UY32384A - Nuevas bencenosulfonamidas como bloqueadores de canales de calcio - Google Patents

Nuevas bencenosulfonamidas como bloqueadores de canales de calcio

Info

Publication number
UY32384A
UY32384A UY0001032384A UY32384A UY32384A UY 32384 A UY32384 A UY 32384A UY 0001032384 A UY0001032384 A UY 0001032384A UY 32384 A UY32384 A UY 32384A UY 32384 A UY32384 A UY 32384A
Authority
UY
Uruguay
Prior art keywords
calcium channel
bencenosulphonamids
new
channel blockers
formula
Prior art date
Application number
UY0001032384A
Other languages
English (en)
Spanish (es)
Inventor
Andrew O Stewart
Xia Zhiren
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41796157&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY32384(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of UY32384A publication Critical patent/UY32384A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Addiction (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
UY0001032384A 2009-01-15 2010-01-15 Nuevas bencenosulfonamidas como bloqueadores de canales de calcio UY32384A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14489909P 2009-01-15 2009-01-15

Publications (1)

Publication Number Publication Date
UY32384A true UY32384A (es) 2010-08-31

Family

ID=41796157

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001032384A UY32384A (es) 2009-01-15 2010-01-15 Nuevas bencenosulfonamidas como bloqueadores de canales de calcio

Country Status (22)

Country Link
US (3) US8101614B2 (enExample)
EP (1) EP2382191B1 (enExample)
JP (1) JP5619773B2 (enExample)
KR (1) KR20110110299A (enExample)
CN (1) CN102282131B (enExample)
AR (1) AR077440A1 (enExample)
AU (1) AU2010204753A1 (enExample)
BR (1) BRPI1005675A2 (enExample)
CA (1) CA2747752A1 (enExample)
CL (1) CL2011001714A1 (enExample)
CO (1) CO6400194A2 (enExample)
DO (1) DOP2011000217A (enExample)
ES (1) ES2527467T3 (enExample)
IL (1) IL213500A0 (enExample)
MX (1) MX337190B (enExample)
PE (1) PE20120126A1 (enExample)
RU (1) RU2011134052A (enExample)
SG (1) SG172308A1 (enExample)
TW (1) TW201028421A (enExample)
UY (1) UY32384A (enExample)
WO (1) WO2010083264A1 (enExample)
ZA (1) ZA201104715B (enExample)

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CN104352492B (zh) 2008-04-24 2017-12-05 Msd K.K.公司 以芳基磺酰基衍生物作为有效成分的长链脂肪酸延长酶抑制剂
TW201028421A (en) * 2009-01-15 2010-08-01 Abbott Lab Novel benzenesulfonamides as calcium channel blockers
AU2012308243B2 (en) * 2011-09-15 2017-09-14 Taipei Medical University Use of indolyl and indolinyl hydroxamates for treating heart failure of neuronal injury
UY34349A (es) 2011-09-29 2013-04-05 Abb Vie Inc OCTAHIDROPIRROLO[1,2-a]PIRAZINA SULFONAMIDAS SUSTITUIDAS COMO BLOQUEADORES DE CANALES DE CALCIO
WO2013049164A1 (en) 2011-09-29 2013-04-04 Abbvie Inc. SUBSTITUTED OCTAHYDROPYRROLO[1,2-a]PYRAZINES AS CALCIUM CHANNEL BLOCKERS
US20130178477A1 (en) * 2012-01-05 2013-07-11 Abbvie Inc. Methods of treating diabetic neuropathy using benzenesulfonamides
AU2013359533A1 (en) * 2012-12-12 2015-05-28 Abbvie, Inc. Diazepine derivatives useful as calcium channel blockers in the treatment of pain
RU2727516C2 (ru) 2013-09-10 2020-07-22 Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем Терапевтические средства, нацеленные на укороченные белки аденоматозного полипоза толстого кишечника (арс)
WO2015051336A1 (en) 2013-10-03 2015-04-09 David Wise Compositions and methods for treating pelvic pain and other conditions
US10082496B2 (en) 2014-09-10 2018-09-25 Board Of Regents Of The University Of Texas System Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
EP3364993B1 (en) 2015-10-22 2022-11-09 Cavion, Inc. Methods for treating angelman syndrome
CN110545806A (zh) 2017-02-15 2019-12-06 卡维昂公司 钙通道抑制剂
EP3615521A4 (en) 2017-04-26 2021-02-17 Cavion, Inc. METHODS FOR IMPROVING MEMORY AND COGNITION AND TREATING MEMORY AND COGNITIVE DISORDERS
AU2019207491A1 (en) 2018-01-10 2020-07-30 Cura Therapeutics, Llc Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications
US11858910B2 (en) 2018-08-24 2024-01-02 Sunshine Lake Pharma Co., Ltd. Pyridinylmethylenepiperidine derivatives and uses thereof
JP7480131B2 (ja) 2018-10-03 2024-05-09 カビオン・インコーポレイテッド （ｒ）－２－（４－イソプロピルフェニル）－ｎ－（１－（５－（２，２，２－トリフルオロエトキシ）ピリジン－２－イル）エチル）アセトアミドを使用した本態性振戦の処置
US20200131156A1 (en) * 2018-10-30 2020-04-30 H. Lundbeck A/S ARYLSULFONYLPYROLECARBOXAMIDE DERIVATIVES AS Kv3 POTASSIUM CHANNEL ACTIVATORS
WO2021007478A1 (en) * 2019-07-11 2021-01-14 Cura Therapeutics, Llc Sulfone compounds and pharmaceutical compositions thereof, and their therapeutic applications for the treatment of neurodegenerative diseases
WO2021007487A1 (en) 2019-07-11 2021-01-14 Praxis Precision Medicines, Inc. Formulations of t-type calcium channel modulators and methods of use thereof
CN117229257B (zh) * 2022-06-06 2026-01-30 中国药科大学 间氨磺酰苯甲酰胺类化合物及制法、药物组合物和应用
WO2025255502A1 (en) 2024-06-07 2025-12-11 Cavion, Inc. PYRIDYL AMIDE Cav3 CHANNEL MODULATORS

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ATE269848T1 (de) 1999-04-07 2004-07-15 Univ Virginia Calciumkanalblocker als antikrebsmittel
TW200503994A (en) 2003-01-24 2005-02-01 Novartis Ag Organic compounds
US7223754B2 (en) 2003-03-10 2007-05-29 Dynogen Pharmaceuticals, Inc. Thiazolidinone, oxazolidinone, and imidazolone derivatives for treating lower urinary tract and related disorders
DE602004027171D1 (de) * 2003-04-11 2010-06-24 High Point Pharmaceuticals Llc Verbindungen mit Aktivität an der 11Beta-Hydroxasteroiddehydrogenase
JP2006523707A (ja) * 2003-04-15 2006-10-19 アストラゼネカ アクツィエボラーグ 治療化合物
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KR20100033981A (ko) * 2007-06-03 2010-03-31 벤더르빌트 유니버시티 벤즈아미드 대사성 글루타민산염 수용체5 양성 알로스테릭 조절자 및 이의 제조 및 사용방법
CN104352492B (zh) 2008-04-24 2017-12-05 Msd K.K.公司 以芳基磺酰基衍生物作为有效成分的长链脂肪酸延长酶抑制剂
TW201028421A (en) * 2009-01-15 2010-08-01 Abbott Lab Novel benzenesulfonamides as calcium channel blockers

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ES2527467T3 (es) 2015-01-26
JP5619773B2 (ja) 2014-11-05
US8741899B2 (en) 2014-06-03
AU2010204753A1 (en) 2011-08-11
BRPI1005675A2 (pt) 2017-06-13
JP2012515209A (ja) 2012-07-05
WO2010083264A1 (en) 2010-07-22
EP2382191A1 (en) 2011-11-02
MX337190B (es) 2016-02-16
TW201028421A (en) 2010-08-01
US20100197693A1 (en) 2010-08-05
US8101614B2 (en) 2012-01-24
PE20120126A1 (es) 2012-03-18
MX2011007496A (es) 2011-08-04
US20120083499A1 (en) 2012-04-05
SG172308A1 (en) 2011-07-28
RU2011134052A (ru) 2013-02-20
US20130210827A1 (en) 2013-08-15
KR20110110299A (ko) 2011-10-06
ZA201104715B (en) 2014-01-29
DOP2011000217A (es) 2011-07-31
CA2747752A1 (en) 2010-07-22
EP2382191B1 (en) 2014-11-12
CO6400194A2 (es) 2012-03-15
US8404719B2 (en) 2013-03-26
CL2011001714A1 (es) 2011-11-11
CN102282131A (zh) 2011-12-14
CN102282131B (zh) 2015-08-26
AR077440A1 (es) 2011-08-31
IL213500A0 (en) 2011-07-31

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