ES461875A1 - Procedimiento de preparacion de nuevos derivados del piperi-dil-indol. - Google Patents

Procedimiento de preparacion de nuevos derivados del piperi-dil-indol.

Info

Publication number
ES461875A1
ES461875A1 ES461875A ES461875A ES461875A1 ES 461875 A1 ES461875 A1 ES 461875A1 ES 461875 A ES461875 A ES 461875A ES 461875 A ES461875 A ES 461875A ES 461875 A1 ES461875 A1 ES 461875A1
Authority
ES
Spain
Prior art keywords
indoles
piperidyl
psychic disorders
hydrogen
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES461875A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES461875A1 publication Critical patent/ES461875A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/10—Succinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Procedimiento de preparación de nuevos derivados del piperidil-indol, y de sus sales de adición con ácidos minerales u orgánicos, respondiendo dichos derivados a la fórmula general I. *(ver fórmula I)*.
ES461875A 1976-08-26 1977-08-25 Procedimiento de preparacion de nuevos derivados del piperi-dil-indol. Expired ES461875A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7625798A FR2362628A1 (fr) 1976-08-26 1976-08-26 Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments

Publications (1)

Publication Number Publication Date
ES461875A1 true ES461875A1 (es) 1978-05-16

Family

ID=9177152

Family Applications (1)

Application Number Title Priority Date Filing Date
ES461875A Expired ES461875A1 (es) 1976-08-26 1977-08-25 Procedimiento de preparacion de nuevos derivados del piperi-dil-indol.

Country Status (19)

Country Link
US (1) US4196209A (es)
JP (1) JPS5328178A (es)
AT (1) AT358582B (es)
AU (1) AU510037B2 (es)
BE (1) BE858101A (es)
CA (1) CA1103676A (es)
CH (2) CH624952A5 (es)
DE (1) DE2738646C2 (es)
DK (1) DK142812B (es)
ES (1) ES461875A1 (es)
FR (1) FR2362628A1 (es)
GB (1) GB1556919A (es)
HU (1) HU172711B (es)
IE (1) IE45574B1 (es)
LU (1) LU78028A1 (es)
NL (1) NL7709383A (es)
PT (1) PT66953B (es)
SE (1) SE432595B (es)
ZA (1) ZA775134B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2421899A1 (fr) * 1978-01-16 1979-11-02 Roussel Uclaf Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels
SE8004129L (sv) * 1979-07-13 1981-01-14 Roussel Uclaf Nya tetrahydropyridin-4-yl-indolderivat samt salter derav, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar
FR2460947A1 (fr) * 1979-07-13 1981-01-30 Roussel Uclaf Nouveau derives n-substitues du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
DE3035403C2 (de) 1980-09-19 1982-08-26 Rütgerswerke AG, 6000 Frankfurt Verfahren zur Herstellung von 5-Chlorindol
FR2510111A1 (fr) * 1981-07-24 1983-01-28 Roussel Uclaf Nouveaux derives du piperidin-3-yl indole, leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
IE55972B1 (en) * 1982-10-07 1991-03-13 Kefalas As Phenylindene derivatives,acid addition salts thereof,and methods of preparation
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
FR2608157B1 (fr) * 1986-12-11 1989-09-08 Roussel Uclaf Nouveaux derives de l'azaspirodecane, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant et intermediaires
EP0303507B1 (en) * 1987-08-13 1993-07-28 Glaxo Group Limited Indole derivatives
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
FR2621586B1 (fr) * 1987-10-08 1990-02-02 Roussel Uclaf Nouveaux derives de l'azapirodecane, leur procede de preparation et leur application comme medicaments
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
WO1990007926A1 (en) * 1989-01-20 1990-07-26 Pfizer Inc. 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
DK36291D0 (da) * 1991-03-01 1991-03-01 Lundbeck & Co As H Anvendelse af piperidylsubstituerede indolderivater til behandling af kognitive lidelser
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
ES2292636T3 (es) * 2000-11-29 2008-03-16 Eli Lilly And Company 1-(2-m-metanosulfanomidofeniletil)-4-(m-trifluorometilfenil)piper.
WO2004069828A1 (ja) * 2003-02-04 2004-08-19 Mitsubishi Pharma Corporation ピペリジン化合物およびその医薬用途
JP2009515833A (ja) * 2005-10-24 2009-04-16 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ３−ピペリジン−４−イル−インドールｏｒｌ−１受容体モジュレーター

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872453A (en) * 1959-02-03 Indole derivatives
US3361759A (en) * 1963-10-07 1968-01-02 Upjohn Co 3-(2-pyrrolidinyl)-indoles and method of preparation
JPS4856687A (es) * 1971-11-18 1973-08-09
FR2193584B1 (es) * 1972-07-28 1975-08-08 Roussel Uclaf
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2258843B1 (es) * 1974-01-30 1977-09-09 Roussel Uclaf
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
FR2349331A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments

Also Published As

Publication number Publication date
ZA775134B (en) 1978-09-27
JPS5328178A (en) 1978-03-16
GB1556919A (en) 1979-11-28
BE858101A (fr) 1978-02-27
JPS631312B2 (es) 1988-01-12
HU172711B (hu) 1978-11-28
DE2738646A1 (de) 1978-03-02
IE45574L (en) 1978-02-26
CH628344A5 (fr) 1982-02-26
ATA619677A (de) 1980-02-15
DK142812B (da) 1981-02-02
FR2362628B1 (es) 1979-03-02
LU78028A1 (es) 1978-04-27
PT66953B (fr) 1979-11-12
DK142812C (es) 1981-09-21
SE432595B (sv) 1984-04-09
FR2362628A1 (fr) 1978-03-24
SE7707731L (sv) 1978-02-27
DK376577A (es) 1978-02-27
AT358582B (de) 1980-09-25
DE2738646C2 (de) 1985-08-08
AU510037B2 (en) 1980-06-05
CH624952A5 (es) 1981-08-31
US4196209A (en) 1980-04-01
AU2821377A (en) 1979-03-01
IE45574B1 (en) 1982-10-06
CA1103676A (fr) 1981-06-23
PT66953A (fr) 1977-09-01
NL7709383A (nl) 1978-02-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201