WO2012088116A3 - Analogues du glucagon présentant une activité de récepteur de gip - Google Patents
Analogues du glucagon présentant une activité de récepteur de gip Download PDFInfo
- Publication number
- WO2012088116A3 WO2012088116A3 PCT/US2011/066164 US2011066164W WO2012088116A3 WO 2012088116 A3 WO2012088116 A3 WO 2012088116A3 US 2011066164 W US2011066164 W US 2011066164W WO 2012088116 A3 WO2012088116 A3 WO 2012088116A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gip receptor
- receptor activity
- glucagon analogs
- analogs exhibiting
- exhibiting gip
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG2013046412A SG191194A1 (en) | 2010-12-22 | 2011-12-20 | Glucagon analogs exhibiting gip receptor activity |
CN201180068157.2A CN103458920B (zh) | 2010-12-22 | 2011-12-20 | 表现出gip受体活性的胰高血糖素类似物 |
EA201390941A EA201390941A1 (ru) | 2010-12-22 | 2011-12-20 | Аналоги глюкагона, проявляющие активность на рецепторе gip |
BR112013015389A BR112013015389A2 (pt) | 2010-12-22 | 2011-12-20 | análogo de glucagon exibindo atividade de receptor gip |
MA36136A MA34885B1 (fr) | 2010-12-22 | 2011-12-20 | Analogues du glucagon presentant una ctivite de recepteur de gip |
ES11808086T ES2713952T3 (es) | 2010-12-22 | 2011-12-20 | Análogos de glucagón que muestran actividad de receptor de GIP |
JP2013546329A JP6086067B2 (ja) | 2010-12-22 | 2011-12-20 | Gipレセプター活性を示すグルカゴンアナローグ |
EP11808086.0A EP2654773B1 (fr) | 2010-12-22 | 2011-12-20 | Analogues du glucagon présentant une activité de récepteur de gip |
AU2011349331A AU2011349331A1 (en) | 2010-12-22 | 2011-12-20 | Glucagon analogs exhibiting GIP receptor activity |
KR1020137018994A KR20130132931A (ko) | 2010-12-22 | 2011-12-20 | Gip 수용체 활성을 나타내는 글루카곤 유사체들 |
CA2821766A CA2821766A1 (fr) | 2010-12-22 | 2011-12-20 | Analogues du glucagon presentant une activite de recepteur de gip |
MX2013006304A MX2013006304A (es) | 2010-12-22 | 2011-12-20 | Analogos de glucagon que exhiben actividad del receptor gip. |
NZ612297A NZ612297A (en) | 2010-12-22 | 2011-12-20 | Glucagon analogs exhibiting gip receptor activity |
ECSP13012697 ECSP13012697A (es) | 2010-12-22 | 2013-06-18 | Análogos de glucagón que presentan actividad de receptor de gip |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201061426285P | 2010-12-22 | 2010-12-22 | |
US61/426,285 | 2010-12-22 | ||
US201161514609P | 2011-08-03 | 2011-08-03 | |
US61/514,609 | 2011-08-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2012088116A2 WO2012088116A2 (fr) | 2012-06-28 |
WO2012088116A3 true WO2012088116A3 (fr) | 2012-11-15 |
Family
ID=45476658
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2011/066164 WO2012088116A2 (fr) | 2010-12-22 | 2011-12-20 | Analogues du glucagon présentant une activité de récepteur de gip |
Country Status (21)
Country | Link |
---|---|
US (4) | US8507428B2 (fr) |
EP (1) | EP2654773B1 (fr) |
JP (1) | JP6086067B2 (fr) |
KR (1) | KR20130132931A (fr) |
CN (1) | CN103458920B (fr) |
AR (1) | AR084459A1 (fr) |
AU (1) | AU2011349331A1 (fr) |
BR (1) | BR112013015389A2 (fr) |
CA (1) | CA2821766A1 (fr) |
CL (1) | CL2013001783A1 (fr) |
CO (1) | CO6761302A2 (fr) |
CR (1) | CR20130295A (fr) |
EA (1) | EA201390941A1 (fr) |
EC (1) | ECSP13012697A (fr) |
ES (1) | ES2713952T3 (fr) |
MA (1) | MA34885B1 (fr) |
MX (1) | MX2013006304A (fr) |
NZ (1) | NZ612297A (fr) |
PE (1) | PE20140186A1 (fr) |
SG (1) | SG191194A1 (fr) |
WO (1) | WO2012088116A2 (fr) |
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US8546327B2 (en) | 2008-06-17 | 2013-10-01 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
MX2011013625A (es) | 2009-06-16 | 2012-01-20 | Univ Indiana Res & Tech Corp | Compuestos glucagon activo de receptor de gip. |
RU2012136450A (ru) * | 2010-01-27 | 2014-03-10 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Конъюгаты антагонист глюкагона - агонист gip и композиции для лечения метаболических расстройств и ожирения |
AR084558A1 (es) | 2010-12-22 | 2013-05-22 | Marcadia Biotech | Metodos para tratar trastornos metabolicos y obesidad con peptidos basados en glucagon activos para el receptor de peptido insulinotropico dependiente de glucosa (gip)/peptido-1 similar al glucagon (glp-1) |
MA34885B1 (fr) * | 2010-12-22 | 2014-02-01 | Indiana Unversity Res And Technology Corp | Analogues du glucagon presentant una ctivite de recepteur de gip |
LT2723367T (lt) | 2011-06-22 | 2017-08-25 | Indiana University Research And Technology Corporation | Bendri gliukagono/glp-1 receptoriaus agonistai |
TWI596110B (zh) | 2011-09-23 | 2017-08-21 | 諾佛 儂迪克股份有限公司 | 新穎升糖素類似物 |
RU2015101697A (ru) | 2012-06-21 | 2016-08-10 | Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн | Аналоги глюкагона, обладающие активностью рецептора gip |
UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
KR102213907B1 (ko) | 2012-11-20 | 2021-02-09 | 메더리스 다이어비티즈, 엘엘씨 | 인슐린 저항성에 대한 개선된 펩티드 약제 |
ES2688367T3 (es) | 2012-12-21 | 2018-11-02 | Sanofi | Derivados de exendina-4 como agonistas duales de GLP1/GIP o trigonales de GLP1/GIP/glucagón |
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US20160058881A1 (en) * | 2013-03-15 | 2016-03-03 | Indiana University Research And Technology Corporation | Prodrugs with prolonged action |
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- 2011-12-20 WO PCT/US2011/066164 patent/WO2012088116A2/fr active Application Filing
- 2011-12-20 CA CA2821766A patent/CA2821766A1/fr not_active Abandoned
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Also Published As
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EA201390941A1 (ru) | 2013-12-30 |
CA2821766A1 (fr) | 2012-06-28 |
NZ612297A (en) | 2015-10-30 |
KR20130132931A (ko) | 2013-12-05 |
CL2013001783A1 (es) | 2014-01-24 |
US20120238493A1 (en) | 2012-09-20 |
JP2014507402A (ja) | 2014-03-27 |
AU2011349331A1 (en) | 2013-07-11 |
ECSP13012697A (es) | 2013-10-31 |
PE20140186A1 (es) | 2014-02-13 |
CR20130295A (es) | 2013-10-09 |
US20130116173A1 (en) | 2013-05-09 |
EP2654773A2 (fr) | 2013-10-30 |
CN103458920B (zh) | 2016-07-06 |
CO6761302A2 (es) | 2013-09-30 |
SG191194A1 (en) | 2013-07-31 |
US9587005B2 (en) | 2017-03-07 |
MA34885B1 (fr) | 2014-02-01 |
ES2713952T3 (es) | 2019-05-24 |
EP2654773B1 (fr) | 2018-10-03 |
MX2013006304A (es) | 2013-07-02 |
US20150259393A1 (en) | 2015-09-17 |
CN103458920A (zh) | 2013-12-18 |
US8507428B2 (en) | 2013-08-13 |
WO2012088116A2 (fr) | 2012-06-28 |
US20160115215A1 (en) | 2016-04-28 |
US9249206B2 (en) | 2016-02-02 |
AR084459A1 (es) | 2013-05-15 |
BR112013015389A2 (pt) | 2016-11-22 |
JP6086067B2 (ja) | 2017-03-01 |
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