HK1018957A1 - Tropane-derivatives, their preparation and use - Google Patents

Tropane-derivatives, their preparation and use

Info

Publication number
HK1018957A1
HK1018957A1 HK99104015A HK99104015A HK1018957A1 HK 1018957 A1 HK1018957 A1 HK 1018957A1 HK 99104015 A HK99104015 A HK 99104015A HK 99104015 A HK99104015 A HK 99104015A HK 1018957 A1 HK1018957 A1 HK 1018957A1
Authority
HK
Hong Kong
Prior art keywords
disorders
derivatives
tropane
monoamine neurotransmitter
uptake
Prior art date
Application number
HK99104015A
Other languages
English (en)
Inventor
Jorgen Scheel-Kruger
Peter Moldt
Frank Watjen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of HK1018957A1 publication Critical patent/HK1018957A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK99104015A 1996-02-22 1999-09-17 Tropane-derivatives, their preparation and use HK1018957A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK19496 1996-02-22
PCT/EP1997/000850 WO1997030997A1 (en) 1996-02-22 1997-02-21 Tropane-derivatives, their preparation and use

Publications (1)

Publication Number Publication Date
HK1018957A1 true HK1018957A1 (en) 2000-01-14

Family

ID=8090830

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99104015A HK1018957A1 (en) 1996-02-22 1999-09-17 Tropane-derivatives, their preparation and use

Country Status (32)

Country Link
US (3) US6288079B1 (xx)
EP (2) EP1130020A1 (xx)
JP (1) JP3238414B2 (xx)
KR (1) KR100446571B1 (xx)
CN (1) CN1077574C (xx)
AT (1) ATE203023T1 (xx)
AU (1) AU720358B2 (xx)
BG (1) BG63945B1 (xx)
BR (1) BR9707636A (xx)
CA (1) CA2244773C (xx)
CZ (1) CZ287007B6 (xx)
DE (1) DE69705608T2 (xx)
DK (1) DK0885220T3 (xx)
EE (1) EE04751B1 (xx)
ES (1) ES2159839T3 (xx)
GR (1) GR3036829T3 (xx)
HK (1) HK1018957A1 (xx)
HU (1) HU228356B1 (xx)
IL (1) IL125146A (xx)
IS (1) IS1824B (xx)
NO (1) NO318731B1 (xx)
NZ (1) NZ330886A (xx)
PL (1) PL185132B1 (xx)
PT (1) PT885220E (xx)
RU (1) RU2167876C2 (xx)
SG (1) SG99853A1 (xx)
SI (1) SI0885220T1 (xx)
SK (1) SK281813B6 (xx)
TR (1) TR199801641T2 (xx)
UA (1) UA49872C2 (xx)
WO (1) WO1997030997A1 (xx)
ZA (1) ZA971525B (xx)

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Also Published As

Publication number Publication date
EE9800254A (et) 1999-02-15
BR9707636A (pt) 1999-07-27
SI0885220T1 (en) 2001-12-31
ZA971525B (en) 1997-10-21
EP1130020A1 (en) 2001-09-05
US20010018444A1 (en) 2001-08-30
NZ330886A (en) 1999-02-25
IL125146A0 (en) 1999-01-26
NO983877L (no) 1998-08-21
SG99853A1 (en) 2003-11-27
TR199801641T2 (xx) 1998-11-23
HUP9901199A2 (hu) 1999-08-30
IL125146A (en) 2002-03-10
EP0885220A1 (en) 1998-12-23
DK0885220T3 (da) 2001-10-15
NO318731B1 (no) 2005-05-02
PL185132B1 (pl) 2003-02-28
KR19990087127A (ko) 1999-12-15
AU720358B2 (en) 2000-06-01
NO983877D0 (no) 1998-08-21
UA49872C2 (uk) 2002-10-15
IS1824B (is) 2002-10-01
ATE203023T1 (de) 2001-07-15
DE69705608D1 (de) 2001-08-16
SK92998A3 (en) 1998-11-04
JP3238414B2 (ja) 2001-12-17
KR100446571B1 (ko) 2004-11-03
BG102637A (en) 1999-06-30
SK281813B6 (sk) 2001-08-06
US6288079B1 (en) 2001-09-11
US20020128284A1 (en) 2002-09-12
CZ252098A3 (cs) 1998-11-11
EP0885220B1 (en) 2001-07-11
AU1794097A (en) 1997-09-10
IS4825A (is) 1998-08-17
HUP9901199A3 (en) 2001-02-28
CA2244773A1 (en) 1997-08-28
PT885220E (pt) 2001-11-30
CZ287007B6 (en) 2000-08-16
CN1077574C (zh) 2002-01-09
EE04751B1 (et) 2006-12-15
JP2000504739A (ja) 2000-04-18
WO1997030997A1 (en) 1997-08-28
BG63945B1 (bg) 2003-07-31
US6395748B2 (en) 2002-05-28
ES2159839T3 (es) 2001-10-16
DE69705608T2 (de) 2002-05-16
CN1211982A (zh) 1999-03-24
GR3036829T3 (en) 2002-01-31
PL328503A1 (en) 1999-02-01
CA2244773C (en) 2006-01-03
RU2167876C2 (ru) 2001-05-27
HU228356B1 (en) 2013-03-28

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