YU10403A - Kompleksi koji sadrže perfluoralkile sa ostacima šećera, postupci za njihovo dobijanje i njihova primena - Google Patents
Kompleksi koji sadrže perfluoralkile sa ostacima šećera, postupci za njihovo dobijanje i njihova primenaInfo
- Publication number
- YU10403A YU10403A YU10403A YUP10403A YU10403A YU 10403 A YU10403 A YU 10403A YU 10403 A YU10403 A YU 10403A YU P10403 A YUP10403 A YU P10403A YU 10403 A YU10403 A YU 10403A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- perfluoroalkyl
- sugar residues
- producing
- containing complexes
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Kompleksi koji sadrže perfluoralkile sa ostacima šećera opšte formule I u kojoj R predstavlja preko 1-OH ili 1-SH pozicije vezani mono- ili oligosaharidni ostatak Rf znači perfluorisani ugljenični lanac K je metalni kompleks, a Y i Z predstavljaju linker grupe su podesni u intravenoznoj limfografiji, za tumor-dijagnostiku i za vizuelizaciju infarkta i nekroze.[The invention relates to perfluoroalkyl-containing complexes comprising sugar residues of the general formula (I), wherein R represents a mono- or oligosaccharide residue bound in the 1-OH or 1-SH position, Rf represents a perfluorated carbon chain, K is a metal complex and Y and Z are linker groups. The inventive complexes are suitable for use in intravenous lymphography, in tumor diagnosis and for infarct and necrosis imaging.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10040381A DE10040381C1 (de) | 2000-08-11 | 2000-08-11 | Perfluoralkylhaltige Komplexe mit Zuckerresten, Verfahren zu deren Herstellung und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU10403A true YU10403A (sh) | 2006-05-25 |
Family
ID=7652861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU10403A YU10403A (sh) | 2000-08-11 | 2001-07-23 | Kompleksi koji sadrže perfluoralkile sa ostacima šećera, postupci za njihovo dobijanje i njihova primena |
Country Status (31)
| Country | Link |
|---|---|
| EP (1) | EP1307446B1 (sh) |
| JP (1) | JP2004506631A (sh) |
| KR (1) | KR100820387B1 (sh) |
| CN (1) | CN1249058C (sh) |
| AR (1) | AR035579A1 (sh) |
| AT (1) | ATE293623T1 (sh) |
| AU (2) | AU8972901A (sh) |
| BG (1) | BG107540A (sh) |
| BR (1) | BR0113192A (sh) |
| CA (1) | CA2418790A1 (sh) |
| CZ (1) | CZ2003340A3 (sh) |
| DE (2) | DE10040381C1 (sh) |
| DK (1) | DK1307446T3 (sh) |
| EE (1) | EE200300059A (sh) |
| ES (1) | ES2240517T3 (sh) |
| HK (1) | HK1062016A1 (sh) |
| HR (1) | HRP20030172A2 (sh) |
| HU (1) | HUP0300744A3 (sh) |
| IL (1) | IL154328A0 (sh) |
| MX (1) | MXPA03001285A (sh) |
| NO (1) | NO20030648L (sh) |
| NZ (1) | NZ524079A (sh) |
| PL (1) | PL360359A1 (sh) |
| PT (1) | PT1307446E (sh) |
| RU (1) | RU2280644C2 (sh) |
| SK (1) | SK1542003A3 (sh) |
| TW (1) | TWI243170B (sh) |
| UA (1) | UA75364C2 (sh) |
| WO (1) | WO2002014309A1 (sh) |
| YU (1) | YU10403A (sh) |
| ZA (1) | ZA200301948B (sh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19948651B4 (de) * | 1999-09-29 | 2006-10-05 | Schering Ag | Para- und diamagnetische perfluorhaltige Verbindungen enthaltende galenische Formulierungen, deren Herstellung und Verwendung |
| US7344704B2 (en) | 2002-07-10 | 2008-03-18 | Schering Ag | Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi |
| DE10231799B4 (de) * | 2002-07-10 | 2006-10-05 | Schering Ag | Verwendung von perfluoralkylhaltigen Metallkomplexen als Kontrastmittel im MR-Imaging zur Darstellung von Intravasalen Thromben |
| DE10260372B4 (de) | 2002-12-13 | 2007-01-04 | Schering Ag | Kernspintomographievorrichtung und Verfahren zur ortsaufgelösten Bilddarstellung |
| EP1904462A2 (de) * | 2005-07-15 | 2008-04-02 | Bayer Schering Pharma Aktiengesellschaft | Perfluoralkylhaltige komplexe, verfahren zu deren herstellung, sowie deren verwendung |
| DE102006049821A1 (de) | 2006-10-18 | 2008-04-24 | Bayer Schering Pharma Aktiengesellschaft | Metallchelate mit perfluoriertem PEG-Rest, Verfahren zu deren Herstellung, sowie deren Verwendung |
| JP2010507645A (ja) * | 2006-10-25 | 2010-03-11 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 前立腺癌を検出するための造影剤 |
| DE102008024976A1 (de) | 2008-05-23 | 2009-12-17 | Marvis Technologies Gmbh | Medizinisches Instrument |
| JP2011190183A (ja) * | 2010-03-11 | 2011-09-29 | Noguchi Institute | フルオラス化糖結合型クラウンエーテル誘導体 |
| EP2450067A1 (en) | 2010-10-18 | 2012-05-09 | MaRVis Technologies GmbH | Medical device |
| EP2484388A1 (en) | 2011-02-05 | 2012-08-08 | MaRVis Technologies GmbH | Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it |
| EP2692365A1 (en) | 2012-08-03 | 2014-02-05 | MaRVis Medical GmbH | Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it |
| EP3101012A1 (en) | 2015-06-04 | 2016-12-07 | Bayer Pharma Aktiengesellschaft | New gadolinium chelate compounds for use in magnetic resonance imaging |
| CN110035996B (zh) | 2016-11-28 | 2022-08-09 | 拜耳医药股份公司 | 用于磁共振成像的新型高弛豫性钆螯合物 |
| KR20210095168A (ko) | 2018-11-23 | 2021-07-30 | 바이엘 악티엔게젤샤프트 | 조영 매체의 제형 및 그의 제조 방법 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5707604A (en) * | 1986-11-18 | 1998-01-13 | Access Pharmaceuticals, Inc. | Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles |
| AU623901B2 (en) * | 1988-01-26 | 1992-05-28 | Nycomed As | Paramagnetic compounds comprising chelating moiety, linker group macro molecule and paramagnetic metal |
| ES2116291T3 (es) * | 1989-10-23 | 1998-07-16 | Nycomed Salutar Inc | Agentes quelantes de metales en sitios multiples. |
| US5330743A (en) * | 1992-11-12 | 1994-07-19 | Magnetic Research, Inc. | Aminosaccharide contrast agents for magnetic resonance images |
| CA2160819A1 (en) * | 1994-10-21 | 1996-04-22 | Yuji Hashiguchi | Diagnostic imaging agent |
| DE19603033A1 (de) * | 1996-01-19 | 1997-07-24 | Schering Ag | Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
| DE19728954C1 (de) * | 1997-06-30 | 1999-04-22 | Schering Ag | Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DE19729013A1 (de) * | 1997-07-03 | 1999-02-04 | Schering Ag | Oligomere, perfluoralkylhaltige Verbindungen, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik |
| DE19744004C1 (de) * | 1997-09-26 | 1999-07-22 | Schering Ag | Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging |
| DE19758105A1 (de) * | 1997-12-18 | 1999-06-24 | Schering Ag | Dendritische Polymer-Saccharid-Konjugate, diese enthaltende pharmazeutische Mittel, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DE19914101C1 (de) * | 1999-03-22 | 2000-10-12 | Schering Ag | Perfluoralkylamide, ihre Herstellung und ihre Verwendung in der Diagnostik |
| DE19948651B4 (de) * | 1999-09-29 | 2006-10-05 | Schering Ag | Para- und diamagnetische perfluorhaltige Verbindungen enthaltende galenische Formulierungen, deren Herstellung und Verwendung |
-
2000
- 2000-08-11 DE DE10040381A patent/DE10040381C1/de not_active Expired - Fee Related
-
2001
- 2001-07-23 RU RU2003105815/04A patent/RU2280644C2/ru not_active IP Right Cessation
- 2001-07-23 AU AU8972901A patent/AU8972901A/xx active Pending
- 2001-07-23 ES ES01969481T patent/ES2240517T3/es not_active Expired - Lifetime
- 2001-07-23 HU HU0300744A patent/HUP0300744A3/hu unknown
- 2001-07-23 EE EEP200300059A patent/EE200300059A/xx unknown
- 2001-07-23 SK SK154-2003A patent/SK1542003A3/sk unknown
- 2001-07-23 CN CNB018171109A patent/CN1249058C/zh not_active Expired - Fee Related
- 2001-07-23 WO PCT/EP2001/008499 patent/WO2002014309A1/de active IP Right Grant
- 2001-07-23 AT AT01969481T patent/ATE293623T1/de not_active IP Right Cessation
- 2001-07-23 CZ CZ2003340A patent/CZ2003340A3/cs unknown
- 2001-07-23 PT PT01969481T patent/PT1307446E/pt unknown
- 2001-07-23 UA UA2003032069A patent/UA75364C2/uk unknown
- 2001-07-23 NZ NZ524079A patent/NZ524079A/en unknown
- 2001-07-23 KR KR1020037002021A patent/KR100820387B1/ko not_active IP Right Cessation
- 2001-07-23 PL PL01360359A patent/PL360359A1/xx not_active Application Discontinuation
- 2001-07-23 EP EP01969481A patent/EP1307446B1/de not_active Expired - Lifetime
- 2001-07-23 MX MXPA03001285A patent/MXPA03001285A/es active IP Right Grant
- 2001-07-23 AU AU2001289729A patent/AU2001289729B2/en not_active Ceased
- 2001-07-23 JP JP2002519449A patent/JP2004506631A/ja active Pending
- 2001-07-23 BR BR0113192-3A patent/BR0113192A/pt not_active IP Right Cessation
- 2001-07-23 CA CA002418790A patent/CA2418790A1/en not_active Abandoned
- 2001-07-23 IL IL15432801A patent/IL154328A0/xx unknown
- 2001-07-23 DE DE50105965T patent/DE50105965D1/de not_active Expired - Fee Related
- 2001-07-23 DK DK01969481T patent/DK1307446T3/da active
- 2001-07-23 YU YU10403A patent/YU10403A/sh unknown
- 2001-08-10 TW TW090119623A patent/TWI243170B/zh not_active IP Right Cessation
- 2001-08-10 AR ARP010103831A patent/AR035579A1/es unknown
-
2003
- 2003-02-07 BG BG107540A patent/BG107540A/bg unknown
- 2003-02-10 NO NO20030648A patent/NO20030648L/no not_active Application Discontinuation
- 2003-03-10 HR HR20030172A patent/HRP20030172A2/hr not_active Application Discontinuation
- 2003-03-10 ZA ZA200301948A patent/ZA200301948B/en unknown
-
2004
- 2004-07-13 HK HK04105095A patent/HK1062016A1/xx not_active IP Right Cessation
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