ES468675A1 - Procedimiento de fabricacion de tiobencilpirimidinas y sus compuestos medicamentosos. - Google Patents

Procedimiento de fabricacion de tiobencilpirimidinas y sus compuestos medicamentosos.

Info

Publication number
ES468675A1
ES468675A1 ES468675A ES468675A ES468675A1 ES 468675 A1 ES468675 A1 ES 468675A1 ES 468675 A ES468675 A ES 468675A ES 468675 A ES468675 A ES 468675A ES 468675 A1 ES468675 A1 ES 468675A1
Authority
ES
Spain
Prior art keywords
diamino
compounds
benzylpyrimidenes
methylthio
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES468675A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heumann Ludwig and Co GmbH
Original Assignee
Heumann Ludwig and Co GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Ludwig and Co GmbH filed Critical Heumann Ludwig and Co GmbH
Publication of ES468675A1 publication Critical patent/ES468675A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento de fabricación de tiobencilpirimidinas y sus compuestos medicamentosos. Con la siguiente forma general: **(Fórmula)** en la que R representa un átomo de hidrógeno, un grupo alquilo, un grupo alcoxi bajo o un átomo halógeno, y R¿ representa un grupo alquilo, así como sus sales ácidas de adición tolerables farmacológicamente.
ES468675A 1977-05-09 1978-04-10 Procedimiento de fabricacion de tiobencilpirimidinas y sus compuestos medicamentosos. Expired ES468675A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2720771A DE2720771C3 (de) 1977-05-09 1977-05-09 2,4-Diamino-5-(33-dimethoxy-4thioalkyl-benzyD-pyrimidine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ES468675A1 true ES468675A1 (es) 1978-12-01

Family

ID=6008425

Family Applications (1)

Application Number Title Priority Date Filing Date
ES468675A Expired ES468675A1 (es) 1977-05-09 1978-04-10 Procedimiento de fabricacion de tiobencilpirimidinas y sus compuestos medicamentosos.

Country Status (20)

Country Link
US (1) US4180578A (es)
JP (1) JPS53137976A (es)
AR (1) AR219739A1 (es)
AT (1) AT360029B (es)
AU (1) AU516233B2 (es)
BE (1) BE865834A (es)
CA (1) CA1071627A (es)
CH (1) CH639959A5 (es)
DE (1) DE2720771C3 (es)
ES (1) ES468675A1 (es)
FR (1) FR2390435A1 (es)
GB (1) GB1572077A (es)
GR (1) GR66495B (es)
HU (1) HU178239B (es)
IL (1) IL54336A (es)
IT (1) IT1108036B (es)
MX (1) MX4991E (es)
NL (1) NL7803559A (es)
PT (1) PT67869B (es)
ZA (1) ZA781693B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2910510A1 (de) * 1979-03-16 1980-09-25 Heumann Ludwig & Co Gmbh 2,4-diamino-5-benzylpyrimidine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3603577A1 (de) * 1986-02-06 1987-08-13 Joachim K Prof Dr Seydel Neue substituierte 2,4-diamino-5-benzylpyrimidine, deren herstellung und deren verwendung als arzneimittel mit antibakterieller wirksamkeit
RU95113597A (ru) * 1992-12-02 1997-06-10 ФМК Корпорейшн (US) Инсектицидная композиция, способы борьбы с насекомыми
US5622954A (en) * 1994-05-11 1997-04-22 Fmc Corporation 5[W(substituted aryl)alkenylene and alkynylene]-2,4-diaminopyrimidines as pesticides

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1720012U (de) 1952-06-20 1956-04-05 Petermann Werke Vorrichtung zum abtrennen der blattkronen von im erdboden stehenden wurzelfruechten, insbesondere zuckerrueben.
DE1303727B (de) 1959-09-03 1976-02-05 Ausscheidung aus: 14 45 176 The Wellcome Foundation Ltd., London Alpha-Arylidensubstituierte Propioni-Irile
BE710100A (es) 1967-02-02 1968-07-30
US3855265A (en) * 1969-03-06 1974-12-17 Burroughs Wellcome Co 5-benzyl pyrimidines intermediates therefore, and method
US3852276A (en) * 1969-03-06 1974-12-03 Burroughs Wellcome Co 5-benzyl pyrimidines intermediate therefore, and method
US3850927A (en) * 1969-03-06 1974-11-26 Burroughs Wellcome Co 5-benzyl pyrimidines intermediates therefore,and method
DE2065367C2 (de) 1969-03-06 1985-04-04 The Wellcome Foundation Ltd., London Verfahren zur Herstellung von 2,4- Diamino-5-benzylpyrimidinen
US3692787A (en) * 1970-02-16 1972-09-19 Burroughs Wellcome Co Substituted 2,4-diamino-5-benzyl pyrimidines
GB1401612A (en) * 1971-04-16 1975-07-16 Wellcome Found 2,4-diamino-5-benzylpyrimidines and preparations thereof
US4076810A (en) * 1973-11-08 1978-02-28 Hoffmann-La Roche Inc. Benzylpyrimidine antibacterial composition
DE2546667C3 (de) 1975-10-17 1978-10-12 Ludwig Heumann & Co Gmbh, 8500 Nuernberg 2,4-DiamüH»-5-(3-methoxy-4-hydroxy-5-halogenbenzyl)-pyrimidine, und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
ATA251578A (de) 1980-05-15
FR2390435B1 (es) 1980-08-29
GR66495B (es) 1981-03-24
IT1108036B (it) 1985-12-02
MX4991E (es) 1983-01-31
BE865834A (fr) 1978-07-31
NL7803559A (nl) 1978-11-13
DE2720771A1 (de) 1978-11-16
AR219739A1 (es) 1980-09-15
CH639959A5 (de) 1983-12-15
AU516233B2 (en) 1981-05-21
JPS53137976A (en) 1978-12-01
HU178239B (en) 1982-04-28
IL54336A0 (en) 1978-06-15
FR2390435A1 (fr) 1978-12-08
AU3495578A (en) 1979-10-18
PT67869B (de) 1979-11-14
CA1071627A (en) 1980-02-12
GB1572077A (en) 1980-07-23
IL54336A (en) 1981-07-31
AT360029B (de) 1980-12-10
PT67869A (de) 1978-05-01
ZA781693B (en) 1979-09-26
US4180578A (en) 1979-12-25
DE2720771B2 (de) 1979-04-05
IT7867740A0 (it) 1978-04-04
DE2720771C3 (de) 1979-11-29

Similar Documents

Publication Publication Date Title
PH15864A (en) 2-(2-alkoxy-methyl)-2-hydroxy-6-7 benzomorphans and salts thereof
ES473817A1 (es) Procedimiento para preparar derivados de piperazina.
ES486824A1 (es) Procedimiento para la preparacion de nuevos derivados de 4- (naftilmetil) piperidinas
ES473925A1 (es) Un procedimiento para la preparacion de un oligopeptido
ES8705425A1 (es) Un compuesto.
ES475173A1 (es) Procedimiento para la fabricacion de quinazolinas.
ES8800122A1 (es) Un procedimiento para la preparacion de derivados de indeno y naftaleno.
ES477785A1 (es) Procedimiento para la preparacion de nuevas 2-fenilimino- imidazolidinas sustituidas.
ES468675A1 (es) Procedimiento de fabricacion de tiobencilpirimidinas y sus compuestos medicamentosos.
ES8702433A1 (es) Un procedimiento para la preparacion de un compuesto heterociclico sustituido con peptidos.
ES8400404A1 (es) Un procedimiento para la preparacion de derivados de fenilpiperidina sustituidos.
ES479833A1 (es) Un procedimiento para preparar mercatoacilaminoacidos susti-tuidos con halogeno.
SE8304071L (sv) Nya piperazinderivat
ES476385A1 (es) Un procedimiento para preparar derivados de transpirindina
ES2003086A6 (es) Procedimiento de obtencion de tienoquinolicinsulfonamidas
PH18226A (en) 1-phenylindazol-3-one-compounds,a method of preparing them and pharmaceutical compositions containing these compounds
ES8506641A1 (es) Procedimiento para preparar 1-acetonil-2-(fenilimino)-imidazolidinas
ES8105981A1 (es) Procedimiento para la preparacion de derivados de 4-(nafta- leniloxi)piperidina
ES8205219A1 (es) Un metodo para producir un compuesto de hidrouracilo
IL67360A0 (en) Alpha-azolylglycols and their use as fungicides
ES8705426A1 (es) Un procedimiento para la preparacion de un derivado de piperazina.
ES477709A1 (es) Procedimiento de preparacion de nuevos compuestos cis- y trans-1,5-benzotiacepinicos.
ES8400420A1 (es) "procedimiento para la fabricacion de derivados n- susbtituidos de la tetrahidroisftalimida".
ES469450A1 (es) Ÿun procedimiento para la preparacion de bencilpirimidinasŸ
ES472408A1 (es) Procedimiento para la preparacion de nuevos 2'- hidroxi-2-(5-isoxazolimetil)-6,7-benzomorfanos.