ES8207141A1 - Un procedimiento de preparacion de nuevos derivados de la hidroxifenil-tetrahidropiridina . - Google Patents
Un procedimiento de preparacion de nuevos derivados de la hidroxifenil-tetrahidropiridina .Info
- Publication number
- ES8207141A1 ES8207141A1 ES507939A ES507939A ES8207141A1 ES 8207141 A1 ES8207141 A1 ES 8207141A1 ES 507939 A ES507939 A ES 507939A ES 507939 A ES507939 A ES 507939A ES 8207141 A1 ES8207141 A1 ES 8207141A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- carbon atoms
- tetrahydropyridin
- phenols
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE LA HIDROXIFENIL-TETRAHIDROPIRIDINA. CONSISTE EN DESMETILAR UN DERIVADO DE FORMULA GENERAL (I) PARA OBTENER EL DERIVADO (II), EL CUAL O BIEN SE AISLA Y SE SALIFIXA O BIEN SE SOMETE - EN EL CASO DE QUE R'' SEA DIFERENTE DE UN RADICAL ALCOHILO SUSTITUIDO CON UN HIDROXI O UN ARALCOHILO SUSTITUIDO CON UN HIDROXI EN FORMA SALIFICADA- A UNA ACILACION PARA OBTENER EL COMPUESTO (III), EN QUE X'' REPRESENTA UN RADICAL ACILOF YB ES HIDROGENO O UN RADICAL OX''.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8026540A FR2496099A1 (fr) | 1980-12-15 | 1980-12-15 | Nouveaux derives de l'hydroxyphenyl tetrahydropyridine, leurs sels, procede et intermediaires de preparation, application a titre de medicaments et compositions les renfermant |
Publications (2)
Publication Number | Publication Date |
---|---|
ES507939A0 ES507939A0 (es) | 1982-09-01 |
ES8207141A1 true ES8207141A1 (es) | 1982-09-01 |
Family
ID=9249073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES507939A Expired ES8207141A1 (es) | 1980-12-15 | 1981-12-14 | Un procedimiento de preparacion de nuevos derivados de la hidroxifenil-tetrahidropiridina . |
Country Status (13)
Country | Link |
---|---|
US (1) | US4382942A (es) |
JP (1) | JPS57123164A (es) |
AT (1) | AT376662B (es) |
BE (1) | BE891469A (es) |
CA (1) | CA1175437A (es) |
CH (1) | CH651022A5 (es) |
DE (1) | DE3149703A1 (es) |
ES (1) | ES8207141A1 (es) |
FR (1) | FR2496099A1 (es) |
GB (1) | GB2092132B (es) |
IT (1) | IT1172150B (es) |
NL (1) | NL8105623A (es) |
SE (1) | SE450252B (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0192522B1 (fr) * | 1985-02-01 | 1988-08-31 | LABORATOIRE L. LAFON Société anonyme dite: | 1-ethyl - 3-hydroxy-3-phénylpipéridine, procédé de préparation et utilisation en thérapeutique |
FR2576898B1 (fr) * | 1985-02-01 | 1988-01-08 | Lafon Labor | Derives de 3-phenyl-tetrahydropyridine, procede de preparation et utilisation en therapeutique |
EP0398413A1 (en) * | 1989-05-16 | 1990-11-22 | Duphar International Research B.V | "3,4-dehydropiperidine derivatives having psychotropic activity |
US5296497A (en) * | 1989-05-16 | 1994-03-22 | Duphar International Research B.V. | 3,4-dehydropiperidine derivatives having psychotropic activity |
FR2721513B1 (fr) * | 1994-06-23 | 1996-09-06 | Lafon Labor | Utilisation de dérivés de 1,2,5,6-tétrahydropyridine pour la fabrication de médicaments à effet sédatif. |
FR2721514B1 (fr) * | 1994-06-23 | 1996-09-06 | Lafon Labor | Compositions thérapeutiques comprenant des 3-phényl-3-hydroxypipéridines. |
DE102004036349A1 (de) * | 2004-07-27 | 2006-03-23 | Grünenthal GmbH | Substituierte 3-Phenylpiperidin-Derivate |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2498431A (en) * | 1945-06-13 | 1950-02-21 | Hoffmann La Roche | 2-and 4-homocyclyl substituted piperidines |
US3523950A (en) * | 1967-12-13 | 1970-08-11 | Robins Co Inc A H | Certain 4 - phenyl - 1,2,3,6 - tetrahydropyridyl-n-lower alkylene-ureas and derivatives |
FR2310762A1 (fr) * | 1975-05-16 | 1976-12-10 | Roussel Uclaf | Nouveaux derives n-substitues de la phenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments |
FR2310761A1 (fr) * | 1975-05-16 | 1976-12-10 | Roussel Uclaf | Nouveaux derives de la phenyl-piperidine et leurs sels, procede de preparation et application a titre de medicaments |
US4302462A (en) * | 1979-12-20 | 1981-11-24 | Sterling Drug Inc. | 4(or 3)-(3,4-Dihydroxyphenyl)pyridines, their cardiotonic use and cardiotonic use of their methyl ethers |
-
1980
- 1980-12-15 FR FR8026540A patent/FR2496099A1/fr active Granted
-
1981
- 1981-11-10 SE SE8106656A patent/SE450252B/sv not_active IP Right Cessation
- 1981-12-09 US US06/328,930 patent/US4382942A/en not_active Expired - Fee Related
- 1981-12-14 ES ES507939A patent/ES8207141A1/es not_active Expired
- 1981-12-14 CA CA000392246A patent/CA1175437A/fr not_active Expired
- 1981-12-14 GB GB8137631A patent/GB2092132B/en not_active Expired
- 1981-12-14 BE BE0/206827A patent/BE891469A/fr not_active IP Right Cessation
- 1981-12-14 CH CH7968/81A patent/CH651022A5/fr not_active IP Right Cessation
- 1981-12-14 IT IT49903/81A patent/IT1172150B/it active
- 1981-12-14 NL NL8105623A patent/NL8105623A/nl not_active Application Discontinuation
- 1981-12-15 JP JP56201039A patent/JPS57123164A/ja active Pending
- 1981-12-15 DE DE19813149703 patent/DE3149703A1/de not_active Withdrawn
- 1981-12-15 AT AT0536681A patent/AT376662B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IT1172150B (it) | 1987-06-18 |
GB2092132A (en) | 1982-08-11 |
SE450252B (sv) | 1987-06-15 |
SE8106656L (sv) | 1982-06-16 |
JPS57123164A (en) | 1982-07-31 |
AT376662B (de) | 1984-12-27 |
ES507939A0 (es) | 1982-09-01 |
BE891469A (fr) | 1982-06-14 |
GB2092132B (en) | 1985-02-13 |
DE3149703A1 (de) | 1982-06-24 |
IT8149903A0 (it) | 1981-12-14 |
FR2496099B1 (es) | 1983-07-29 |
ATA536681A (de) | 1984-05-15 |
CA1175437A (fr) | 1984-10-02 |
US4382942A (en) | 1983-05-10 |
CH651022A5 (fr) | 1985-08-30 |
FR2496099A1 (fr) | 1982-06-18 |
NL8105623A (nl) | 1982-07-01 |
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