YU48290B - Postupak za proizvodnju novih acilala od derivata imidazol-5-karbonskih kiselina - Google Patents

Postupak za proizvodnju novih acilala od derivata imidazol-5-karbonskih kiselina

Info

Publication number
YU48290B
YU48290B YU87592A YU87592A YU48290B YU 48290 B YU48290 B YU 48290B YU 87592 A YU87592 A YU 87592A YU 87592 A YU87592 A YU 87592A YU 48290 B YU48290 B YU 48290B
Authority
YU
Yugoslavia
Prior art keywords
formula
compound
procedure
new
production
Prior art date
Application number
YU87592A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU87592A (sh
Inventor
D. Binder
J. Weinberger
Original Assignee
Chemisch Pharmazeutische Forschungsgesellschaft M.B.H.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemisch Pharmazeutische Forschungsgesellschaft M.B.H. filed Critical Chemisch Pharmazeutische Forschungsgesellschaft M.B.H.
Publication of YU87592A publication Critical patent/YU87592A/sh
Publication of YU48290B publication Critical patent/YU48290B/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
YU87592A 1991-10-04 1992-09-29 Postupak za proizvodnju novih acilala od derivata imidazol-5-karbonskih kiselina YU48290B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0198791A AT398202B (de) 1991-10-04 1991-10-04 Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
YU87592A YU87592A (sh) 1995-10-03
YU48290B true YU48290B (sh) 1998-05-15

Family

ID=3525398

Family Applications (1)

Application Number Title Priority Date Filing Date
YU87592A YU48290B (sh) 1991-10-04 1992-09-29 Postupak za proizvodnju novih acilala od derivata imidazol-5-karbonskih kiselina

Country Status (22)

Country Link
US (1) US5298519A (OSRAM)
EP (1) EP0535420A1 (OSRAM)
JP (1) JP2544565B2 (OSRAM)
CN (1) CN1032856C (OSRAM)
AT (1) AT398202B (OSRAM)
AU (1) AU649357B2 (OSRAM)
CA (1) CA2079735A1 (OSRAM)
CZ (1) CZ301992A3 (OSRAM)
FI (1) FI924353A7 (OSRAM)
HR (1) HRP920817A2 (OSRAM)
HU (1) HUT62291A (OSRAM)
IL (1) IL103329A (OSRAM)
LV (1) LV10256B (OSRAM)
MY (1) MY108350A (OSRAM)
NO (1) NO923798L (OSRAM)
NZ (1) NZ244320A (OSRAM)
RU (1) RU2105764C1 (OSRAM)
SI (1) SI9200240A (OSRAM)
SK (1) SK301992A3 (OSRAM)
TW (1) TW223073B (OSRAM)
YU (1) YU48290B (OSRAM)
ZA (1) ZA927205B (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2105939B1 (es) * 1994-08-02 1998-07-01 Uriach & Cia Sa J Nuevos pirazoles con actividad antagonista de la angiotensina ii.
SI1653950T1 (sl) * 2003-07-31 2008-06-30 Nicox Sa Nitrooksi derivati losartana, valsatana, kandesartana, telmisartana, eprosartana in olmesartana kotblokatorji receptorja angiotenzina-II za zdravljenje kardiovaskularnih bolezni
CN101024643A (zh) * 2006-02-20 2007-08-29 上海艾力斯医药科技有限公司 咪唑-5-羧酸类衍生物、制备方法及其应用
CN101195615B (zh) * 2006-12-06 2013-03-27 深圳市信立泰资产管理有限公司 咪唑-5-羧酸衍生物的盐、制备方法及其药物组合物
AU2006351517B8 (en) * 2006-12-06 2012-01-19 Shenzhen Salubris Pharmaceuticals Co., Ltd. The salts of imidazol-5-carboxylic acid derivatives, preparation methods and use thereof
CN101214242A (zh) * 2007-01-05 2008-07-09 上海艾力斯医药科技有限公司 新的药用组合物
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CN101317842A (zh) 2007-06-07 2008-12-10 上海艾力斯医药科技有限公司 一种咪唑-5-羧酸衍生物的治疗用途
CN101367795B (zh) * 2007-08-17 2012-05-02 上海艾力斯生物医药有限公司 一种咪唑-5-羧酸衍生物及其制备方法
CN101407511B (zh) * 2007-10-11 2013-01-09 上海艾力斯生物医药有限公司 一种结晶型的咪唑-5-羧酸衍生物
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN103012377A (zh) * 2011-09-27 2013-04-03 江苏艾力斯生物医药有限公司 一种咪唑-5-羧酸酯的重结晶方法
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
FI916130A7 (fi) * 1989-06-30 1991-12-27 Du Pont Aryylisubstituoituja imidatsoleja
DE69013607T2 (de) * 1989-08-02 1995-03-02 Takeda Chemical Industries Ltd Pyrazol-Derivate, Verfahren zu deren Herstellung und Anwendung.
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
PT573218E (pt) * 1992-06-02 2001-06-29 Sankyo Co 4-carbonilimidazoles como antagonistas de angiotensina ii e sua utilizacao terapeutica

Also Published As

Publication number Publication date
RU2105764C1 (ru) 1998-02-27
FI924353L (fi) 1993-04-05
CA2079735A1 (en) 1993-04-05
IL103329A (en) 1996-10-31
TW223073B (OSRAM) 1994-05-01
JPH05310731A (ja) 1993-11-22
HUT62291A (en) 1993-04-28
AT398202B (de) 1994-10-25
FI924353A7 (fi) 1993-04-05
NZ244320A (en) 1995-01-27
SI9200240A (en) 1993-06-30
YU87592A (sh) 1995-10-03
NO923798D0 (no) 1992-09-30
CZ301992A3 (en) 1993-08-11
HRP920817A2 (en) 1996-08-31
EP0535420A1 (de) 1993-04-07
LV10256A (lv) 1994-10-20
SK301992A3 (en) 1995-10-11
CN1071426A (zh) 1993-04-28
MY108350A (en) 1996-09-30
HU9203149D0 (en) 1992-12-28
US5298519A (en) 1994-03-29
IL103329A0 (en) 1993-03-15
CN1032856C (zh) 1996-09-25
AU2617692A (en) 1993-04-08
FI924353A0 (fi) 1992-09-29
NO923798L (no) 1993-04-05
ATA198791A (de) 1994-02-15
LV10256B (en) 1995-04-20
ZA927205B (en) 1993-03-23
AU649357B2 (en) 1994-05-19
JP2544565B2 (ja) 1996-10-16

Similar Documents

Publication Publication Date Title
YU48290B (sh) Postupak za proizvodnju novih acilala od derivata imidazol-5-karbonskih kiselina
DE3272792D1 (en) Process for the preparation of 2-penem compounds
ES8607914A1 (es) Un procedimiento de preparar un derivado de trans-1,2-diaminociclohexil-amida.
DK0567271T3 (da) Steroidderivater til behandling af prostatahypertrofi, fremgangsmåde til fremstilling heraf og anvendelser heraf
ES8800207A1 (es) Un procedimiento para producir derivados de 3(2h)-piridazinona.
TWI367882B (en) Preparation and use of 2-substituted-5-oxo-3-pyrazolidinecarboxylates
GEP19970786B (en) Method of n-/2-/4-fluorphenyl/-1-methyl-ethyl-n-methyl-n-propinylamine production
YU47943B (sh) Etri 1-benzil-3-hidroksimetil-indazola sa alifatičnim 2-hidroksi kiselinama i postupak dobijanja
YU46696B (sh) Postupak za dobijanje oksoftalazinil sirćetnih kiselina koje imaju benzotiazolne ili druge heterociklične bočne nizove
GB1554075A (en) 1,2-dihydro-3h-pyrrolo-(1,2-a)-pyrrole-1-carboxylic acid derivatives and process for the production thereof
YU45810B (sh) Postupak za dobijanje hinolin karboksilnih kiselina
ES8609195A1 (es) Un nuevo procedimiento para la preparacion de derivados del acido cicloalquilidenmetilfenilacetico.
YU46570B (sh) Postupak za dobivanje derivata hinolin karboksilne kiseline
KR880006239A (ko) 기라제 억제제, 그의 제조방법 및 용도
ES487175A1 (es) Un procedimiento de preparacion de derivados de piperi- dil-indol
MY104238A (en) Prodrugs of antiinflammatory 3-acyl-2-oxindole-1 -carboxamides.
ES474545A1 (es) Un procedimiento de preparacion,en todas sus formas estereo-isomeras o en forma de mezclas de estereoisomeras,de esteresde alcoholes hologenados
NO306942B1 (no) Nye derivater av ester av karboksylsyre, samt insekticid og insektbekjempende middel inneholdende disse
JPS53108933A (en) Production of amidinoformic acid derivative
FR2476649B1 (OSRAM)
JPS5573677A (en) Thienylbenzoic acid derivative and its production
JPS5515460A (en) Novel 2-substituted-benzoylpropionic acid derivative
HUT45996A (en) Process for producing 4-morpholinyl-1h-indole derivatives and pharmaceutics comprising same
GB1045544A (en) New derivatives of pyrazolidines their production and use
GB1003478A (en) 8-hydroxy-quinoline derivatives