ES8103742A2 - Un procedimiento de preparacion de nuevos derivados de 1,3-benzodioxina - Google Patents
Un procedimiento de preparacion de nuevos derivados de 1,3-benzodioxinaInfo
- Publication number
- ES8103742A2 ES8103742A2 ES480137A ES48013779A ES8103742A2 ES 8103742 A2 ES8103742 A2 ES 8103742A2 ES 480137 A ES480137 A ES 480137A ES 48013779 A ES48013779 A ES 48013779A ES 8103742 A2 ES8103742 A2 ES 8103742A2
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- carbon atoms
- group
- alkyl
- dialkylaminoalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/08—1,3-Dioxanes; Hydrogenated 1,3-dioxanes condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/24—Halogenated derivatives
- C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE DERIVADOS DE 1,3-BENZODIOXINA (CERTIFICADO DE ADICION NUM. 463.842). EL COMPUESTO QUE SE DESEA PREPARAR ES EL 6-CLORO-4-METIL-4-FENIL (4H) 1,3-BEZO-DIOXIN-2-CARBOXILATO DE 2-DIMETILAMINOETILO EN SUS FORMAS RACEMICAS Y OPTICAMENTE ACTIVAS, ASI COMO SUS SALES DE ADICION CON ACIDOS. ESTE COMPUESTO SE OBTIENE HACIENDO REACCIONAR ACIDO 6-CLORO-4-METILO-4-FENIL (4H) 1,3-BENZODIOXIN-2-CARBOXILICO CON DIMETILAMINOETANOL, EN EL SENO DE UN DISOLVENTE ORGANICO TAL COMO BENCENO, TOLUENO, XILENO O ETER ETILICO, EN PRESENCIA DE UN CATALIZADOR Y A UNA TEMPERATURA DE REACCION QUE VA DESDE -10GC HASTA LA TEMPERATURA DE REFLUJO DEL MEDIO DE REACCION. EL COMPUESTO OBTENIDO TIENE APLICACION EN LA INSUFICIENCIA CARDIACA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7813094A FR2424914A2 (fr) | 1978-05-03 | 1978-05-03 | Nouveaux derives de (1-3) benzodioxine, un procede pour leur preparation et leur application comme medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES480137A0 ES480137A0 (es) | 1981-03-16 |
| ES8103742A2 true ES8103742A2 (es) | 1981-03-16 |
Family
ID=9207866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES480137A Expired ES8103742A2 (es) | 1978-05-03 | 1979-05-02 | Un procedimiento de preparacion de nuevos derivados de 1,3-benzodioxina |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4294845A (es) |
| JP (1) | JPS54144381A (es) |
| AT (1) | AT363933B (es) |
| BE (1) | BE875985R (es) |
| DE (1) | DE2917901A1 (es) |
| ES (1) | ES8103742A2 (es) |
| FR (1) | FR2424914A2 (es) |
| GB (1) | GB2020285B (es) |
| IE (1) | IE48224B1 (es) |
| IT (1) | IT1164677B (es) |
| LU (1) | LU81210A1 (es) |
| NL (1) | NL7903439A (es) |
| ZA (1) | ZA791887B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9016799D0 (en) * | 1990-07-31 | 1990-09-12 | Shell Int Research | Pesticidal heterocyclic compounds |
| KR100366355B1 (ko) * | 1997-04-30 | 2005-12-21 | 주식회사 엘지생명과학 | 치환된 5-히드록시-4h-(1,3)-벤조디옥신-4-온 유도체 및 그의 제조방법 |
| AU2013261719B2 (en) * | 2012-05-18 | 2017-07-27 | Sanofi | Benzo[1,3]dioxine derivatives and their use as LPAR5 antagonists |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1312893A (fr) * | 1962-01-29 | 1962-12-21 | Geigy Ag J R | Nouveaux amides d'acides 1.4-benzodioxanne-carboxyliques et leur préparation |
| US3836543A (en) * | 1970-10-14 | 1974-09-17 | Richardson Merrell Inc | Method of preparing dibenzo(d,g)(1,3)dioxocin acids and salts thereof |
| FR2146895B1 (es) * | 1971-07-23 | 1974-09-06 | Crt | |
| BE806220A (fr) * | 1972-10-20 | 1974-02-15 | Luso Farmaco Inst | Nouveaux esters et amides d'acides 3-aryl-1,4-benzodioxanne- 2-ylcarboxyliques |
| US4056540A (en) * | 1974-01-01 | 1977-11-01 | Bristol-Myers Company | 4-Phenyl-1,3-benzodioxans |
-
1978
- 1978-05-03 FR FR7813094A patent/FR2424914A2/fr active Granted
-
1979
- 1979-04-20 ZA ZA791887A patent/ZA791887B/xx unknown
- 1979-04-30 US US06/034,431 patent/US4294845A/en not_active Expired - Lifetime
- 1979-05-02 LU LU81210A patent/LU81210A1/xx unknown
- 1979-05-02 NL NL7903439A patent/NL7903439A/xx not_active Application Discontinuation
- 1979-05-02 JP JP5352179A patent/JPS54144381A/ja active Pending
- 1979-05-02 BE BE0/194946A patent/BE875985R/xx not_active IP Right Cessation
- 1979-05-02 IT IT48907/79A patent/IT1164677B/it active
- 1979-05-02 ES ES480137A patent/ES8103742A2/es not_active Expired
- 1979-05-03 GB GB7915446A patent/GB2020285B/en not_active Expired
- 1979-05-03 DE DE19792917901 patent/DE2917901A1/de not_active Withdrawn
- 1979-05-03 AT AT0333379A patent/AT363933B/de not_active IP Right Cessation
- 1979-08-08 IE IE924/79A patent/IE48224B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA791887B (en) | 1980-08-27 |
| AT363933B (de) | 1981-09-10 |
| NL7903439A (nl) | 1979-11-06 |
| LU81210A1 (fr) | 1979-12-06 |
| BE875985R (fr) | 1979-11-05 |
| ATA333379A (de) | 1981-02-15 |
| GB2020285A (en) | 1979-11-14 |
| JPS54144381A (en) | 1979-11-10 |
| GB2020285B (en) | 1982-09-02 |
| DE2917901A1 (de) | 1979-11-15 |
| US4294845A (en) | 1981-10-13 |
| ES480137A0 (es) | 1981-03-16 |
| IT1164677B (it) | 1987-04-15 |
| FR2424914A2 (fr) | 1979-11-30 |
| IT7948907A0 (it) | 1979-05-02 |
| IE48224B1 (en) | 1984-10-31 |
| IE790924L (en) | 1979-11-03 |
| FR2424914B2 (es) | 1981-07-24 |
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