DK2177907T3 - Indikatormiddel til ikke-inflammatorisk stressreaktion og anvendelse dertil - Google Patents

Indikatormiddel til ikke-inflammatorisk stressreaktion og anvendelse dertil

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Publication number
DK2177907T3
DK2177907T3 DK10000021.5T DK10000021T DK2177907T3 DK 2177907 T3 DK2177907 T3 DK 2177907T3 DK 10000021 T DK10000021 T DK 10000021T DK 2177907 T3 DK2177907 T3 DK 2177907T3
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DK
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Prior art keywords
indicator
stress response
inflammatory stress
inflammatory
response
Prior art date
Application number
DK10000021.5T
Other languages
English (en)
Inventor
Atsuo Sekiyama
Original Assignee
Atsuo Sekiyama
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Publication of DK2177907T3 publication Critical patent/DK2177907T3/da

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    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5412—IL-6
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90283—Oxidoreductases (1.) acting on superoxide radicals as acceptor (1.15)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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DK10000021.5T 2004-06-30 2005-06-29 Indikatormiddel til ikke-inflammatorisk stressreaktion og anvendelse dertil DK2177907T3 (da)

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WO2007094472A1 (ja) 2006-02-17 2007-08-23 Atsuo Sekiyama 生体負荷の指標剤および生体負荷の測定方法
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JP5669349B2 (ja) * 2008-08-26 2015-02-12 株式会社バイオマーカーサイエンス 生体内緊張状態の緩和・誘導抑制効果の評価方法、並びに、物質のスクリーニング方法
JP5219048B2 (ja) * 2008-09-17 2013-06-26 独立行政法人農業・食品産業技術総合研究機構 抗豚インターロイキン−１８抗体を用いた動物のストレス評価方法
WO2010086972A1 (ja) * 2009-01-28 2010-08-05 Sekiyama Atsuo 抗ストレス剤
JP5846604B2 (ja) * 2012-03-23 2016-01-20 国立研究開発法人産業技術総合研究所 行動リズムモニタリング用バイオマーカー
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AU4260497A (en) * 1996-09-09 1998-03-26 Cornell Research Foundation Inc. Interferon-gamma inducing factor in neuroendocrine cells
US6221856B1 (en) * 1999-02-03 2001-04-24 Inologic, Inc. Inositol derivatives for inhibiting superoxide anion production
ATE349526T1 (de) * 1999-05-25 2007-01-15 Immunex Corp Il-1 eta dna und polypeptide
EP1257585A2 (en) * 2000-02-10 2002-11-20 Basf Aktiengesellschaft Antibodies that bind human interleukin-18 and methods of making and using
SK288032B6 (sk) * 2000-02-21 2012-12-03 Merck Serono Sa Use of IL-18 inhibitors for manufacture of medicament for treatment and/or prevention of alcoholic hepatitis
JP3538616B2 (ja) * 2000-04-25 2004-06-14 友昭 星野 間質性肺炎治療薬および当該疾病の動物モデルの作成方法並びにそれを用いるスクリーニング方法
BR0210007A (pt) * 2001-05-25 2004-08-10 Ares Trading Sa Uso de inibidores de il-18 para tratamento ou prevenção de lesões do sistema nervoso central
UA78516C2 (en) * 2001-08-10 2007-04-10 Applied Research Systems Use of inhibitors of il-18 for treatment and/or prevention of hypersensitivity disorders, and in particular of delayed-type hypersensitivity
US6503506B1 (en) * 2001-08-10 2003-01-07 Millenium Biotechnologies, Inc. Nutrient therapy for immuno-compromised patients
WO2004020552A1 (ja) * 2002-08-30 2004-03-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo ラジカル反応抑制剤及びラジカル反応抑制方法並びにその用途

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EP1780542A1 (en) 2007-05-02
JPWO2006003927A1 (ja) 2008-07-31
AU2005258569A1 (en) 2006-01-12
EP2177907B1 (en) 2014-01-01
US20140065641A1 (en) 2014-03-06
EP2177907A3 (en) 2010-07-28
AU2005258569B2 (en) 2012-05-03
EP1780542A4 (en) 2008-05-14
WO2006003927A1 (ja) 2006-01-12
US20120258468A1 (en) 2012-10-11
NZ552908A (en) 2009-11-27
EP2177907A2 (en) 2010-04-21
JP5069000B2 (ja) 2012-11-07
US20090004683A1 (en) 2009-01-01
HK1143416A1 (en) 2010-12-31

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