YU45900B - Postupak za dobijanje n-oksid estara piridilkarbonske kiseline - Google Patents
Postupak za dobijanje n-oksid estara piridilkarbonske kiselineInfo
- Publication number
- YU45900B YU45900B YU74384A YU74384A YU45900B YU 45900 B YU45900 B YU 45900B YU 74384 A YU74384 A YU 74384A YU 74384 A YU74384 A YU 74384A YU 45900 B YU45900 B YU 45900B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- acid
- preparation
- cyclohexyl
- pyridyl
- carbonic acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 title 1
- -1 N-oxide ester Chemical class 0.000 abstract 4
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- KFSLWBXXFJQRDL-UHFFFAOYSA-N Peracetic acid Chemical compound CC(=O)OO KFSLWBXXFJQRDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 2
- NHQDETIJWKXCTC-UHFFFAOYSA-N 3-chloroperbenzoic acid Chemical compound OOC(=O)C1=CC=CC(Cl)=C1 NHQDETIJWKXCTC-UHFFFAOYSA-N 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 229960000583 acetic acid Drugs 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000012362 glacial acetic acid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000004965 peroxy acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833315877 DE3315877A1 (de) | 1983-05-02 | 1983-05-02 | N-oxide von pyridyl-carbonsaeureestern, ein verfahren zu ihrer herstellung und pharmazeutische mittel, die diese verbindungen enthalten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU74384A YU74384A (en) | 1986-10-31 |
| YU45900B true YU45900B (sh) | 1992-09-07 |
Family
ID=6197884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU74384A YU45900B (sh) | 1983-05-02 | 1984-04-26 | Postupak za dobijanje n-oksid estara piridilkarbonske kiseline |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4758581A (xx) |
| JP (1) | JPS59206357A (xx) |
| KR (1) | KR860001907B1 (xx) |
| AU (1) | AU564780B2 (xx) |
| BE (1) | BE899558A (xx) |
| CA (1) | CA1247092A (xx) |
| CH (1) | CH660005A5 (xx) |
| CS (1) | CS241082B2 (xx) |
| DE (1) | DE3315877A1 (xx) |
| DK (1) | DK159105C (xx) |
| ES (1) | ES8503660A1 (xx) |
| FI (1) | FI80444C (xx) |
| FR (1) | FR2545486B1 (xx) |
| GB (1) | GB2139621B (xx) |
| GR (1) | GR79862B (xx) |
| HU (1) | HU191681B (xx) |
| IE (1) | IE57393B1 (xx) |
| IL (1) | IL71734A (xx) |
| IT (1) | IT1206144B (xx) |
| LU (1) | LU85344A1 (xx) |
| NL (1) | NL8401357A (xx) |
| SE (1) | SE454986B (xx) |
| YU (1) | YU45900B (xx) |
| ZA (1) | ZA843278B (xx) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
| US6676967B1 (en) | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
| US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
| US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
| US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1256M (fr) * | 1961-06-26 | 1962-04-16 | M I P Soc Amilloise De Prod Ch | Médicament hypocholésterolémiant a base de n-oxyde de l'acide nicotinique. |
| GB1213162A (en) * | 1966-11-16 | 1970-11-18 | Astra Ab | Serum lipid lowering pyridine derivatives and their preparation |
| AT291853B (de) * | 1967-03-22 | 1971-08-10 | Buero Patent Ag | Automatische, gleislose Förderanlage |
| DE3009099A1 (de) * | 1980-03-10 | 1981-09-17 | Merz + Co GmbH & Co, 6000 Frankfurt | Neue phenylester der nikotinsaeure und verfahren zu ihrer herstellung |
| US4321268A (en) * | 1979-02-08 | 1982-03-23 | Merz & Co. | Certain substituted phenyl esters of nicotinic acid, compositions and methods of using same |
| GB2193359B (en) * | 1986-07-31 | 1990-07-11 | Multitone Electronics Plc | Area communications systems |
| US4797656A (en) * | 1987-01-28 | 1989-01-10 | Keppler Charles N | Appliance paging system |
| US5012749A (en) * | 1988-12-27 | 1991-05-07 | The Allen Group Inc. | Radio controlled material handling apparatus |
| US4962377A (en) * | 1989-02-09 | 1990-10-09 | Motorola, Inc. | Paging by text matching |
-
1983
- 1983-05-02 DE DE19833315877 patent/DE3315877A1/de active Granted
-
1984
- 1984-04-26 CH CH2092/84A patent/CH660005A5/de not_active IP Right Cessation
- 1984-04-26 SE SE8402297A patent/SE454986B/sv not_active IP Right Cessation
- 1984-04-26 YU YU74384A patent/YU45900B/sh unknown
- 1984-04-27 NL NL8401357A patent/NL8401357A/nl not_active Application Discontinuation
- 1984-04-28 HU HU841684A patent/HU191681B/hu not_active IP Right Cessation
- 1984-04-30 GR GR74551A patent/GR79862B/el unknown
- 1984-04-30 ES ES532079A patent/ES8503660A1/es not_active Expired
- 1984-04-30 KR KR1019840002323A patent/KR860001907B1/ko not_active IP Right Cessation
- 1984-05-01 DK DK216484A patent/DK159105C/da not_active IP Right Cessation
- 1984-05-01 GB GB08411081A patent/GB2139621B/en not_active Expired
- 1984-05-01 IE IE1074/84A patent/IE57393B1/en not_active IP Right Cessation
- 1984-05-01 CA CA000453248A patent/CA1247092A/en not_active Expired
- 1984-05-02 IT IT8420763A patent/IT1206144B/it active
- 1984-05-02 LU LU85344A patent/LU85344A1/fr unknown
- 1984-05-02 FI FI841736A patent/FI80444C/fi not_active IP Right Cessation
- 1984-05-02 JP JP59087963A patent/JPS59206357A/ja active Granted
- 1984-05-02 FR FR8406845A patent/FR2545486B1/fr not_active Expired
- 1984-05-02 ZA ZA843278A patent/ZA843278B/xx unknown
- 1984-05-02 BE BE0/212858A patent/BE899558A/fr not_active IP Right Cessation
- 1984-05-02 IL IL71734A patent/IL71734A/xx unknown
- 1984-05-02 AU AU27604/84A patent/AU564780B2/en not_active Ceased
- 1984-05-02 CS CS843252A patent/CS241082B2/cs unknown
-
1987
- 1987-09-29 US US07/102,025 patent/US4758581A/en not_active Expired - Fee Related
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