YU58699A - - Google Patents

Info

Publication number
YU58699A
YU58699A YU58699A YU58699A YU58699A YU 58699 A YU58699 A YU 58699A YU 58699 A YU58699 A YU 58699A YU 58699 A YU58699 A YU 58699A YU 58699 A YU58699 A YU 58699A
Authority
YU
Yugoslavia
Application number
YU58699A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21959336&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU58699(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of YU58699A publication Critical patent/YU58699A/xx
Publication of RS49675B publication Critical patent/RS49675B/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
YUP-586/99A 1997-06-11 1998-05-29 4"supstituisani-9-deokso-9a-aza-9a- homoeritromicin a derivati RS49675B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4934897P 1997-06-11 1997-06-11
PCT/IB1998/000839 WO1998056802A1 (en) 1997-06-11 1998-05-29 4'-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Publications (2)

Publication Number Publication Date
YU58699A true YU58699A (es) 2002-08-12
RS49675B RS49675B (sr) 2007-11-15

Family

ID=21959336

Country Status (50)

Country Link
US (4) US6420536B1 (es)
EP (1) EP0988310B9 (es)
JP (2) JP3315704B2 (es)
KR (1) KR100396168B1 (es)
CN (4) CN101691390A (es)
AP (1) AP1231A (es)
AR (1) AR013086A1 (es)
AT (1) ATE251173T1 (es)
AU (1) AU749816B2 (es)
BG (1) BG64391B1 (es)
BR (1) BRPI9810519B8 (es)
CA (1) CA2293823C (es)
CO (1) CO4950611A1 (es)
CZ (1) CZ298556B6 (es)
DE (2) DE122004000018I2 (es)
DK (1) DK0988310T3 (es)
DZ (1) DZ2514A1 (es)
EA (1) EA002441B1 (es)
EG (1) EG24081A (es)
ES (1) ES2205487T3 (es)
FR (1) FR04C0013I2 (es)
GT (1) GT199800077A (es)
HK (3) HK1028048A1 (es)
HN (1) HN1998000086A (es)
HR (1) HRP980314B1 (es)
HU (2) HU228005B1 (es)
ID (1) ID22992A (es)
IL (1) IL132809A0 (es)
IS (1) IS1998B (es)
LU (1) LU91076I9 (es)
MA (1) MA24564A1 (es)
ME (1) ME00876B (es)
MY (1) MY123354A (es)
NL (1) NL300150I2 (es)
NO (1) NO316911B1 (es)
NZ (2) NZ514871A (es)
OA (1) OA11224A (es)
PA (1) PA8452201A1 (es)
PE (1) PE79699A1 (es)
PL (1) PL191601B1 (es)
PT (1) PT988310E (es)
RS (1) RS49675B (es)
SI (1) SI0988310T1 (es)
SK (1) SK284171B6 (es)
TN (1) TNSN98082A1 (es)
TW (1) TW472060B (es)
UA (1) UA67744C2 (es)
UY (1) UY25040A1 (es)
WO (1) WO1998056802A1 (es)
ZA (1) ZA985017B (es)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
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HN1998000086A (es) 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
EP1011689B8 (en) * 1997-09-10 2007-05-09 Merial Ltd. USE OF 9a-AZALIDES AS VETERINARY ANTIMICROBIAL AGENTS
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
EP1779853A3 (en) * 1997-09-10 2010-01-27 Merial Ltd. 9a-azalides as veterinary antimicrobial agents
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
EP1437360A3 (en) * 1998-08-19 2005-04-06 Pfizer Products Inc. C11 Carbamates of macrolide antibacterials
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
CA2292359C (en) * 1999-01-28 2004-09-28 Pfizer Products Inc. Novel azalides and methods of making same
OA11876A (en) * 1999-05-18 2006-03-27 Pfizer Prod Inc Novel crystalline forms of a macrolide antibiotic.
AU3832100A (en) * 1999-05-24 2000-12-12 Pfizer Products Inc. 13-methyl-erythromycin derivatives
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
US6764996B1 (en) 1999-08-24 2004-07-20 Abbott Laboratories 9a-azalides with antibacterial activity
PT1206476E (pt) * 1999-08-24 2006-05-31 Abbott Lab 9a-azalidos com actividade antibacteriana
US6608033B1 (en) 1999-08-27 2003-08-19 Pfizer Inc. Treatment or prevention of coccidiosis
ATE243703T1 (de) 2000-01-27 2003-07-15 Pfizer Prod Inc Antibiotische azalid-zusammensetzungen
PL359861A1 (en) * 2000-04-27 2004-09-06 Pfizer Products Inc. The use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals
RU2263117C2 (ru) * 2001-04-27 2005-10-27 Пфайзер Продактс Инк. Способ получения 4"-замещенных производных 9-деоксо-9а-аза-9а-гомоэритромицина а
AU2002317415A1 (en) * 2001-08-01 2003-02-17 Pfizer Products Inc. Azalide antibiotic compositions
CA2801100A1 (en) 2003-03-10 2004-09-23 Optimer Pharmaceuticals, Inc. Macrolides and processes for their preparation
US7276487B2 (en) 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
CA2546195A1 (en) * 2003-11-21 2005-06-02 Pfizer Products Inc. The use of anti biotics as vaccine adjuvants
CA2557801C (en) * 2004-03-16 2013-06-25 Boehringer Ingelheim International Gmbh Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
US7767797B1 (en) * 2004-09-30 2010-08-03 Synovo Gmbh Macrocyclic compounds and methods of use thereof
US7271155B2 (en) 2005-01-07 2007-09-18 Enanta Pharmaceuticals, Inc. 9A, 11-2C-bicyclic 9a-azalide derivatives
ATE429921T1 (de) * 2005-01-14 2009-05-15 Glaxosmithkline Zagreb 9a-carbamoyl- und thiocarbamoylazalide mit antimalariawirkung
CN105732745A (zh) 2007-10-25 2016-07-06 森普拉制药公司 大环内酯类抗菌剂的制备方法
CN107854477A (zh) 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en) * 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
WO2011032052A1 (en) 2009-09-10 2011-03-17 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
EP2550286B1 (en) 2010-03-22 2015-12-09 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
PL2571506T3 (pl) 2010-05-20 2017-10-31 Cempra Pharmaceuticals Inc Sposoby sporządzania makrolidów i ketolidów oraz ich produktów pośrednich
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
JP5908479B2 (ja) * 2010-09-20 2016-04-26 ノバルティス ティーアゲズントハイト アーゲー クラジノース環のC−4”をエポキシド基で修飾した9−デオキソ−9a−アザ−9a−ホモエリスロマイシンAの新規製造方法
EP2625185A4 (en) * 2010-10-10 2014-03-26 Synovo Gmbh INFLAMMATORY MAKROLIDE
CN102993250B (zh) * 2011-07-06 2016-02-10 洛阳惠中兽药有限公司 C-3取代的-9-脱氧-9a-氮杂-9a-高红霉素a衍生物
CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
EP2736915A1 (en) 2011-07-27 2014-06-04 Farma GRS, d.o.o. New crystalline forms of tulathromycin
IN2014DN08939A (es) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
EP2968384A4 (en) 2013-03-15 2017-02-15 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
SI3027634T1 (sl) * 2013-07-31 2018-10-30 Farma Grs, D.O.O. Proces za pripravo tulatromicina
CN103497227B (zh) * 2013-09-13 2015-09-30 青岛科技大学 一种泰拉菌素中间体的制备方法
CN104725446B (zh) * 2015-03-26 2017-10-27 宁夏泰瑞制药股份有限公司 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
CN104861018A (zh) * 2015-06-17 2015-08-26 瑞普(天津)生物药业有限公司 一种泰拉菌素的制备方法
CN105646617A (zh) * 2016-01-21 2016-06-08 杭州海尔希畜牧科技有限公司 一种制备泰拉霉素的方法
FR3048612B1 (fr) * 2016-03-14 2020-10-02 Septeos Tulathromycine potentialisee
CN106046077B (zh) * 2016-08-04 2019-07-26 湖北美天生物科技股份有限公司 一种泰拉霉素a的合成方法
CN108003207B (zh) * 2017-12-19 2019-05-10 海门慧聚药业有限公司 制备泰拉霉素的方法
CN111087433B (zh) * 2018-10-23 2023-03-21 湖北美天生物科技股份有限公司 一种泰拉霉素中间体的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
US5226958A (en) * 1991-04-11 1993-07-13 Pacemark, Inc. Sealant for pneumatic inner tubes and tubeless tires
EP0549040A1 (en) * 1991-12-20 1993-06-30 Merck & Co. Inc. Methods of making 4" derivatives of 9-deoxo-8a-aza-8a-alkyl-8a-homoerythromycin A
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
UA70972C2 (uk) 1998-11-20 2004-11-15 Пфайзер Продактс Інк. 13-членні азаліди і їх застосування як антибіотиків

Also Published As

Publication number Publication date
CN101691390A (zh) 2010-04-07
KR20010013632A (ko) 2001-02-26
ME00876B (me) 2012-06-20
RS49675B (sr) 2007-11-15
TNSN98082A1 (fr) 2005-03-15
NO996106L (no) 2000-02-10
US20020061858A1 (en) 2002-05-23
DE69818665D1 (de) 2003-11-06
AR013086A1 (es) 2000-12-13
HK1088014A1 (en) 2006-10-27
ZA985017B (en) 1999-12-17
JP3315704B2 (ja) 2002-08-19
LU91076I2 (fr) 2004-07-05
CN1259136A (zh) 2000-07-05
HU228005B1 (en) 2012-08-28
CO4950611A1 (es) 2000-09-01
BRPI9810519A (pt) 2000-09-19
CN1243766C (zh) 2006-03-01
BG103945A (en) 2000-07-31
US6420536B1 (en) 2002-07-16
ES2205487T3 (es) 2004-05-01
HN1998000086A (es) 1999-03-08
EP0988310B1 (en) 2003-10-01
LU91076I9 (en) 2018-07-02
CZ442199A3 (cs) 2000-07-12
UY25040A1 (es) 2000-09-29
PL191601B1 (pl) 2006-06-30
BRPI9810519B8 (pt) 2022-11-16
HRP980314A2 (en) 1999-04-30
IS5252A (is) 1999-11-16
DE122004000018I2 (de) 2011-01-13
IS1998B (is) 2005-03-15
HK1028048A1 (en) 2001-02-02
CA2293823C (en) 2004-02-17
CN1793155B (zh) 2010-05-12
US20040180842A1 (en) 2004-09-16
EP0988310A1 (en) 2000-03-29
DZ2514A1 (fr) 2003-02-01
EG24081A (en) 2008-05-11
AU749816B2 (en) 2002-07-04
CA2293823A1 (en) 1998-12-17
HRP980314B1 (en) 2004-04-30
MY123354A (en) 2006-05-31
AP1231A (en) 2003-12-11
KR100396168B1 (ko) 2003-08-27
JP2000514098A (ja) 2000-10-24
EA199901015A1 (ru) 2000-06-26
EP0988310B9 (en) 2006-03-08
PE79699A1 (es) 1999-08-25
SI0988310T1 (en) 2004-02-29
PL337505A1 (en) 2000-08-28
NZ514871A (en) 2003-08-29
AP9801255A0 (en) 1998-06-30
CN1566129A (zh) 2005-01-19
OA11224A (en) 2003-07-16
PT988310E (pt) 2003-12-31
EA002441B1 (ru) 2002-04-25
DK0988310T3 (da) 2003-12-15
US6777393B2 (en) 2004-08-17
ID22992A (id) 1999-12-23
IL132809A0 (en) 2001-03-19
BG64391B1 (bg) 2004-12-30
NL300150I1 (nl) 2004-08-02
CN1793155A (zh) 2006-06-28
SK284171B6 (sk) 2004-10-05
HUP0002209A3 (en) 2003-05-28
FR04C0013I1 (es) 2004-06-11
CN1172947C (zh) 2004-10-27
AU7347598A (en) 1998-12-30
HK1068893A1 (en) 2005-07-29
DE69818665T2 (de) 2004-04-29
CZ298556B6 (cs) 2007-11-07
MA24564A1 (fr) 1998-12-31
NL300150I2 (nl) 2004-09-01
ATE251173T1 (de) 2003-10-15
US20040023896A1 (en) 2004-02-05
HUS1200028I1 (hu) 2016-08-29
JP2002316933A (ja) 2002-10-31
US6936592B2 (en) 2005-08-30
UA67744C2 (uk) 2004-07-15
TW472060B (en) 2002-01-11
HUP0002209A2 (hu) 2000-12-28
BRPI9810519B1 (pt) 2012-02-22
NO996106D0 (no) 1999-12-10
DE122004000018I1 (de) 2004-09-30
FR04C0013I2 (es) 2005-10-21
PA8452201A1 (es) 2000-05-24
NZ500660A (en) 2002-03-01
WO1998056802A1 (en) 1998-12-17
NO316911B1 (no) 2004-06-21
SK168399A3 (en) 2000-11-07
GT199800077A (es) 1999-12-02

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