FR2476649B1 - - Google Patents

Info

Publication number
FR2476649B1
FR2476649B1 FR8004198A FR8004198A FR2476649B1 FR 2476649 B1 FR2476649 B1 FR 2476649B1 FR 8004198 A FR8004198 A FR 8004198A FR 8004198 A FR8004198 A FR 8004198A FR 2476649 B1 FR2476649 B1 FR 2476649B1
Authority
FR
France
Prior art keywords
carbon atoms
group
hydrogen
alkyl
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8004198A
Other languages
English (en)
French (fr)
Other versions
FR2476649A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR8004198A priority Critical patent/FR2476649A1/fr
Priority to EP81400272A priority patent/EP0034546B1/fr
Priority to EP81400273A priority patent/EP0034989B1/fr
Priority to ZA00811149A priority patent/ZA811149B/xx
Priority to AT81400272T priority patent/ATE7498T1/de
Priority to DE8181400273T priority patent/DE3161072D1/de
Priority to AT81400273T priority patent/ATE4896T1/de
Priority to DE8181400272T priority patent/DE3163567D1/de
Priority to FI810544A priority patent/FI71554C/fi
Priority to US06/237,062 priority patent/US4313944A/en
Priority to US06/236,610 priority patent/US4335135A/en
Priority to GR64231A priority patent/GR73816B/el
Priority to AU67603/81A priority patent/AU539662B2/en
Priority to HU81457A priority patent/HU183345B/hu
Priority to CA000371721A priority patent/CA1161038A/fr
Priority to ES499771A priority patent/ES499771A0/es
Priority to PT72567A priority patent/PT72567B/pt
Priority to CA000371728A priority patent/CA1161444A/fr
Priority to JP2621281A priority patent/JPS56133292A/ja
Priority to JP2621381A priority patent/JPS56133266A/ja
Publication of FR2476649A1 publication Critical patent/FR2476649A1/fr
Application granted granted Critical
Publication of FR2476649B1 publication Critical patent/FR2476649B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR8004198A 1980-02-26 1980-02-26 Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant Granted FR2476649A1 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
FR8004198A FR2476649A1 (fr) 1980-02-26 1980-02-26 Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
EP81400273A EP0034989B1 (fr) 1980-02-26 1981-02-20 Nouveaux dérivés du cycloheptindolol et leurs sels avec les acides, leur préparation, leur application comme médicaments et les compositions les renfermant
ZA00811149A ZA811149B (en) 1980-02-26 1981-02-20 Cyclohepitindolol derivatives and their salts with the acids, their preparation, their use as medicaments and the compositions containing them
AT81400272T ATE7498T1 (de) 1980-02-26 1981-02-20 Cycloheptindolderivate und ihre saeureadditionssalze, ihre herstellung, ihre verwendung als arzneimittel und sie enthaltende zusammensetzungen.
DE8181400273T DE3161072D1 (en) 1980-02-26 1981-02-20 Cycloheptindolol derivatives and their acid-addition salts, their preparation, their use as medicines and composition containing them
AT81400273T ATE4896T1 (de) 1980-02-26 1981-02-20 Cycloheptindolol-derivate und ihre salze mit saeuren, ihre herstellung, verwendung als heilmittel und zusammensetzungen, die sie enthalten.
DE8181400272T DE3163567D1 (en) 1980-02-26 1981-02-20 Cycloheptindole derivatives and their acid-addition salts, their preparation, their use as medicaments and compositions containing them
EP81400272A EP0034546B1 (fr) 1980-02-26 1981-02-20 Nouveaux dérivés du cycloheptindole et leurs sels d'addition avec les acides, leur préparation, leur application comme médicaments et les compositions les renfermant
US06/236,610 US4335135A (en) 1980-02-26 1981-02-23 5 Amino-3,4,5,6 tetrahydro-1H-[-6-]cyclohept[c,d]indolols and a method for their use as hypotensives
US06/237,062 US4313944A (en) 1980-02-26 1981-02-23 Cycloheptindoles, compositions and use
FI810544A FI71554C (fi) 1980-02-26 1981-02-23 Foerfarande foer framstaellning av terapeutiskt anvaendbara 5-r,s-trans-amino-3,4,5,6-tetrahydro-1h -cyklohept/c,d/indol-6-olderivat och av deras syraadditionssalter.
AU67603/81A AU539662B2 (en) 1980-02-26 1981-02-24 Cycloheptindolol derivatives
GR64231A GR73816B (OSRAM) 1980-02-26 1981-02-24
CA000371721A CA1161038A (fr) 1980-02-26 1981-02-25 Procede de preparation de nouveaux derives du cycloheptindole et de ses sels avec les acides
HU81457A HU183345B (en) 1980-02-26 1981-02-25 Process for producing cycloheptindolol derivatives
ES499771A ES499771A0 (es) 1980-02-26 1981-02-25 Un procedimiento para preparar derivados de cicloheptilindo-lol
PT72567A PT72567B (fr) 1980-02-26 1981-02-25 Procede de preparation de derives du cyclohepindolol et de leurs sels avec les acides
CA000371728A CA1161444A (fr) 1980-02-26 1981-02-25 Procede de preparation de derives du cycloheptindolol et de leurs sels avec les acides
JP2621281A JPS56133292A (en) 1980-02-26 1981-02-26 Novel derivatives of cycloheptoindole, salts with their acids, their manufacture, application as drug and composition containing them
JP2621381A JPS56133266A (en) 1980-02-26 1981-02-26 Novel derivative of cycloheptoindole, salt with acid of same, manufacture, application as drug and composition containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8004198A FR2476649A1 (fr) 1980-02-26 1980-02-26 Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Publications (2)

Publication Number Publication Date
FR2476649A1 FR2476649A1 (fr) 1981-08-28
FR2476649B1 true FR2476649B1 (OSRAM) 1982-03-05

Family

ID=9238981

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8004198A Granted FR2476649A1 (fr) 1980-02-26 1980-02-26 Nouveaux derives du cycloheptindole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Country Status (8)

Country Link
US (1) US4313944A (OSRAM)
EP (1) EP0034546B1 (OSRAM)
JP (2) JPS56133266A (OSRAM)
AT (1) ATE7498T1 (OSRAM)
CA (1) CA1161038A (OSRAM)
DE (1) DE3163567D1 (OSRAM)
FR (1) FR2476649A1 (OSRAM)
ZA (1) ZA811149B (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2479830A1 (fr) * 1980-04-03 1981-10-09 Roussel Uclaf Nouveaux derives de l'indolobenzoxazine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
US4349548A (en) * 1981-11-20 1982-09-14 Merck & Co., Inc. Octahydrobenzo[6,7]cyclohept[1,2-b]-1,4-oxazines, compositions and use
FR2533215A1 (fr) * 1982-09-20 1984-03-23 Roussel Uclaf Nouveaux derives de la c-homo 9-oxaergoline, leurs sels, procede de preparation et intermediaires de preparation, application a titre de medicaments et compositions les renfermant
FR2594828B1 (fr) * 1986-02-24 1988-07-01 Roussel Uclaf Derives du tetrahydrobenz (c,d) indole, leurs sels, procede de preparation, application a titre de medicaments, compositions les renfermant et intermediaires

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4238486A (en) * 1979-11-23 1980-12-09 Merck & Co., Inc. Indolobenzoxazines

Also Published As

Publication number Publication date
US4313944A (en) 1982-02-02
ZA811149B (en) 1982-03-31
DE3163567D1 (en) 1984-06-20
JPH0148268B2 (OSRAM) 1989-10-18
JPS56133292A (en) 1981-10-19
CA1161038A (fr) 1984-01-24
ATE7498T1 (de) 1984-06-15
EP0034546B1 (fr) 1984-05-16
EP0034546A1 (fr) 1981-08-26
JPS56133266A (en) 1981-10-19
FR2476649A1 (fr) 1981-08-28

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Legal Events

Date Code Title Description
ST Notification of lapse