ES8507090A1 - Procedimiento para la obtencion de nuevas 1, 5-benzotiacepinas - Google Patents
Procedimiento para la obtencion de nuevas 1, 5-benzotiacepinasInfo
- Publication number
- ES8507090A1 ES8507090A1 ES534539A ES534539A ES8507090A1 ES 8507090 A1 ES8507090 A1 ES 8507090A1 ES 534539 A ES534539 A ES 534539A ES 534539 A ES534539 A ES 534539A ES 8507090 A1 ES8507090 A1 ES 8507090A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- benzothiazepines
- groups
- alkoxy
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE NUEVAS 1,5-BENZOTIACEPINAS.COMPRENDE: HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN AGENTE ACILANTE O CARBAMOILANTE, EN PRESENCIA DE UNA BASE ORGANICA, EN UN PERIODO DE TIEMPO DE 5 A 30H Y A UNA TEMPERATURA ENTRE LA DE AMBIENTE Y 60JC PARA OBTENER LAS BASES LIBRES DE FORMULA (I), EN DONDE R1 ES ALQUILO DE C 1 A 9, ALCOXILO DE C 1 A 4 U OTROS, R2 DE C 1 A 4 U OTROS, Y R3 Y R4 ALQUILO DE C 1 A 4.SE UTILIZA PARA EL TRATAMIENTO DE ENFERMEDADES CARDIACAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8322185A IT1206505B (it) | 1983-07-22 | 1983-07-22 | Nuovi derivati benzotiazepinonici, metodo per la loro preparazione e composizioni farmaceutiche che licontengono. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES534539A0 ES534539A0 (es) | 1985-09-16 |
ES8507090A1 true ES8507090A1 (es) | 1985-09-16 |
Family
ID=11192749
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES534539A Expired ES8507090A1 (es) | 1983-07-22 | 1984-07-21 | Procedimiento para la obtencion de nuevas 1, 5-benzotiacepinas |
Country Status (24)
Country | Link |
---|---|
US (1) | US4547495A (es) |
JP (1) | JPS6042374A (es) |
KR (1) | KR910005708B1 (es) |
AT (1) | AT392070B (es) |
AU (1) | AU560729B2 (es) |
BE (1) | BE900192A (es) |
CA (1) | CA1223583A (es) |
CH (1) | CH661508A5 (es) |
DE (1) | DE3426821A1 (es) |
DK (1) | DK165117C (es) |
ES (1) | ES8507090A1 (es) |
FI (1) | FI80881C (es) |
FR (1) | FR2567882B1 (es) |
GB (1) | GB2143532B (es) |
GR (1) | GR79983B (es) |
IE (1) | IE57663B1 (es) |
IL (1) | IL72368A (es) |
IT (1) | IT1206505B (es) |
LU (1) | LU85473A1 (es) |
NL (1) | NL8402255A (es) |
NZ (1) | NZ208761A (es) |
PT (1) | PT78955B (es) |
SE (1) | SE461219B (es) |
ZA (1) | ZA845095B (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4925837A (en) * | 1984-09-14 | 1990-05-15 | Synthelabo | Pharmaceutical compositions |
GB2167063A (en) * | 1984-11-17 | 1986-05-21 | Tanabe Seiyaku Co | 6 or 9-chloro-1, 5-benzothiazepine derivatives |
USRE33072E (en) * | 1985-06-20 | 1989-09-26 | E. R. Squibb & Sons, Inc. | Benzothiazepine derivatives |
US4584131A (en) * | 1985-06-20 | 1986-04-22 | E. R. Squibb & Sons, Inc. | Benzothiazepine derivatives |
US4652561A (en) * | 1986-02-26 | 1987-03-24 | Hoffmann-La Roche Inc. | Naphtho[1,2-b]-1,4-thiazepinones |
IL81954A0 (en) * | 1986-03-24 | 1987-10-20 | Hoffmann La Roche | Naphthothiazocinones,their manufacture and pharmaceutical compositions containing them |
JPS63275572A (ja) * | 1987-05-01 | 1988-11-14 | Tanabe Seiyaku Co Ltd | 1,5−ベンゾチアゼピン誘導体 |
JP2703564B2 (ja) * | 1987-07-31 | 1998-01-26 | 田辺製薬株式会社 | 1,5−ベンゾチアゼピン誘導体 |
US4808580A (en) * | 1987-12-17 | 1989-02-28 | Hoffmann-La Roche Inc. | Naphtho[1,2-b][1,4]thiazepin-4(5H)-ones and use thereof in treatment of ischemia and blood pressure lowering |
US4912102A (en) * | 1988-02-01 | 1990-03-27 | Hoffmann-La Roche Inc. | Analogs of naphtho[1,2-β] [1,4] thiazepin-4(5H)-one |
JP2674232B2 (ja) * | 1989-08-31 | 1997-11-12 | 田辺製薬株式会社 | 1,5―ベンゾチアゼピン誘導体 |
US5001236A (en) * | 1989-11-22 | 1991-03-19 | Marion Laboratories, Inc. | Benzothiazepines |
IT1240686B (it) * | 1990-04-27 | 1993-12-17 | Luso Farmaco Inst | Derivati 1,5-benzotiazepinonici, loro preparazione e uso farmaceutico |
JP3151163B2 (ja) * | 1997-01-24 | 2001-04-03 | ソニーケミカル株式会社 | 記録用シート及びその記録用シートを使った記録方法 |
KR100397799B1 (ko) * | 2001-07-11 | 2003-09-13 | 송기만 | 조명갓의 표면처리 방법 |
KR100436262B1 (ko) * | 2002-01-04 | 2004-06-16 | 삼성전자주식회사 | 전자레인지용 램프의 제조방법 |
JP2011511007A (ja) * | 2008-02-01 | 2011-04-07 | ザ スクリプス リサーチ インスティチュート | タンパク質ホメオスタシスの機能不全を特徴とする状態を治療するための方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5899471A (ja) * | 1981-12-07 | 1983-06-13 | Tanabe Seiyaku Co Ltd | ベンゾチアゼピン誘導体の新規製造法 |
-
1983
- 1983-07-22 IT IT8322185A patent/IT1206505B/it active
-
1984
- 1984-07-03 NZ NZ208761A patent/NZ208761A/en unknown
- 1984-07-03 ZA ZA845095A patent/ZA845095B/xx unknown
- 1984-07-09 US US06/628,730 patent/US4547495A/en not_active Expired - Fee Related
- 1984-07-10 IL IL72368A patent/IL72368A/xx unknown
- 1984-07-17 NL NL8402255A patent/NL8402255A/nl not_active Application Discontinuation
- 1984-07-18 AT AT0232384A patent/AT392070B/de not_active IP Right Cessation
- 1984-07-18 KR KR1019840004202A patent/KR910005708B1/ko not_active IP Right Cessation
- 1984-07-18 FR FR8411380A patent/FR2567882B1/fr not_active Expired
- 1984-07-20 DK DK356484A patent/DK165117C/da not_active IP Right Cessation
- 1984-07-20 AU AU30923/84A patent/AU560729B2/en not_active Ceased
- 1984-07-20 FI FI842927A patent/FI80881C/fi not_active IP Right Cessation
- 1984-07-20 BE BE2/60463A patent/BE900192A/fr not_active IP Right Cessation
- 1984-07-20 PT PT78955A patent/PT78955B/pt not_active IP Right Cessation
- 1984-07-20 IE IE1881/84A patent/IE57663B1/en not_active IP Right Cessation
- 1984-07-20 DE DE19843426821 patent/DE3426821A1/de active Granted
- 1984-07-20 SE SE8403801A patent/SE461219B/sv not_active IP Right Cessation
- 1984-07-20 CA CA000459353A patent/CA1223583A/en not_active Expired
- 1984-07-20 JP JP59149766A patent/JPS6042374A/ja active Pending
- 1984-07-20 GR GR75393A patent/GR79983B/el unknown
- 1984-07-20 CH CH3557/84A patent/CH661508A5/de not_active IP Right Cessation
- 1984-07-20 LU LU85473A patent/LU85473A1/fr unknown
- 1984-07-21 ES ES534539A patent/ES8507090A1/es not_active Expired
- 1984-07-23 GB GB08418744A patent/GB2143532B/en not_active Expired
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970612 |