IS6846A - Nikotínamíð bíarýlafleiður, nytsamlegar sem hindrar PDE4 samsætuensíma - Google Patents

Nikotínamíð bíarýlafleiður, nytsamlegar sem hindrar PDE4 samsætuensíma

Info

Publication number
IS6846A
IS6846A IS6846A IS6846A IS6846A IS 6846 A IS6846 A IS 6846A IS 6846 A IS6846 A IS 6846A IS 6846 A IS6846 A IS 6846A IS 6846 A IS6846 A IS 6846A
Authority
IS
Iceland
Prior art keywords
baryl
isotopic
nicotinamide
enzymes
derivatives useful
Prior art date
Application number
IS6846A
Other languages
English (en)
Inventor
James Chambers Robert
Victor Magee Thomas
Marfat Anthony
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS6846A publication Critical patent/IS6846A/is

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychology (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
IS6846A 2001-01-31 2003-06-16 Nikotínamíð bíarýlafleiður, nytsamlegar sem hindrar PDE4 samsætuensíma IS6846A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26549201P 2001-01-31 2001-01-31
PCT/IB2001/002341 WO2002060875A1 (en) 2001-01-31 2001-12-06 Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes

Publications (1)

Publication Number Publication Date
IS6846A true IS6846A (is) 2003-06-16

Family

ID=23010671

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6846A IS6846A (is) 2001-01-31 2003-06-16 Nikotínamíð bíarýlafleiður, nytsamlegar sem hindrar PDE4 samsætuensíma

Country Status (25)

Country Link
US (2) US6649633B2 (is)
EP (1) EP1355884A1 (is)
JP (1) JP2004520386A (is)
KR (1) KR20030074761A (is)
CN (1) CN1518542A (is)
BG (1) BG108038A (is)
BR (1) BR0116852A (is)
CA (1) CA2436535A1 (is)
CR (1) CR7025A (is)
CZ (1) CZ20031895A3 (is)
EA (1) EA200300621A1 (is)
EC (2) ECSP034710A (is)
EE (1) EE200300360A (is)
HU (1) HUP0400637A2 (is)
IL (1) IL156413A0 (is)
IS (1) IS6846A (is)
MA (1) MA26983A1 (is)
MX (1) MXPA03006887A (is)
NO (1) NO20033397L (is)
NZ (1) NZ526453A (is)
OA (1) OA12540A (is)
PL (1) PL364135A1 (is)
SK (1) SK8792003A3 (is)
WO (1) WO2002060875A1 (is)
ZA (1) ZA200304894B (is)

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EP1424101A3 (en) * 2002-11-29 2004-08-18 NOZAKI, Masako Use of a leukotriene C4 and D4 receptor antagonist for the preparation of a medicament for treating or preventing brain inflammation and sepsis
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GB0317484D0 (en) * 2003-07-25 2003-08-27 Pfizer Ltd Nicotinamide derivatives useful as pde4 inhibitors
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GB0317498D0 (en) * 2003-07-25 2003-08-27 Pfizer Ltd Compounds
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TWI385169B (zh) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
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