ES487175A1 - Un procedimiento de preparacion de derivados de piperi- dil-indol - Google Patents

Un procedimiento de preparacion de derivados de piperi- dil-indol

Info

Publication number
ES487175A1
ES487175A1 ES487175A ES487175A ES487175A1 ES 487175 A1 ES487175 A1 ES 487175A1 ES 487175 A ES487175 A ES 487175A ES 487175 A ES487175 A ES 487175A ES 487175 A1 ES487175 A1 ES 487175A1
Authority
ES
Spain
Prior art keywords
formula
preparation
indole
nitro
toxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487175A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES487175A1 publication Critical patent/ES487175A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)

Abstract

Un procedimiento de preparación de derivados de piperidil-indol, así como de sus sales de adición con ácidos minerales u orgánicos, derivados que responden a la formula I: **(fórmula)**en la que X representa un átomo de hidrógeno, flúor, cloro, bromo, un radical alcoxi que contiene de 1 a 3 átomos de carbono, o un radical nitro, y R representa un átomo de hidrógeno o un radical alcohilo que contiene de 1 a 3 átomo de carbono, o un radical nitro, y R representa un átomo de hidrógeno o un radical alcohilo que contiene de 1 a 3 átomos de carbono.
ES487175A 1978-12-22 1979-12-21 Un procedimiento de preparacion de derivados de piperi- dil-indol Expired ES487175A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7836167A FR2444678A2 (fr) 1978-12-22 1978-12-22 Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels

Publications (1)

Publication Number Publication Date
ES487175A1 true ES487175A1 (es) 1980-09-16

Family

ID=9216467

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487175A Expired ES487175A1 (es) 1978-12-22 1979-12-21 Un procedimiento de preparacion de derivados de piperi- dil-indol

Country Status (17)

Country Link
US (1) US4232031A (es)
JP (1) JPS5587786A (es)
AT (1) AT375361B (es)
AU (1) AU529439B2 (es)
BE (1) BE880818A (es)
CA (1) CA1128946A (es)
CH (1) CH642963A5 (es)
DE (1) DE2951912A1 (es)
ES (1) ES487175A1 (es)
FR (1) FR2444678A2 (es)
GB (1) GB2039277B (es)
HU (1) HU181947B (es)
IE (1) IE49343B1 (es)
IT (1) IT1164031B (es)
NL (1) NL7909136A (es)
SE (1) SE440651B (es)
ZA (1) ZA796386B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2420536A1 (fr) * 1978-03-22 1979-10-19 Roussel Uclaf Nouveaux derives de 1,3-dihydro 3-/1-/2-(2,3-dihydro 1,4-benzodioxin-2-yl)2-hydroxyethyl/piperidin-4-yl/2h-indol-2-one, procede pour leur preparation et application comme medicaments
FR2460947A1 (fr) * 1979-07-13 1981-01-30 Roussel Uclaf Nouveau derives n-substitues du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
SE8004129L (sv) * 1979-07-13 1981-01-14 Roussel Uclaf Nya tetrahydropyridin-4-yl-indolderivat samt salter derav, framstellning och anvendning derav sasom lekemedel samt kompositioner innehallande dessa foreningar
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
WO1990007926A1 (en) * 1989-01-20 1990-07-26 Pfizer Inc. 3-(1,2,5,6-tetrahydropyridyl)-pyrrolopyridines
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
WO2004069828A1 (ja) * 2003-02-04 2004-08-19 Mitsubishi Pharma Corporation ピペリジン化合物およびその医薬用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872453A (en) * 1959-02-03 Indole derivatives
FR2193584B1 (es) * 1972-07-28 1975-08-08 Roussel Uclaf
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2258843B1 (es) * 1974-01-30 1977-09-09 Roussel Uclaf
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
JPS5283766A (en) * 1976-01-01 1977-07-12 Roussel Uclaf Piperidyl indole derivative and its salts and medicine comprising same
FR2349331A1 (fr) * 1976-04-30 1977-11-25 Roussel Uclaf Nouveaux derives de 2,3 dihydro a/4-(3-indolyl) 1-piperidinyl/methyl 1,4-benzodioxin-2-methanol, un procede pour leur preparation et leur application comme medicaments
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments

Also Published As

Publication number Publication date
HU181947B (en) 1983-11-28
IE49343B1 (en) 1985-09-18
GB2039277A (en) 1980-08-06
CA1128946A (fr) 1982-08-03
AU529439B2 (en) 1983-06-09
SE7909367L (sv) 1980-06-23
DE2951912A1 (de) 1980-07-10
JPS5587786A (en) 1980-07-02
CH642963A5 (fr) 1984-05-15
FR2444678A2 (fr) 1980-07-18
DE2951912C2 (es) 1989-05-11
NL7909136A (nl) 1980-06-24
IT7951166A0 (it) 1979-12-21
JPS6345387B2 (es) 1988-09-09
US4232031A (en) 1980-11-04
AT375361B (de) 1984-07-25
IE792508L (en) 1980-06-22
IT1164031B (it) 1987-04-08
GB2039277B (en) 1983-03-02
FR2444678B2 (es) 1982-09-17
ZA796386B (en) 1980-10-29
SE440651B (sv) 1985-08-12
BE880818A (fr) 1980-06-23
AU5415279A (en) 1980-06-26
ATA809679A (de) 1983-12-15

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