MX2021008208A - Tesofensina para la reduccion del peso corporal para pacientes con sindrome de prader-willi. - Google Patents
Tesofensina para la reduccion del peso corporal para pacientes con sindrome de prader-willi.Info
- Publication number
- MX2021008208A MX2021008208A MX2021008208A MX2021008208A MX2021008208A MX 2021008208 A MX2021008208 A MX 2021008208A MX 2021008208 A MX2021008208 A MX 2021008208A MX 2021008208 A MX2021008208 A MX 2021008208A MX 2021008208 A MX2021008208 A MX 2021008208A
- Authority
- MX
- Mexico
- Prior art keywords
- tesofensine
- prader
- body weight
- reduction
- willi
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se relaciona con un método de reducción del peso corporal o hiperfagia en pacientes con síndrome de Prader-Willi que comprende administrar el compuesto activo Tesofensina o una sal farmacéuticamente aceptable del mismo, preferiblemente por la administración de una formulación de liberación controlada que comprende los compuestos activos de tesofensina y un bloqueador delta. La invención se relaciona además con composiciones farmacéuticas que comprenden más de 0.150 mg de Tesofensina o una sal farmacéuticamente aceptable de la misma y no más de 25 mg de Metoprolol.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA3029052A CA3029052A1 (en) | 2019-01-07 | 2019-01-07 | Tesofensine for reduction of body weight in prader-willi patients |
CA3058933A CA3058933A1 (en) | 2019-10-16 | 2019-10-16 | Tesofensine for reduction of body weight in prader-willi patients |
PCT/EP2020/050153 WO2020144146A1 (en) | 2019-01-07 | 2020-01-07 | Tesofensine for reduction of body weight in prader-willi patients |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2021008208A true MX2021008208A (es) | 2021-11-17 |
Family
ID=69165342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2021008208A MX2021008208A (es) | 2019-01-07 | 2020-01-07 | Tesofensina para la reduccion del peso corporal para pacientes con sindrome de prader-willi. |
Country Status (4)
Country | Link |
---|---|
US (1) | US20220160658A1 (es) |
BR (1) | BR112021013463A2 (es) |
MX (1) | MX2021008208A (es) |
WO (1) | WO2020144146A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115884790A (zh) * | 2020-01-10 | 2023-03-31 | 康圣博施医药有限公司 | 药物的治疗组合以及其使用方法 |
MX2022013236A (es) * | 2020-04-22 | 2023-01-24 | Saniona As | Tratamiento de la obesidad hipotalamica. |
WO2023161533A1 (en) * | 2022-02-28 | 2023-08-31 | Noema Pharma Ag | Triple uptake inhibitor for the treatment of atypical depression |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA971525B (en) | 1996-02-22 | 1997-10-21 | Neurosearch As | Tropane derivatives, their preparation and use. |
US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
AU2003282375A1 (en) | 2003-02-05 | 2004-08-30 | Ipca Laboratories Limited | Pharmaceutical compositions and process of production thereof |
DE102005034351A1 (de) | 2005-07-22 | 2007-01-25 | Sension, Biologische Detektions- Und Schnelltestsysteme Gmbh | Farb-Umschlag-Indikator zur Statusanzeige von RFID-Tickets und -Etiketten |
US20070053983A1 (en) | 2005-09-06 | 2007-03-08 | Girish Jain | Extended release compositions of metoprolol succinate |
US20070092573A1 (en) | 2005-10-24 | 2007-04-26 | Laxminarayan Joshi | Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist |
WO2007110753A2 (en) | 2006-03-28 | 2007-10-04 | Wockhardt Ltd | Extended release dosage forms of metoprolol |
CA2657202A1 (en) | 2006-07-28 | 2008-01-31 | Farmaprojects, S.A. | Extended release pharmaceutical formulation of metoprolol and process for its preparation |
US8235632B2 (en) | 2010-05-14 | 2012-08-07 | Illinois Tool Works Inc. | Cargo bag valve deflector |
WO2012052834A2 (en) | 2010-10-21 | 2012-04-26 | Inventia Healthcare Private Limited | Multiple unit particulate system comprising metoprolol succinate |
EP2747757A1 (en) | 2011-08-26 | 2014-07-02 | Wockhardt Limited | Methods for treating cardiovascular disorders |
CN104114163A (zh) | 2011-12-09 | 2014-10-22 | 沃克哈特有限公司 | 治疗心血管疾病的方法 |
CN108853071A (zh) | 2012-02-16 | 2018-11-23 | 萨尼奥纳有限责任公司 | 用于联合治疗的药物组合物 |
US20160143864A1 (en) | 2013-07-09 | 2016-05-26 | Sun Pharmaceutical Industries Limited | Extended-release pharmaceutical compositions of metoprolol |
EA033298B1 (ru) * | 2015-03-03 | 2019-09-30 | Саниона А/С | Комбинированная лекарственная форма тезофензина и метопролола |
-
2020
- 2020-01-07 WO PCT/EP2020/050153 patent/WO2020144146A1/en active Application Filing
- 2020-01-07 MX MX2021008208A patent/MX2021008208A/es unknown
- 2020-01-07 BR BR112021013463-8A patent/BR112021013463A2/pt not_active Application Discontinuation
- 2020-01-07 US US17/420,181 patent/US20220160658A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
BR112021013463A2 (pt) | 2021-09-14 |
US20220160658A1 (en) | 2022-05-26 |
WO2020144146A1 (en) | 2020-07-16 |
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