999-02-15
IL125146A0 (en) 1999-01-26
RU2167876C2 (ru) 2001-05-27
TR199801641T2 (xx) 1998-11-23
US6288079B1 (en) 2001-09-11
SK92998A3 (en) 1998-11-04
CA2244773C (en) 2006-01-03
AU720358B2 (en) 2000-06-01
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KR100446571B1 (ko) 2004-11-03
IL125146A (en) 2002-03-10
SG99853A1 (en) 2003-11-27
PL328503A1 (en) 1999-02-01
WO1997030997A1 (en) 1997-08-28
KR19990087127A (ko) 1999-12-15
HU228356B1 (en) 2013-03-28
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DE69705608D1 (de) 2001-08-16
JP3238414B2 (ja) 2001-12-17
HUP9901199A3 (en) 2001-02-28
BG102637A (en) 1999-06-30
SI0885220T1 (en) 2001-12-31
US20010018444A1 (en) 2001-08-30
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BR9707636A (pt) 1999-07-27
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IS4825A (is) 1998-08-17
UA49872C2 (uk) 2002-10-15
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