ZA201506918B - Cytotoxic and anti-mitotic compounds, and methods of using the same - Google Patents

Cytotoxic and anti-mitotic compounds, and methods of using the same

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Publication number
ZA201506918B
ZA201506918B ZA2015/06918A ZA201506918A ZA201506918B ZA 201506918 B ZA201506918 B ZA 201506918B ZA 2015/06918 A ZA2015/06918 A ZA 2015/06918A ZA 201506918 A ZA201506918 A ZA 201506918A ZA 201506918 B ZA201506918 B ZA 201506918B
Authority
ZA
South Africa
Prior art keywords
cytotoxic
methods
same
mitotic compounds
mitotic
Prior art date
Application number
ZA2015/06918A
Other languages
English (en)
Inventor
Babcook John
Marie Josée Bourque Elyse
Han Hsiao Hsieh Tom
John Hedberg Bradley
R Rich James
Laurence Mandel Alexander
C Winters Geoffrey
Original Assignee
The Centre For Drug Res And Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Centre For Drug Res And Development filed Critical The Centre For Drug Res And Development
Publication of ZA201506918B publication Critical patent/ZA201506918B/en

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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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