LV10256A - Jauni acilali no imidazol-5-karbonskabju atvasinajumiem to iegusanas panemiens un pielietojums - Google Patents

Jauni acilali no imidazol-5-karbonskabju atvasinajumiem to iegusanas panemiens un pielietojums

Info

Publication number
LV10256A
LV10256A LV920142A LV920142A LV10256A LV 10256 A LV10256 A LV 10256A LV 920142 A LV920142 A LV 920142A LV 920142 A LV920142 A LV 920142A LV 10256 A LV10256 A LV 10256A
Authority
LV
Latvia
Prior art keywords
acylals
imidazole
saturation
new
application
Prior art date
Application number
LV920142A
Other languages
English (en)
Other versions
LV10256B (en
Inventor
Dieter Dr Binder
Josef Dr Weinberger
Original Assignee
Chem Pharm Forsch Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Pharm Forsch Gmbh filed Critical Chem Pharm Forsch Gmbh
Publication of LV10256A publication Critical patent/LV10256A/lv
Publication of LV10256B publication Critical patent/LV10256B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LVP-92-142A 1991-10-04 1992-10-01 Novel acylale of imidazole-5-carboxylic acid derivatives, process for producing thereof and using same LV10256B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0198791A AT398202B (de) 1991-10-04 1991-10-04 Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
LV10256A true LV10256A (lv) 1994-10-20
LV10256B LV10256B (en) 1995-04-20

Family

ID=3525398

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-92-142A LV10256B (en) 1991-10-04 1992-10-01 Novel acylale of imidazole-5-carboxylic acid derivatives, process for producing thereof and using same

Country Status (22)

Country Link
US (1) US5298519A (lv)
EP (1) EP0535420A1 (lv)
JP (1) JP2544565B2 (lv)
CN (1) CN1032856C (lv)
AT (1) AT398202B (lv)
AU (1) AU649357B2 (lv)
CA (1) CA2079735A1 (lv)
CZ (1) CZ301992A3 (lv)
FI (1) FI924353A (lv)
HR (1) HRP920817A2 (lv)
HU (1) HUT62291A (lv)
IL (1) IL103329A (lv)
LV (1) LV10256B (lv)
MY (1) MY108350A (lv)
NO (1) NO923798L (lv)
NZ (1) NZ244320A (lv)
RU (1) RU2105764C1 (lv)
SI (1) SI9200240A (lv)
SK (1) SK301992A3 (lv)
TW (1) TW223073B (lv)
YU (1) YU48290B (lv)
ZA (1) ZA927205B (lv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2105939B1 (es) * 1994-08-02 1998-07-01 Uriach & Cia Sa J Nuevos pirazoles con actividad antagonista de la angiotensina ii.
CN101024643A (zh) 2006-02-20 2007-08-29 上海艾力斯医药科技有限公司 咪唑-5-羧酸类衍生物、制备方法及其应用
CN101195615B (zh) * 2006-12-06 2013-03-27 深圳市信立泰资产管理有限公司 咪唑-5-羧酸衍生物的盐、制备方法及其药物组合物
KR101112515B1 (ko) * 2006-12-06 2012-02-24 상하이 알리스트 파마슈티컬즈 인코포레이티드 이미다졸-5- 카복실산 유도체의 염 및 그 제조방법 및 상기 염으로 구성되는 약학 조성물
CN101214242A (zh) * 2007-01-05 2008-07-09 上海艾力斯医药科技有限公司 新的药用组合物
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CN101317842A (zh) * 2007-06-07 2008-12-10 上海艾力斯医药科技有限公司 一种咪唑-5-羧酸衍生物的治疗用途
CN101367795B (zh) * 2007-08-17 2012-05-02 上海艾力斯生物医药有限公司 一种咪唑-5-羧酸衍生物及其制备方法
CN101407511B (zh) * 2007-10-11 2013-01-09 上海艾力斯生物医药有限公司 一种结晶型的咪唑-5-羧酸衍生物
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN103012377A (zh) * 2011-09-27 2013-04-03 江苏艾力斯生物医药有限公司 一种咪唑-5-羧酸酯的重结晶方法
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
AU645022B2 (en) * 1989-06-30 1994-01-06 E.I. Du Pont De Nemours And Company Fused-ring aryl substituted imidazoles
ATE113281T1 (de) * 1989-08-02 1994-11-15 Takeda Chemical Industries Ltd Pyrazol-derivate, verfahren zu deren herstellung und anwendung.
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
ATE199548T1 (de) * 1992-06-02 2001-03-15 Sankyo Co 4-carboxyimidazolderivate als angiotensin-ii- antagonisten und ihre therapeutische verwendung

Also Published As

Publication number Publication date
ZA927205B (en) 1993-03-23
LV10256B (en) 1995-04-20
CA2079735A1 (en) 1993-04-05
YU87592A (sh) 1995-10-03
NO923798L (no) 1993-04-05
HRP920817A2 (en) 1996-08-31
FI924353A (fi) 1993-04-05
JPH05310731A (ja) 1993-11-22
AU2617692A (en) 1993-04-08
RU2105764C1 (ru) 1998-02-27
AT398202B (de) 1994-10-25
IL103329A0 (en) 1993-03-15
EP0535420A1 (de) 1993-04-07
ATA198791A (de) 1994-02-15
HUT62291A (en) 1993-04-28
NO923798D0 (no) 1992-09-30
CZ301992A3 (en) 1993-08-11
JP2544565B2 (ja) 1996-10-16
SK301992A3 (en) 1995-10-11
MY108350A (en) 1996-09-30
SI9200240A (en) 1993-06-30
FI924353A0 (fi) 1992-09-29
IL103329A (en) 1996-10-31
TW223073B (lv) 1994-05-01
CN1032856C (zh) 1996-09-25
US5298519A (en) 1994-03-29
AU649357B2 (en) 1994-05-19
NZ244320A (en) 1995-01-27
HU9203149D0 (en) 1992-12-28
YU48290B (sh) 1998-05-15
CN1071426A (zh) 1993-04-28

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