ZA200504996B - Recombinant VHH single domain antibody from camelldao against von Willebrand Factor (vWF) or against collagen - Google Patents

Recombinant VHH single domain antibody from camelldao against von Willebrand Factor (vWF) or against collagen Download PDF

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Publication number
ZA200504996B
ZA200504996B ZA200504996A ZA200504996A ZA200504996B ZA 200504996 B ZA200504996 B ZA 200504996B ZA 200504996 A ZA200504996 A ZA 200504996A ZA 200504996 A ZA200504996 A ZA 200504996A ZA 200504996 B ZA200504996 B ZA 200504996B
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South Africa
Prior art keywords
polypeptide
vwf
polypeptide construct
construct according
single domain
Prior art date
Application number
ZA200504996A
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English (en)
Inventor
Silence Karen
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Ablynx Nv
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Publication of ZA200504996B publication Critical patent/ZA200504996B/en

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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ZA200504996A 2003-01-10 2005-06-20 Recombinant VHH single domain antibody from camelldao against von Willebrand Factor (vWF) or against collagen ZA200504996B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03447005 2003-01-10

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ZA200504996B true ZA200504996B (en) 2008-02-27

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US (3) US9028816B2 (es)
EP (2) EP2390270A1 (es)
JP (1) JP2006517789A (es)
KR (2) KR20080113286A (es)
CN (2) CN101412759A (es)
AU (1) AU2004204262B2 (es)
BR (1) BRPI0406694B8 (es)
CA (1) CA2512545C (es)
ES (1) ES2542330T3 (es)
MX (1) MXPA05006043A (es)
NO (1) NO337265B1 (es)
NZ (1) NZ540771A (es)
RU (1) RU2357974C2 (es)
WO (1) WO2004062551A2 (es)
ZA (1) ZA200504996B (es)

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EP1527346B1 (en) 2002-08-07 2011-06-08 Ablynx N.V. Modulation of platelet adhesion based on the surface exposed beta-switch loop of platelet glycoprotein ib-alpha
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
US9320792B2 (en) * 2002-11-08 2016-04-26 Ablynx N.V. Pulmonary administration of immunoglobulin single variable domains and constructs thereof
EP2390270A1 (en) 2003-01-10 2011-11-30 Ablynx N.V. Therapeutic polypeptides, homologues thereof, fragments thereof and for use in modulating platelet-mediated aggregation
WO2005077980A2 (en) * 2004-02-13 2005-08-25 Bioceros Bv Soluble tcr-like molecules and their uses
AU2005269527B2 (en) 2004-07-26 2011-12-01 Pfenex Inc. Process for improved protein expression by strain engineering
KR20070084069A (ko) 2004-10-08 2007-08-24 도만티스 리미티드 Ｔｎｆｒ1에 대한 단일 도메인 항체 및 이의 사용 방법
CA2593328C (en) * 2005-01-14 2018-02-06 Ablynx N.V. Methods and assays for distinguishing between different forms of diseases and disorders characterized by thrombocytopenia and/or by spontaneous interaction between von willebrand factor (vwf) and platelets
AU2006213411B2 (en) * 2005-02-14 2010-09-23 Alfresa Pharma Corporation Antibody for assay of ADAMTS13 activity and method of activity assay
AU2006224438A1 (en) * 2005-03-18 2006-09-21 Antonio Cassone Antibodies against Candida antigens
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