DK216484A - N-oxider af pyridylcarboxylsyreestere og fremgangsmaade til fremstilling heraf - Google Patents

N-oxider af pyridylcarboxylsyreestere og fremgangsmaade til fremstilling heraf Download PDF

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Publication number
DK216484A
DK216484A DK216484A DK216484A DK216484A DK 216484 A DK216484 A DK 216484A DK 216484 A DK216484 A DK 216484A DK 216484 A DK216484 A DK 216484A DK 216484 A DK216484 A DK 216484A
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DK
Denmark
Prior art keywords
pyridyl
oxides
procedures
preparing
acid esters
Prior art date
Application number
DK216484A
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English (en)
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DK159105C (da
DK216484D0 (da
DK159105B (da
Inventor
Arthur Scherm
Klaus Hummel
Dezsoe Peteri
Wolfgang Schatton
Original Assignee
Merz & Co Gmbh & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Merz & Co Gmbh & Co filed Critical Merz & Co Gmbh & Co
Publication of DK216484D0 publication Critical patent/DK216484D0/da
Publication of DK216484A publication Critical patent/DK216484A/da
Publication of DK159105B publication Critical patent/DK159105B/da
Application granted granted Critical
Publication of DK159105C publication Critical patent/DK159105C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK216484A 1983-05-02 1984-05-01 N-oxider af nikotinsyreestere samt farmaceutiske praeparater indeholdende saadanne DK159105C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833315877 DE3315877A1 (de) 1983-05-02 1983-05-02 N-oxide von pyridyl-carbonsaeureestern, ein verfahren zu ihrer herstellung und pharmazeutische mittel, die diese verbindungen enthalten
DE3315877 1983-05-02

Publications (4)

Publication Number Publication Date
DK216484D0 DK216484D0 (da) 1984-05-01
DK216484A true DK216484A (da) 1984-11-03
DK159105B DK159105B (da) 1990-09-03
DK159105C DK159105C (da) 1991-02-11

Family

ID=6197884

Family Applications (1)

Application Number Title Priority Date Filing Date
DK216484A DK159105C (da) 1983-05-02 1984-05-01 N-oxider af nikotinsyreestere samt farmaceutiske praeparater indeholdende saadanne

Country Status (24)

Country Link
US (1) US4758581A (da)
JP (1) JPS59206357A (da)
KR (1) KR860001907B1 (da)
AU (1) AU564780B2 (da)
BE (1) BE899558A (da)
CA (1) CA1247092A (da)
CH (1) CH660005A5 (da)
CS (1) CS241082B2 (da)
DE (1) DE3315877A1 (da)
DK (1) DK159105C (da)
ES (1) ES532079A0 (da)
FI (1) FI80444C (da)
FR (1) FR2545486B1 (da)
GB (1) GB2139621B (da)
GR (1) GR79862B (da)
HU (1) HU191681B (da)
IE (1) IE57393B1 (da)
IL (1) IL71734A (da)
IT (1) IT1206144B (da)
LU (1) LU85344A1 (da)
NL (1) NL8401357A (da)
SE (1) SE454986B (da)
YU (1) YU45900B (da)
ZA (1) ZA843278B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1256M (fr) * 1961-06-26 1962-04-16 M I P Soc Amilloise De Prod Ch Médicament hypocholésterolémiant a base de n-oxyde de l'acide nicotinique.
GB1213162A (en) * 1966-11-16 1970-11-18 Astra Ab Serum lipid lowering pyridine derivatives and their preparation
AT291853B (de) * 1967-03-22 1971-08-10 Buero Patent Ag Automatische, gleislose Förderanlage
US4321268A (en) * 1979-02-08 1982-03-23 Merz & Co. Certain substituted phenyl esters of nicotinic acid, compositions and methods of using same
DE3009099A1 (de) * 1980-03-10 1981-09-17 Merz + Co GmbH & Co, 6000 Frankfurt Neue phenylester der nikotinsaeure und verfahren zu ihrer herstellung
GB2193359B (en) * 1986-07-31 1990-07-11 Multitone Electronics Plc Area communications systems
US4797656A (en) * 1987-01-28 1989-01-10 Keppler Charles N Appliance paging system
US5012749A (en) * 1988-12-27 1991-05-07 The Allen Group Inc. Radio controlled material handling apparatus
US4962377A (en) * 1989-02-09 1990-10-09 Motorola, Inc. Paging by text matching

Also Published As

Publication number Publication date
IE841074L (en) 1984-11-02
HUT34162A (en) 1985-02-28
FI80444B (fi) 1990-02-28
KR860001907B1 (ko) 1986-10-24
IT8420763A0 (it) 1984-05-02
IL71734A0 (en) 1984-09-30
YU74384A (en) 1986-10-31
CS325284A2 (en) 1985-06-13
GB2139621B (en) 1986-10-29
JPS59206357A (ja) 1984-11-22
AU564780B2 (en) 1987-08-27
SE8402297D0 (sv) 1984-04-26
ES8503660A1 (es) 1985-03-16
CS241082B2 (en) 1986-03-13
IT1206144B (it) 1989-04-14
SE8402297L (sv) 1984-11-03
FI80444C (fi) 1990-06-11
GR79862B (da) 1984-10-31
DE3315877A1 (de) 1984-11-08
DK159105C (da) 1991-02-11
IE57393B1 (en) 1992-08-26
FI841736A0 (fi) 1984-05-02
ES532079A0 (es) 1985-03-16
LU85344A1 (fr) 1986-01-29
YU45900B (sh) 1992-09-07
GB8411081D0 (en) 1984-06-06
AU2760484A (en) 1984-11-08
NL8401357A (nl) 1984-12-03
CA1247092A (en) 1988-12-20
US4758581A (en) 1988-07-19
FR2545486A1 (fr) 1984-11-09
IL71734A (en) 1988-02-29
FI841736A (fi) 1984-11-03
DE3315877C2 (da) 1989-11-30
ZA843278B (en) 1985-12-24
KR840009091A (ko) 1984-12-24
DK216484D0 (da) 1984-05-01
DK159105B (da) 1990-09-03
BE899558A (fr) 1984-11-05
GB2139621A (en) 1984-11-14
FR2545486B1 (fr) 1986-12-26
JPS6127389B2 (da) 1986-06-25
CH660005A5 (de) 1987-03-13
SE454986B (sv) 1988-06-13
HU191681B (en) 1987-03-30

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