ZA934971B - Novel phospholipid derivatives - Google Patents

Novel phospholipid derivatives

Info

Publication number
ZA934971B
ZA934971B ZA934971A ZA934971A ZA934971B ZA 934971 B ZA934971 B ZA 934971B ZA 934971 A ZA934971 A ZA 934971A ZA 934971 A ZA934971 A ZA 934971A ZA 934971 B ZA934971 B ZA 934971B
Authority
ZA
South Africa
Prior art keywords
phospholipid derivatives
novel phospholipid
novel
derivatives
medicaments
Prior art date
Application number
ZA934971A
Other languages
English (en)
Inventor
Gerhard Noessner
Juergen Engel
Jurij Stekar
Bernhard Kutscher
Wolfgang Schumacher
Peter Hilgard
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of ZA934971B publication Critical patent/ZA934971B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/5532—Seven-(or more) membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576—Six-membered rings
    • C07F9/59—Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA934971A 1992-07-11 1993-07-09 Novel phospholipid derivatives ZA934971B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4222910A DE4222910A1 (de) 1992-07-11 1992-07-11 Neue Phospholipidderivate

Publications (1)

Publication Number Publication Date
ZA934971B true ZA934971B (en) 1994-02-01

Family

ID=6463031

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA934971A ZA934971B (en) 1992-07-11 1993-07-09 Novel phospholipid derivatives

Country Status (31)

Country Link
EP (1) EP0579939B1 (cs)
JP (1) JP3311431B2 (cs)
KR (1) KR100297180B1 (cs)
CN (1) CN1039012C (cs)
AT (1) ATE176477T1 (cs)
AU (1) AU664101B2 (cs)
BR (1) BR9302809A (cs)
CA (2) CA2100228C (cs)
CZ (1) CZ290863B6 (cs)
DE (2) DE4222910A1 (cs)
DK (1) DK0579939T3 (cs)
EE (1) EE03140B1 (cs)
ES (1) ES2129053T3 (cs)
FI (1) FI111262B (cs)
GR (1) GR3029602T3 (cs)
HR (1) HRP931046B1 (cs)
HU (1) HU218783B (cs)
IL (1) IL106289A (cs)
LT (1) LT3113B (cs)
LV (1) LV10870B (cs)
MX (1) MX9304133A (cs)
NO (1) NO306468B1 (cs)
PL (3) PL177811B1 (cs)
RU (1) RU2108336C1 (cs)
SG (1) SG46249A1 (cs)
SI (1) SI9300365B (cs)
SK (1) SK283827B6 (cs)
TW (1) TW304956B (cs)
UA (1) UA40567C2 (cs)
YU (1) YU49079B (cs)
ZA (1) ZA934971B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101146532B (zh) 2005-01-21 2012-05-09 阿斯泰克斯治疗有限公司 药物化合物
EP1800684A1 (en) * 2005-12-20 2007-06-27 Zentaris GmbH Novel alkyl phospholipid derivatives and uses thereof
AU2006328479B2 (en) * 2005-12-19 2012-03-08 Aeterna Zentaris Gmbh Alkyl phospholipid derivatives with reduced cytotoxicity and uses thereof
EP1869981A1 (de) * 2006-06-21 2007-12-26 Staatliches Weinbauinstitut Freiburg Alkylphospholipide und Lyso-Phospholipide zur Bekämpfung von Pflanzenpathogenen
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8883790B2 (en) 2006-10-12 2014-11-11 Astex Therapeutics Limited Pharmaceutical combinations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4444766A (en) * 1980-10-21 1984-04-24 Boehringer Mannheim Gmbh Sulfur-containing phospholipid compounds and therapeutic compositions
JPS5984824A (ja) * 1982-11-08 1984-05-16 Takeda Chem Ind Ltd 抗腫瘍剤
DE3530767A1 (de) * 1985-08-28 1987-03-12 Max Planck Gesellschaft Mittel gegen multiple sklerose
CA1338627C (en) * 1985-12-04 1996-10-01 Hansjorg Eibl Pharmaceuticals based on phosphoric acid esters for use in tumor therapy, and process for their preparation
JP2512311B2 (ja) * 1986-07-14 1996-07-03 日本ケミファ株式会社 新規なグリセリン誘導体及び血圧降下剤
CN1017435B (zh) * 1987-03-24 1992-07-15 日本化学医药株式会社 新的甘油衍生物的制备方法
DE3906952A1 (de) * 1989-03-04 1990-09-06 Boehringer Mannheim Gmbh (3-(c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)6(pfeil abwaerts)-c(pfeil abwaerts)1(pfeil abwaerts)(pfeil abwaerts)8(pfeil abwaerts))alkansulfinyl- und sulfonyl-2-methoxymethyl-propyl)-(2-trimethylammonio-ethyl) phosphate, verfahren zu deren herstellung diese verbindungen enthaltende arzneimittel
DE3942933A1 (de) * 1989-12-23 1991-06-27 Boehringer Mannheim Gmbh Verwendung von alkylphospholipiden als antivirale arzneimittel und neue phospholipid-derivate
DE4114586A1 (de) * 1991-05-04 1992-11-05 Boehringer Mannheim Gmbh Arzneimittel enthaltend azacyclodiphosphonsaeurederivate, neue azacyclodiphosphonsaeurederivate sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
LT3113B (en) 1994-12-27
AU4186493A (en) 1994-01-13
CZ290863B6 (cs) 2002-11-13
SI9300365A (en) 1994-03-31
AU664101B2 (en) 1995-11-02
PL175607B1 (pl) 1999-01-29
IL106289A (en) 2000-06-01
HUT64548A (en) 1994-01-28
GR3029602T3 (en) 1999-06-30
UA40567C2 (uk) 2001-08-15
SK283827B6 (sk) 2004-02-03
HU218783B (hu) 2000-12-28
LV10870A (lv) 1995-10-20
CN1084175A (zh) 1994-03-23
CZ124993A3 (en) 1995-03-15
KR100297180B1 (ko) 2001-11-30
DE4222910A1 (de) 1994-01-13
NO306468B1 (no) 1999-11-08
RU2108336C1 (ru) 1998-04-10
YU49079B (sh) 2003-08-29
ATE176477T1 (de) 1999-02-15
TW304956B (cs) 1997-05-11
BR9302809A (pt) 1994-03-15
FI111262B (fi) 2003-06-30
PL177811B1 (pl) 2000-01-31
CA2511753C (en) 2007-09-25
NO932502L (no) 1994-01-12
YU47393A (sh) 1997-08-22
FI933165A7 (fi) 1994-01-12
SK67093A3 (en) 1995-03-08
HRP931046B1 (en) 2000-06-30
CA2100228A1 (en) 1994-01-12
CA2100228C (en) 2006-01-24
KR940002265A (ko) 1994-02-17
JPH0733791A (ja) 1995-02-03
FI933165A0 (fi) 1993-07-09
DK0579939T3 (da) 1999-09-20
JP3311431B2 (ja) 2002-08-05
DE59309355D1 (de) 1999-03-18
LV10870B (en) 1996-06-20
ES2129053T3 (es) 1999-06-01
EP0579939A1 (de) 1994-01-26
PL299624A1 (en) 1994-02-21
MX9304133A (es) 1994-04-29
NO932502D0 (no) 1993-07-08
EP0579939B1 (de) 1999-02-03
HRP931046A2 (en) 1997-04-30
PL173388B1 (pl) 1998-02-27
LTIP620A (en) 1994-07-15
CN1039012C (zh) 1998-07-08
CA2511753A1 (en) 1994-01-12
IL106289A0 (en) 1994-04-12
SI9300365B (sl) 2002-02-28
SG46249A1 (en) 1998-02-20
HU9301992D0 (en) 1993-09-28
EE03140B1 (et) 1998-12-15

Similar Documents

Publication Publication Date Title
EP0595133A3 (de) Prodrugs, ihre Herstellung und Verwendung als Arzneimittel
AU8065587A (en) 3,4-dihydro-3-phenyl-2H-1-benzopyran derivatives
AU7368187A (en) 1,2,3,6-tetrahydro-5-nitro-pyrimidine derivatives
GR3024859T3 (en) 4,13-dioxabicyclo[8.2.1]tridecenon-derivatives, method and intermediates for their preparation, and medicaments containing the same
MY128260A (en) Cyclopentane-and-pentene-b-amino acids
AU570328B2 (en) Solid medicament formulations containing dihydropyridines
GB2173195B (en) N,n'-diaminocarbonylmethyl-n,n'-dicarboxymethyl-1,2-diaminoethane derivatives
ZA934971B (en) Novel phospholipid derivatives
AU1630188A (en) Substituted compounds, processes for their preparation and their use as medicaments
AU1174588A (en) Anticonvulsant agents
EP0401262A4 (en) 24r-scymnol, and preparation and use thereof
AU7519987A (en) 1,1,2-triaryl-1-alkene derivatives
YU12189A (en) Derivatives tetrahydropyridin
AU2823089A (en) 2,4- diaminoquinazoline derivatives
AU637400B2 (en) Substituted vinylcephalosporins, processes for their preparation and their use as medicaments
IL100940A0 (en) 17-beta-oestradiol derivatives,processes for their preparation and medicaments containing them
AU7010687A (en) 1,3-dithiol-2-ylidene-sulfonylacetate derivatives