ZA200308172B - Use of IL-18 inhibitors for treating or preventing CNS injuries. - Google Patents
Use of IL-18 inhibitors for treating or preventing CNS injuries.Info
- Publication number
- ZA200308172B ZA200308172B ZA200308172A ZA200308172A ZA200308172B ZA 200308172 B ZA200308172 B ZA 200308172B ZA 200308172 A ZA200308172 A ZA 200308172A ZA 200308172 A ZA200308172 A ZA 200308172A ZA 200308172 B ZA200308172 B ZA 200308172B
- Authority
- ZA
- South Africa
- Prior art keywords
- inhibitors
- treating
- cns injuries
- preventing cns
- preventing
- Prior art date
Links
- 230000006378 damage Effects 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01112067 | 2001-05-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200308172B true ZA200308172B (en) | 2004-10-21 |
Family
ID=8177454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200308172A ZA200308172B (en) | 2001-05-25 | 2003-10-21 | Use of IL-18 inhibitors for treating or preventing CNS injuries. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US7655616B2 (cs) |
| EP (1) | EP1390070B1 (cs) |
| JP (1) | JP4344142B2 (cs) |
| KR (1) | KR20040030625A (cs) |
| CN (1) | CN1305529C (cs) |
| AU (1) | AU2002314103B2 (cs) |
| BG (1) | BG66395B1 (cs) |
| BR (1) | BR0210007A (cs) |
| CA (1) | CA2445664C (cs) |
| CY (1) | CY1119190T1 (cs) |
| CZ (1) | CZ307321B6 (cs) |
| DK (1) | DK1390070T3 (cs) |
| EA (1) | EA006744B1 (cs) |
| EE (1) | EE05263B1 (cs) |
| ES (1) | ES2617084T3 (cs) |
| HR (1) | HRP20030842B1 (cs) |
| HU (1) | HU230294B1 (cs) |
| IL (2) | IL159014A0 (cs) |
| LT (1) | LT1390070T (cs) |
| ME (1) | ME00550B (cs) |
| MX (1) | MXPA03010743A (cs) |
| NO (1) | NO331882B1 (cs) |
| PL (1) | PL216228B1 (cs) |
| PT (1) | PT1390070T (cs) |
| RS (1) | RS56006B1 (cs) |
| SK (1) | SK288413B6 (cs) |
| UA (1) | UA80396C2 (cs) |
| WO (1) | WO2002096456A1 (cs) |
| ZA (1) | ZA200308172B (cs) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1622939B1 (en) | 2003-05-13 | 2012-03-14 | Merck Serono SA | Active variants of the il-18 binding protein and medical uses thereof |
| DK2177907T3 (da) * | 2004-06-30 | 2014-03-24 | Atsuo Sekiyama | Indikatormiddel til ikke-inflammatorisk stressreaktion og anvendelse dertil |
| PT1885753E (pt) | 2005-06-03 | 2011-10-06 | Ares Trading Sa | Produção de proteína recombinante de ligação a il-18 |
| DK1888100T3 (da) * | 2005-06-03 | 2012-01-23 | Merck Serono Sa | Anvendelse af IL-18BP-isoformer til behandling og/eller forebyggelse af neurologiske inflammatoriske sygdomme |
| EP1891088B1 (en) | 2005-06-10 | 2011-10-19 | Ares Trading S.A. | Process for the purification of il-18 binding protein |
| US8685400B2 (en) | 2007-07-30 | 2014-04-01 | University Of Miami | Modulating inflammasome activity and inflammation in the central nervous system |
| UA125204C2 (uk) * | 2013-09-05 | 2022-02-02 | Аб2 Біо Са | Застосування il-18-зв'язувального білка (il-18bp) при запальних захворюваннях |
| UA128752C2 (uk) * | 2015-03-05 | 2024-10-16 | Аб2 Біо Са | Фармацевтична композиція для лікування асоційованого з il-18 захворювання або порушення |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0873453A (ja) * | 1994-09-02 | 1996-03-19 | Otsuka Pharmaceut Co Ltd | サイトカイン阻害剤 |
| IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
| JP4499917B2 (ja) * | 1998-03-09 | 2010-07-14 | バーテックス ファーマシューティカルズ インコーポレイテッド | インターロイキン−１β変換酵素のインヒビターとしての１，２−ジアゼパン誘導体 |
| CA2276216A1 (en) * | 1998-06-24 | 1999-12-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | An artificial peptide capable of neutralizing the biological activity of interleukin-18 |
| ES2305082T3 (es) * | 2000-05-05 | 2008-11-01 | Laboratoires Serono Sa | Uso de inhibidores de il-18 para el tratamiento y/o la prevencion de la aterosclerosis. |
| EP1292288B1 (en) * | 2000-06-23 | 2004-09-29 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | 2-arachidonylglycerol (2-ag) - an inhibitor of tumor necrosis factor -alfa and neuroprotector of brain in closed head injury |
| AU2002224417A1 (en) * | 2000-10-18 | 2002-04-29 | Immunex Corporation | Methods for treating il-18 mediated disorders |
| US6671553B1 (en) * | 2001-05-23 | 2003-12-30 | Pacesetter, Inc. | Implantable cardiac lead having terminating connector strain relief and method of manufacture |
-
2002
- 2002-05-23 EP EP02740641.2A patent/EP1390070B1/en not_active Expired - Lifetime
- 2002-05-23 BR BR0210007-0A patent/BR0210007A/pt not_active Application Discontinuation
- 2002-05-23 MX MXPA03010743A patent/MXPA03010743A/es active IP Right Grant
- 2002-05-23 WO PCT/EP2002/005666 patent/WO2002096456A1/en not_active Ceased
- 2002-05-23 ME MEP-2008-618A patent/ME00550B/me unknown
- 2002-05-23 EA EA200301299A patent/EA006744B1/ru not_active IP Right Cessation
- 2002-05-23 KR KR10-2003-7015310A patent/KR20040030625A/ko not_active Ceased
- 2002-05-23 PT PT2740641T patent/PT1390070T/pt unknown
- 2002-05-23 IL IL15901402A patent/IL159014A0/xx unknown
- 2002-05-23 EE EEP200300582A patent/EE05263B1/xx unknown
- 2002-05-23 SK SK1603-2003A patent/SK288413B6/sk not_active IP Right Cessation
- 2002-05-23 HR HRP20030842AA patent/HRP20030842B1/hr not_active IP Right Cessation
- 2002-05-23 HU HU0304067A patent/HU230294B1/hu unknown
- 2002-05-23 JP JP2002592965A patent/JP4344142B2/ja not_active Expired - Lifetime
- 2002-05-23 UA UA20031212328A patent/UA80396C2/uk unknown
- 2002-05-23 ES ES02740641.2T patent/ES2617084T3/es not_active Expired - Lifetime
- 2002-05-23 DK DK02740641.2T patent/DK1390070T3/en active
- 2002-05-23 RS YU89403A patent/RS56006B1/sr unknown
- 2002-05-23 LT LTEP02740641.2T patent/LT1390070T/lt unknown
- 2002-05-23 CN CNB028147510A patent/CN1305529C/zh not_active Expired - Lifetime
- 2002-05-23 CZ CZ2003-3268A patent/CZ307321B6/cs not_active IP Right Cessation
- 2002-05-23 AU AU2002314103A patent/AU2002314103B2/en not_active Expired
- 2002-05-23 CA CA2445664A patent/CA2445664C/en not_active Expired - Lifetime
- 2002-05-23 PL PL367545A patent/PL216228B1/pl unknown
- 2002-05-23 US US10/478,614 patent/US7655616B2/en not_active Expired - Lifetime
-
2003
- 2003-10-21 ZA ZA200308172A patent/ZA200308172B/xx unknown
- 2003-11-20 NO NO20035160A patent/NO331882B1/no not_active IP Right Cessation
- 2003-11-23 IL IL159014A patent/IL159014A/en active IP Right Grant
- 2003-12-15 BG BG108451A patent/BG66395B1/bg unknown
-
2017
- 2017-05-08 CY CY20171100494T patent/CY1119190T1/el unknown
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