ATE345135T1 - Tropan-derivate mit dopamin-wiederaufnahme-hemmer-wirkung für die behandlung von ischämischen erkrankungen - Google Patents
Tropan-derivate mit dopamin-wiederaufnahme-hemmer-wirkung für die behandlung von ischämischen erkrankungenInfo
- Publication number
- ATE345135T1 ATE345135T1 AT02803752T AT02803752T ATE345135T1 AT E345135 T1 ATE345135 T1 AT E345135T1 AT 02803752 T AT02803752 T AT 02803752T AT 02803752 T AT02803752 T AT 02803752T AT E345135 T1 ATE345135 T1 AT E345135T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- dopamine
- rupup
- ischemic diseases
- tropane derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200101781 | 2001-11-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE345135T1 true ATE345135T1 (de) | 2006-12-15 |
Family
ID=8160868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02803752T ATE345135T1 (de) | 2001-11-30 | 2002-11-28 | Tropan-derivate mit dopamin-wiederaufnahme-hemmer-wirkung für die behandlung von ischämischen erkrankungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US7381733B2 (de) |
EP (1) | EP1453511B1 (de) |
JP (1) | JP2005511639A (de) |
AT (1) | ATE345135T1 (de) |
AU (1) | AU2002365288A1 (de) |
DE (1) | DE60216142T2 (de) |
WO (1) | WO2003045388A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003099783A2 (en) * | 2002-03-28 | 2003-12-04 | President And Fellows Of Harvard College | Tropane compounds |
EP1594874A1 (de) * | 2003-02-12 | 2005-11-16 | Neurosearch A/S | Neue 8-aza-bicyclo[3.2.1]oktanderivate und deren verwendung als monoaminneurotransmitterwiederaufnahmeinhibitoren |
AR045141A1 (es) * | 2003-07-31 | 2005-10-19 | Neurosearch As | Sales de tartrato de 2- metoximetil-3-(3,4-diclorofenil)-8-azabiciclo (3,2,1) octano. composiciones farmaceuticas que los contienen y usos de las mismas. |
CA2545513C (en) * | 2003-11-18 | 2013-01-08 | Boehringer Ingelheim International Gmbh | Solid pharmaceutical preparation form |
DE102004004965B4 (de) * | 2004-01-31 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung eines 2-(Ethoxymethyl)-tropanderivates |
CA2614833A1 (en) * | 2005-07-12 | 2007-01-18 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising 2, 3-disubstituted tropanes for the treatment of disorders of sexual desire |
GB0703998D0 (en) * | 2007-03-01 | 2007-04-11 | Glaxo Group Ltd | Novel salt |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179567A (en) * | 1978-04-10 | 1979-12-18 | Sterling Drug Inc. | 2-Aryltropane compounds |
US5272160A (en) * | 1989-05-17 | 1993-12-21 | Pfizer Inc | 2-piperidino-1-alkanol derivatives as antiischemic agents |
US6329520B1 (en) * | 1990-08-09 | 2001-12-11 | Research Triangle Institute | Cocaine receptor binding ligands |
US5128118A (en) * | 1990-08-09 | 1992-07-07 | Research Triangle Institute | Cocaine receptor binding ligands |
AU671163B2 (en) | 1992-12-23 | 1996-08-15 | Neurosearch A/S | Alkyl substituted heterocyclic compounds |
AU672052B2 (en) | 1992-12-23 | 1996-09-19 | Neurosearch A/S | Antidepressant and antiparkinsonian compounds |
DK154192D0 (da) * | 1992-12-23 | 1992-12-23 | Neurosearch As | Heterocycliske forbindelser |
AU672644B2 (en) | 1992-12-23 | 1996-10-10 | Neurosearch A/S | Aryl substituted heterocyclic compounds |
CZ284379B6 (cs) * | 1994-04-19 | 1998-11-11 | Neurosearch A/S | Tropanové deriváty, způsob jejich přípravy a jejich použití |
RU2139857C1 (ru) * | 1994-08-18 | 1999-10-20 | Пфайзер Инк. | Производные 3-(пиперидинил-1)-хроман-4,7-диола и 1-(4-гидроксифенил)-2-(пиперидинил-1)-алканола, фармацевтическая композиция и способ связывания nmda рецептора |
US6241963B1 (en) * | 1995-10-19 | 2001-06-05 | The Trustees Of The University Of Pennsylvania | Dopamine and serotonin transporter ligands and imaging agents |
WO1997016451A1 (en) * | 1995-11-02 | 1997-05-09 | Neurosearch A/S | Fused tropane-derivatives as neurotransmitter reuptake inhibitors |
JP3238414B2 (ja) | 1996-02-22 | 2001-12-17 | ニューロサーチ・アクティーゼルスカブ | トロパン―誘導体、その製造方法及びその使用方法 |
AU7847800A (en) | 1999-10-15 | 2001-04-30 | Mayo Foundation For Medical Education And Research | Topical anesthetics useful for treating cancer, autoimmune diseases and ischemia |
EP1361874A1 (de) | 2001-02-15 | 2003-11-19 | Neurosearch A/S | Behandlung von durch übermässigen oder unzureichendem zelltod gekennzeichneten erkrankungen |
-
2002
- 2002-11-28 WO PCT/DK2002/000796 patent/WO2003045388A1/en active IP Right Grant
- 2002-11-28 DE DE60216142T patent/DE60216142T2/de not_active Expired - Lifetime
- 2002-11-28 US US10/494,922 patent/US7381733B2/en not_active Expired - Fee Related
- 2002-11-28 AU AU2002365288A patent/AU2002365288A1/en not_active Abandoned
- 2002-11-28 EP EP02803752A patent/EP1453511B1/de not_active Expired - Lifetime
- 2002-11-28 JP JP2003546890A patent/JP2005511639A/ja active Pending
- 2002-11-28 AT AT02803752T patent/ATE345135T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US7381733B2 (en) | 2008-06-03 |
US20050020621A1 (en) | 2005-01-27 |
DE60216142T2 (de) | 2007-09-06 |
EP1453511A1 (de) | 2004-09-08 |
AU2002365288A1 (en) | 2003-06-10 |
DE60216142D1 (de) | 2006-12-28 |
JP2005511639A (ja) | 2005-04-28 |
WO2003045388A1 (en) | 2003-06-05 |
EP1453511B1 (de) | 2006-11-15 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |