ES8105981A1 - Procedimiento para la preparacion de derivados de 4-(nafta- leniloxi)piperidina - Google Patents
Procedimiento para la preparacion de derivados de 4-(nafta- leniloxi)piperidinaInfo
- Publication number
- ES8105981A1 ES8105981A1 ES493591A ES493591A ES8105981A1 ES 8105981 A1 ES8105981 A1 ES 8105981A1 ES 493591 A ES493591 A ES 493591A ES 493591 A ES493591 A ES 493591A ES 8105981 A1 ES8105981 A1 ES 8105981A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- alkyl
- naphthalenyloxy
- alkoxy
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE 4-(NAFTALENILOXI) PIPERIDINA DE FORMULA (I), DE SU ISOMERO OPTICO O DE UNA SAL, DONDE "N" ES UN NUMERO ENTERO DE 2 A 5, Z ES UN CARBONILO O HIDROXIMETILENO Y R Y R1 PUEDEN SER HIDROGENO, HALOGENO, ALCOXI O ALQUILO. CONSISTE EN ALQUILIZAR UN COMPUESSTO DE FORMULA (II) CON OTRO DE FORMULA (III) EN UN MEDIO DISOLVENTE, EN PRESENCIA DE UNA BASE, Y OPCIONALMENTE CON UNA CANTIDAD CATALITICA DE YODURO POTASICO. EL TIEMPO DE REACCION ESTA COMPRENDIDO ENTRE 24 Y 96 HORAS, Y LA TEMPERATURA, ENTRE 90 Y 180 GC. CUANDO SE DESEA OBTENER UNA SAL SE HACE REACCIONAR EL COMPUESTO OBTENIDO CON UN ACIDO. DE APLICACION COMO TRANQUILIZANTES NEUROLEPTICOS. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6430579A | 1979-08-06 | 1979-08-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES493591A0 ES493591A0 (es) | 1981-07-01 |
ES8105981A1 true ES8105981A1 (es) | 1981-07-01 |
Family
ID=22055014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES493591A Expired ES8105981A1 (es) | 1979-08-06 | 1980-07-22 | Procedimiento para la preparacion de derivados de 4-(nafta- leniloxi)piperidina |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS5626875A (es) |
AU (1) | AU534398B2 (es) |
BE (1) | BE884581A (es) |
CA (1) | CA1123440A (es) |
CH (1) | CH644364A5 (es) |
DE (1) | DE3028064A1 (es) |
DK (1) | DK150477C (es) |
ES (1) | ES8105981A1 (es) |
FR (1) | FR2463129A1 (es) |
GB (1) | GB2056447B (es) |
IE (1) | IE49998B1 (es) |
IL (1) | IL60593A (es) |
IT (1) | IT1146966B (es) |
NL (1) | NL8004147A (es) |
NO (1) | NO153726C (es) |
NZ (1) | NZ194248A (es) |
SE (1) | SE448728B (es) |
ZA (1) | ZA804112B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2508445A1 (fr) * | 1981-06-29 | 1982-12-31 | Sori Soc Rech Ind | Nouveaux derives de benzoyl-phenyl-piperidine, leur procede de preparation et leur application, notamment en therapeutique |
DE3170628D1 (en) * | 1981-10-15 | 1985-06-27 | Synthelabo | Piperidine derivatives, their preparation and use in medicine |
GB8321157D0 (en) * | 1983-08-05 | 1983-09-07 | Fordonal Sa | Piperidine derivatives |
JP2751346B2 (ja) * | 1989-03-15 | 1998-05-18 | ミノルタ株式会社 | プリンタ |
US8188090B2 (en) * | 2008-11-17 | 2012-05-29 | Hoffman-La Roche Inc. | Naphthylacetic acids |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB895309A (en) * | 1959-11-18 | 1962-05-02 | Res Lab Dr C Janssen Nv | Pyrrolidine and piperidine derivatives |
BE637978A (es) * | 1963-02-15 | |||
US3743645A (en) * | 1970-10-19 | 1973-07-03 | Robins Co Inc A H | 1-substituted-4-phenoxypiperidines |
ZA717147B (en) * | 1970-11-27 | 1972-07-26 | Richardson Merrell Inc | 4-(4-(alpha-hydroxybenzyl)piperidino)-4'-fluorobutyrophenone derivatives |
US3806526A (en) * | 1972-01-28 | 1974-04-23 | Richardson Merrell Inc | 1-aroylalkyl-4-diphenylmethyl piperidines |
SE7409245L (es) * | 1973-07-19 | 1975-01-20 | Robins Co Inc A H | |
DE2718405A1 (de) * | 1977-04-26 | 1978-11-02 | Boehringer Sohn Ingelheim | Neue n- eckige klammer auf 1-(3-benzoylpropyl)-4-piperidyl eckige klammer zu -sulfonsaeureamide und verfahren zu deren herstellung |
US4134982A (en) * | 1977-09-26 | 1979-01-16 | Warner-Lambert Company | Antipsychotic 1-[4,4-Bis(4-fluorophenyl) butyl]-4-phenoxy-1,2,3,6-tetrahydropyridines |
-
1980
- 1980-07-01 IE IE1382/80A patent/IE49998B1/en not_active IP Right Cessation
- 1980-07-03 CA CA355,369A patent/CA1123440A/en not_active Expired
- 1980-07-04 NZ NZ194248A patent/NZ194248A/en unknown
- 1980-07-08 ZA ZA00804112A patent/ZA804112B/xx unknown
- 1980-07-14 AU AU60394/80A patent/AU534398B2/en not_active Ceased
- 1980-07-15 IL IL60593A patent/IL60593A/xx unknown
- 1980-07-18 NL NL8004147A patent/NL8004147A/nl not_active Application Discontinuation
- 1980-07-22 ES ES493591A patent/ES8105981A1/es not_active Expired
- 1980-07-24 DE DE19803028064 patent/DE3028064A1/de active Granted
- 1980-07-31 IT IT49394/80A patent/IT1146966B/it active
- 1980-07-31 BE BE0/201611A patent/BE884581A/fr not_active IP Right Cessation
- 1980-07-31 SE SE8005493A patent/SE448728B/sv not_active IP Right Cessation
- 1980-08-01 GB GB8025192A patent/GB2056447B/en not_active Expired
- 1980-08-01 JP JP10521180A patent/JPS5626875A/ja active Granted
- 1980-08-04 CH CH590380A patent/CH644364A5/de not_active IP Right Cessation
- 1980-08-05 FR FR8017290A patent/FR2463129A1/fr active Granted
- 1980-08-05 NO NO802346A patent/NO153726C/no unknown
- 1980-08-05 DK DK337280A patent/DK150477C/da active
Also Published As
Publication number | Publication date |
---|---|
GB2056447B (en) | 1983-07-06 |
SE8005493L (sv) | 1981-02-07 |
DE3028064A1 (de) | 1981-02-26 |
DE3028064C2 (es) | 1989-11-09 |
FR2463129B1 (es) | 1983-04-22 |
ES493591A0 (es) | 1981-07-01 |
GB2056447A (en) | 1981-03-18 |
JPS5626875A (en) | 1981-03-16 |
IT8049394A0 (it) | 1980-07-31 |
IE801382L (en) | 1981-02-06 |
DK150477B (da) | 1987-03-09 |
CA1123440A (en) | 1982-05-11 |
NO802346L (no) | 1981-02-09 |
NZ194248A (en) | 1984-07-06 |
BE884581A (fr) | 1980-11-17 |
NL8004147A (nl) | 1981-02-10 |
AU534398B2 (en) | 1984-01-26 |
IL60593A (en) | 1984-03-30 |
IE49998B1 (en) | 1986-01-22 |
CH644364A5 (de) | 1984-07-31 |
FR2463129A1 (fr) | 1981-02-20 |
JPS6341390B2 (es) | 1988-08-17 |
NO153726B (no) | 1986-02-03 |
DK337280A (da) | 1981-02-07 |
IL60593A0 (en) | 1980-09-16 |
AU6039480A (en) | 1981-02-12 |
NO153726C (no) | 1986-05-14 |
SE448728B (sv) | 1987-03-16 |
DK150477C (da) | 1987-10-12 |
ZA804112B (en) | 1981-07-29 |
IT1146966B (it) | 1986-11-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970519 |