TW201241006A - Glucagon analogs exhibiting GIP receptor activity - Google Patents

Glucagon analogs exhibiting GIP receptor activity

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Publication number
TW201241006A
TW201241006A TW100147859A TW100147859A TW201241006A TW 201241006 A TW201241006 A TW 201241006A TW 100147859 A TW100147859 A TW 100147859A TW 100147859 A TW100147859 A TW 100147859A TW 201241006 A TW201241006 A TW 201241006A
Authority
TW
Taiwan
Prior art keywords
gip receptor
receptor activity
glucagon analogs
analogs exhibiting
exhibiting gip
Prior art date
Application number
TW100147859A
Other languages
Chinese (zh)
Inventor
Richard D Dimarchi
Brian P Ward
Original Assignee
Univ Indiana Res & Tech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Indiana Res & Tech Corp filed Critical Univ Indiana Res & Tech Corp
Publication of TW201241006A publication Critical patent/TW201241006A/en

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Abstract

Provided herein are glucagon analogs which exhibit potent activity at the GIP receptor, and, as such are contemplated for use in treating diabetes and obesity. In exemplary embodiments, the glucagon analog of the present disclosures exhibit an EC50 at the GIP receptor which is within the nanomolar or picomolar range.
TW100147859A 2010-12-22 2011-12-21 Glucagon analogs exhibiting GIP receptor activity TW201241006A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42628510P 2010-12-22 2010-12-22
US201161514609P 2011-08-03 2011-08-03

Publications (1)

Publication Number Publication Date
TW201241006A true TW201241006A (en) 2012-10-16

Family

ID=47599973

Family Applications (1)

Application Number Title Priority Date Filing Date
TW100147859A TW201241006A (en) 2010-12-22 2011-12-21 Glucagon analogs exhibiting GIP receptor activity

Country Status (1)

Country Link
TW (1) TW201241006A (en)

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