ZA200510421B - Nicotinamide derivatives useful as pde4 inhibitors - Google Patents

Nicotinamide derivatives useful as pde4 inhibitors Download PDF

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Publication number
ZA200510421B
ZA200510421B ZA200510421A ZA200510421A ZA200510421B ZA 200510421 B ZA200510421 B ZA 200510421B ZA 200510421 A ZA200510421 A ZA 200510421A ZA 200510421 A ZA200510421 A ZA 200510421A ZA 200510421 B ZA200510421 B ZA 200510421B
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South Africa
Prior art keywords
asthma
compound
disease
preparation
formula
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ZA200510421A
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English (en)
Inventor
Barber Christopher Gordon
Bunnage Mark Edward
Harvey John Wilson
Mathias John Paul
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Pfizer
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Publication of ZA200510421B publication Critical patent/ZA200510421B/en

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ZA200510421A 2003-07-25 2005-12-22 Nicotinamide derivatives useful as pde4 inhibitors ZA200510421B (en)

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AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
CA2594785A1 (en) * 2005-01-21 2006-07-27 Pfizer Limited Crystalline forms cis-5-fluoro-n-[4-(2-hydroxy-4-methylbenzamido) cyclohexyl]-2-(tetrahydrothiopyran-a-yloxy) nicotinamide
EP1683795A1 (en) * 2005-01-21 2006-07-26 Pfizer Limited Crystalline forms of cis-5-fluoro-N-¬4-(2-hydroxy-4-methylbenzamido)cyclohexyl|-2-(tetrahydrothiopyran-4-yloxy)nicotinamide
JP2008536888A (ja) * 2005-04-19 2008-09-11 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺高血圧症の治療のためのロフルミラスト
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
US7926591B2 (en) * 2006-02-10 2011-04-19 Halliburton Energy Services, Inc. Aqueous-based emulsified consolidating agents suitable for use in drill-in applications
WO2007101161A2 (en) * 2006-02-24 2007-09-07 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
PL2280696T3 (pl) * 2008-03-18 2015-03-31 Arena Pharm Inc Modulatory receptora prostacykliny (PGI2) użyteczne do leczenia zaburzeń z nim związanych
CN103880757B (zh) * 2014-04-15 2016-02-24 上海毕得医药科技有限公司 一种5-羟基嘧啶-2-羧酸的合成方法
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JP2023508978A (ja) * 2019-12-23 2023-03-06 サンフォード バーナム プレビス メディカル ディスカバリー インスティテュート エクトヌクレオチドピロホスファターゼ／ホスホジエステラーゼ１（ｅｎｐｐ１）モジュレーター及びその使用
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ID22781A (id) * 1997-04-04 1999-12-09 Pfizer Prod Inc Turunan-turunan nikotinamida
US20020111495A1 (en) * 1997-04-04 2002-08-15 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
US6740655B2 (en) * 2000-01-31 2004-05-25 Pfizer Inc Pyrimidine carboxamides useful as inhibitors of PDE4 isozymes
MXPA02007419A (es) * 2000-01-31 2002-12-09 Pfizer Prod Inc Derivados de nicotinamida benzocondensada-heterociclilo utiles como inhibidores selectivos de las isozimas pde4.
EP1355884A1 (en) * 2001-01-31 2003-10-29 Pfizer Products Inc. Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes
EE200300362A (et) * 2001-01-31 2003-12-15 Pfizer Products Inc. PDE4 isosüümide inhibiitoritena kasutatavad tiasolüül-, oksasolüül-, pürrolüül- ja imidasolüülhappeamiidi derivaadid

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ATE362930T1 (de) 2007-06-15
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