ES458309A1 - Procedimiento de preparacion de nuevos derivados de 1,4-ben-zodioxano. - Google Patents

Procedimiento de preparacion de nuevos derivados de 1,4-ben-zodioxano.

Info

Publication number
ES458309A1
ES458309A1 ES458309A ES458309A ES458309A1 ES 458309 A1 ES458309 A1 ES 458309A1 ES 458309 A ES458309 A ES 458309A ES 458309 A ES458309 A ES 458309A ES 458309 A1 ES458309 A1 ES 458309A1
Authority
ES
Spain
Prior art keywords
novel
hydrogen
benzodioxanes
carbon atoms
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES458309A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES458309A1 publication Critical patent/ES458309A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

Procedimiento de preparación de nuevos derivados de 1,4-benzodioxano de fórmula I¿: (*ver imagen I¿), en la que R¿ representa un átomo de hidrógeno, un radical alcoxi que contiene de 1 a 5 átomos de carbono, o un átomo de cloro, bromo o flúor.
ES458309A 1976-04-30 1977-04-29 Procedimiento de preparacion de nuevos derivados de 1,4-ben-zodioxano. Expired ES458309A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7612941A FR2349331A1 (fr) 1976-04-30 1976-04-30 Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES458309A1 true ES458309A1 (es) 1978-02-16

Family

ID=9172538

Family Applications (1)

Application Number Title Priority Date Filing Date
ES458309A Expired ES458309A1 (es) 1976-04-30 1977-04-29 Procedimiento de preparacion de nuevos derivados de 1,4-ben-zodioxano.

Country Status (18)

Country Link
US (1) US4100291A (es)
JP (1) JPS52133992A (es)
AU (1) AU506408B2 (es)
BE (1) BE854112A (es)
CA (1) CA1095047A (es)
CH (1) CH602711A5 (es)
DE (1) DE2719294A1 (es)
DK (1) DK187577A (es)
ES (1) ES458309A1 (es)
FR (1) FR2349331A1 (es)
GB (1) GB1542361A (es)
HU (1) HU172529B (es)
IL (1) IL51974A (es)
LU (1) LU77241A1 (es)
NL (1) NL7704759A (es)
SE (1) SE7704615L (es)
SU (1) SU700063A3 (es)
ZA (1) ZA772601B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR2420536A1 (fr) * 1978-03-22 1979-10-19 Roussel Uclaf Nouveaux derives de 1,3-dihydro 3-/1-/2-(2,3-dihydro 1,4-benzodioxin-2-yl)2-hydroxyethyl/piperidin-4-yl/2h-indol-2-one, procede pour leur preparation et application comme medicaments
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels
DE3035403C2 (de) 1980-09-19 1982-08-26 Rütgerswerke AG, 6000 Frankfurt Verfahren zur Herstellung von 5-Chlorindol
FR2533924A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
DE4414113A1 (de) * 1994-04-22 1995-10-26 Merck Patent Gmbh 3-Indolylpiperidine
AU747508B2 (en) * 1998-03-19 2002-05-16 Nihon Nohyaku Co., Ltd. Arylpiperidine derivatives and use thereof
AU2006306497A1 (en) * 2005-10-24 2007-05-03 Janssen Pharmaceutica, N.V. 3-piperidin-4-yl-indole ORL-1 receptor modulators

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2193584B1 (es) * 1972-07-28 1975-08-08 Roussel Uclaf
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
US3914238A (en) * 1974-01-18 1975-10-21 Janssen Pharmaceutica Nv 4-Aryl-{60 -(1,4-benzodioxan-2-yl)-4-hydroxy-1-piperidineethanols
US4039676A (en) * 1975-06-23 1977-08-02 Ciba-Geigy Corporation 2-piperidinoalkyl-1,4-benzodioxans

Also Published As

Publication number Publication date
JPS52133992A (en) 1977-11-09
CH602711A5 (es) 1978-07-31
ZA772601B (en) 1978-09-27
NL7704759A (nl) 1977-11-01
HU172529B (hu) 1978-09-28
IL51974A (en) 1980-09-16
IL51974A0 (en) 1977-06-30
FR2349331A1 (fr) 1977-11-25
DK187577A (da) 1977-10-31
GB1542361A (en) 1979-03-14
AU2470977A (en) 1978-11-02
LU77241A1 (es) 1977-12-13
DE2719294A1 (de) 1977-11-17
SE7704615L (sv) 1977-10-31
FR2349331B1 (es) 1978-08-25
SU700063A3 (ru) 1979-11-25
BE854112A (fr) 1977-10-31
AU506408B2 (en) 1980-01-03
CA1095047A (fr) 1981-02-03
US4100291A (en) 1978-07-11

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