IS6421A - Nikótínamíð bensósambræddar-heterósýklýl afleiðurnytsamlegar sem valvísir latar á PDE4 samsætuensím - Google Patents
Nikótínamíð bensósambræddar-heterósýklýl afleiðurnytsamlegar sem valvísir latar á PDE4 samsætuensímInfo
- Publication number
- IS6421A IS6421A IS6421A IS6421A IS6421A IS 6421 A IS6421 A IS 6421A IS 6421 A IS6421 A IS 6421A IS 6421 A IS6421 A IS 6421A IS 6421 A IS6421 A IS 6421A
- Authority
- IS
- Iceland
- Prior art keywords
- benzosubstituted
- pde4
- nicotinamide
- selective inhibitor
- derivative useful
- Prior art date
Links
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 title 2
- 101100296720 Dictyostelium discoideum Pde4 gene Proteins 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 101100082610 Plasmodium falciparum (isolate 3D7) PDEdelta gene Proteins 0.000 title 1
- 229940124639 Selective inhibitor Drugs 0.000 title 1
- 230000000155 isotopic effect Effects 0.000 title 1
- 229960003966 nicotinamide Drugs 0.000 title 1
- 235000005152 nicotinamide Nutrition 0.000 title 1
- 239000011570 nicotinamide Substances 0.000 title 1
Classifications
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
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- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- AIDS & HIV (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17928400P | 2000-01-31 | 2000-01-31 | |
PCT/IB2001/000124 WO2001057036A1 (en) | 2000-01-31 | 2001-01-30 | Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of pde4 isozymes |
Publications (1)
Publication Number | Publication Date |
---|---|
IS6421A true IS6421A (is) | 2002-06-13 |
Family
ID=22655931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IS6421A IS6421A (is) | 2000-01-31 | 2002-06-13 | Nikótínamíð bensósambræddar-heterósýklýl afleiðurnytsamlegar sem valvísir latar á PDE4 samsætuensím |
Country Status (40)
Country | Link |
---|---|
US (1) | US7354941B2 (is) |
EP (1) | EP1252158B1 (is) |
JP (1) | JP3917863B2 (is) |
KR (1) | KR20020072299A (is) |
CN (1) | CN1404481A (is) |
AP (1) | AP2002002589A0 (is) |
AR (1) | AR027337A1 (is) |
AT (1) | ATE293624T1 (is) |
AU (1) | AU2700201A (is) |
BG (1) | BG106852A (is) |
BR (1) | BR0107964A (is) |
CA (1) | CA2398182C (is) |
CO (1) | CO5261634A1 (is) |
CZ (1) | CZ20022410A3 (is) |
DE (1) | DE60110205T2 (is) |
EA (1) | EA004885B1 (is) |
EE (1) | EE200200425A (is) |
ES (1) | ES2238415T3 (is) |
GE (1) | GEP20043302B (is) |
GT (1) | GT200100022A (is) |
HN (1) | HN2001000019A (is) |
HU (1) | HUP0204262A2 (is) |
IL (1) | IL150641A0 (is) |
IS (1) | IS6421A (is) |
MA (1) | MA26870A1 (is) |
MX (1) | MXPA02007419A (is) |
NO (1) | NO20023613L (is) |
NZ (1) | NZ519547A (is) |
OA (1) | OA12169A (is) |
PA (1) | PA8511201A1 (is) |
PE (1) | PE20011058A1 (is) |
PL (1) | PL357995A1 (is) |
PT (1) | PT1252158E (is) |
SK (1) | SK10142002A3 (is) |
SV (1) | SV2002000299A (is) |
TN (1) | TNSN01020A1 (is) |
TR (1) | TR200201880T2 (is) |
UY (1) | UY26569A1 (is) |
WO (1) | WO2001057036A1 (is) |
ZA (1) | ZA200206033B (is) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE457169T1 (de) * | 1998-10-15 | 2010-02-15 | Imp Innovations Ltd | Verbindungen für die behandlung von gewichtsverlust |
AU3467001A (en) * | 2000-01-28 | 2001-08-07 | Alza Corp | Liposomes containing an entrapped compound in supersaturated solution |
JP2004518629A (ja) | 2000-09-18 | 2004-06-24 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 殺菌・殺カビ剤として使用するためのピリジニルアミド類およびイミド類 |
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