LT1390070T - Il-18 inhibitoriaus panaudojimas cns pažeidimų gydymui arba prevencijai - Google Patents

Il-18 inhibitoriaus panaudojimas cns pažeidimų gydymui arba prevencijai

Info

Publication number
LT1390070T
LT1390070T LTEP02740641.2T LT02740641T LT1390070T LT 1390070 T LT1390070 T LT 1390070T LT 02740641 T LT02740641 T LT 02740641T LT 1390070 T LT1390070 T LT 1390070T
Authority
LT
Lithuania
Prior art keywords
inhibitors
treating
cns injuries
preventing cns
preventing
Prior art date
Application number
LTEP02740641.2T
Other languages
English (en)
Inventor
Esther Shohami
Original Assignee
Ares Trading S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading S.A. filed Critical Ares Trading S.A.
Publication of LT1390070T publication Critical patent/LT1390070T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
LTEP02740641.2T 2001-05-25 2002-05-23 Il-18 inhibitoriaus panaudojimas cns pažeidimų gydymui arba prevencijai LT1390070T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01112067 2001-05-25
PCT/EP2002/005666 WO2002096456A1 (en) 2001-05-25 2002-05-23 Use of il-18 inhibitors for treating or preventing cns injuries

Publications (1)

Publication Number Publication Date
LT1390070T true LT1390070T (lt) 2017-03-10

Family

ID=8177454

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP02740641.2T LT1390070T (lt) 2001-05-25 2002-05-23 Il-18 inhibitoriaus panaudojimas cns pažeidimų gydymui arba prevencijai

Country Status (30)

Country Link
US (1) US7655616B2 (lt)
EP (1) EP1390070B1 (lt)
JP (1) JP4344142B2 (lt)
KR (1) KR20040030625A (lt)
CN (1) CN1305529C (lt)
AU (1) AU2002314103B2 (lt)
BG (1) BG66395B1 (lt)
BR (1) BR0210007A (lt)
CA (1) CA2445664C (lt)
CY (1) CY1119190T1 (lt)
CZ (1) CZ307321B6 (lt)
DK (1) DK1390070T3 (lt)
EA (1) EA006744B1 (lt)
EE (1) EE05263B1 (lt)
ES (1) ES2617084T3 (lt)
HK (1) HK1069762A1 (lt)
HR (1) HRP20030842B1 (lt)
HU (1) HU230294B1 (lt)
IL (2) IL159014A0 (lt)
LT (1) LT1390070T (lt)
ME (1) ME00550B (lt)
MX (1) MXPA03010743A (lt)
NO (1) NO331882B1 (lt)
PL (1) PL216228B1 (lt)
PT (1) PT1390070T (lt)
RS (1) RS56006B1 (lt)
SK (1) SK288413B6 (lt)
UA (1) UA80396C2 (lt)
WO (1) WO2002096456A1 (lt)
ZA (1) ZA200308172B (lt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1622939B1 (en) 2003-05-13 2012-03-14 Merck Serono SA Active variants of the il-18 binding protein and medical uses thereof
AU2005258569B2 (en) * 2004-06-30 2012-05-03 Atsuo Sekiyama Indicator agent for noninflammatory stress response and use thereof
EP1885753B1 (en) 2005-06-03 2011-07-27 Ares Trading S.A. Production of recombinant Il-18 binding protein
CA2610691C (en) * 2005-06-03 2015-12-01 Laboratoires Serono S.A. Use of il-18bp isoforms for the treatment and/or prevention of neurological inflammatory diseases
PT1891088E (pt) 2005-06-10 2011-12-19 Ares Trading Sa Processo para a purificação da proteína de ligação il-18
US8685400B2 (en) 2007-07-30 2014-04-01 University Of Miami Modulating inflammasome activity and inflammation in the central nervous system
PL3041864T3 (pl) * 2013-09-05 2021-12-20 Ab2 Bio Sa Białko wiążące il-18 (il-18bp) w chorobach zapalnych
MY194040A (en) * 2015-03-05 2022-11-09 Ab2 Bio Sa Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0873453A (ja) * 1994-09-02 1996-03-19 Otsuka Pharmaceut Co Ltd サイトカイン阻害剤
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
JP4499917B2 (ja) * 1998-03-09 2010-07-14 バーテックス ファーマシューティカルズ インコーポレイテッド インターロイキン−1β変換酵素のインヒビターとしての1,2−ジアゼパン誘導体
CA2276216A1 (en) * 1998-06-24 1999-12-24 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo An artificial peptide capable of neutralizing the biological activity of interleukin-18
UA87658C2 (uk) * 2000-05-05 2009-08-10 Апплайд Резеч Системз Арс Холдинг Н.В. Застосування il-18 як діагностичного маркера серцевої недостатності
DE60106026T2 (de) * 2000-06-23 2006-02-23 Yissum Research Development Company Of The Hebrew University Of Jerusalem 2-arachidonylglycerol (2-ag)-ein hemmer des tumor nekrose faktors-alfa und neuroprotektor des gehirns bei geschlossenen kopfverletzungen
AU2002224417A1 (en) * 2000-10-18 2002-04-29 Immunex Corporation Methods for treating il-18 mediated disorders
US6671553B1 (en) * 2001-05-23 2003-12-30 Pacesetter, Inc. Implantable cardiac lead having terminating connector strain relief and method of manufacture

Also Published As

Publication number Publication date
HK1069762A1 (en) 2005-06-03
JP2004534777A (ja) 2004-11-18
CA2445664C (en) 2012-03-06
MXPA03010743A (es) 2004-03-02
CZ20033268A3 (en) 2004-07-14
EA006744B1 (ru) 2006-04-28
CN1305529C (zh) 2007-03-21
KR20040030625A (ko) 2004-04-09
DK1390070T3 (en) 2017-04-24
HU230294B1 (hu) 2015-12-28
SK288413B6 (sk) 2016-10-03
HRP20030842B1 (hr) 2017-06-02
EE05263B1 (et) 2010-02-15
EP1390070A1 (en) 2004-02-25
NO20035160D0 (no) 2003-11-20
UA80396C2 (en) 2007-09-25
AU2002314103B8 (en) 2002-12-09
PT1390070T (pt) 2017-03-01
AU2002314103B2 (en) 2007-07-12
CN1535160A (zh) 2004-10-06
JP4344142B2 (ja) 2009-10-14
NO331882B1 (no) 2012-04-23
US20040191247A1 (en) 2004-09-30
HUP0304067A2 (hu) 2004-03-29
BG108451A (en) 2005-02-28
ES2617084T3 (es) 2017-06-15
NO20035160L (no) 2003-11-20
EA200301299A1 (ru) 2004-04-29
EE200300582A (et) 2004-02-16
PL216228B1 (pl) 2014-03-31
US7655616B2 (en) 2010-02-02
EP1390070B1 (en) 2017-02-08
IL159014A0 (en) 2004-05-12
BG66395B1 (bg) 2013-12-31
HUP0304067A3 (en) 2006-01-30
CZ307321B6 (cs) 2018-06-06
RS56006B1 (sr) 2017-09-29
SK16032003A3 (sk) 2004-05-04
YU89403A (sh) 2006-05-25
PL367545A1 (en) 2005-02-21
HRP20030842A2 (en) 2005-08-31
WO2002096456A1 (en) 2002-12-05
CA2445664A1 (en) 2002-12-05
CY1119190T1 (el) 2018-02-14
ME00550B (me) 2011-10-10
ZA200308172B (en) 2004-10-21
BR0210007A (pt) 2004-08-10
IL159014A (en) 2012-05-31

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