ZA200304894B - Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes. - Google Patents

Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes. Download PDF

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Publication number
ZA200304894B
ZA200304894B ZA200304894A ZA200304894A ZA200304894B ZA 200304894 B ZA200304894 B ZA 200304894B ZA 200304894 A ZA200304894 A ZA 200304894A ZA 200304894 A ZA200304894 A ZA 200304894A ZA 200304894 B ZA200304894 B ZA 200304894B
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South Africa
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formula
group
alkyl
fluoro
asthma
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ZA200304894A
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English (en)
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Chambers Robert James
Magee Thomas Victor
Anthony Marfat
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Pfizer Prod Inc
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Publication of ZA200304894B publication Critical patent/ZA200304894B/en

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    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
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    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
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ZA200304894A 2001-01-31 2003-06-24 Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes. ZA200304894B (en)

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US26549201P 2001-01-31 2001-01-31

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ZA200304894A ZA200304894B (en) 2001-01-31 2003-06-24 Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes.

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US (2) US6649633B2 (es)
EP (1) EP1355884A1 (es)
JP (1) JP2004520386A (es)
KR (1) KR20030074761A (es)
CN (1) CN1518542A (es)
BG (1) BG108038A (es)
BR (1) BR0116852A (es)
CA (1) CA2436535A1 (es)
CR (1) CR7025A (es)
CZ (1) CZ20031895A3 (es)
EA (1) EA200300621A1 (es)
EC (2) ECSP034709A (es)
EE (1) EE200300360A (es)
HU (1) HUP0400637A2 (es)
IL (1) IL156413A0 (es)
IS (1) IS6846A (es)
MA (1) MA26983A1 (es)
MX (1) MXPA03006887A (es)
NO (1) NO20033397L (es)
NZ (1) NZ526453A (es)
OA (1) OA12540A (es)
PL (1) PL364135A1 (es)
SK (1) SK8792003A3 (es)
WO (1) WO2002060875A1 (es)
ZA (1) ZA200304894B (es)

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