BRPI1005675A2 - benzenossulfonamidas bloqueadoras dos canais de cálcio - Google Patents
benzenossulfonamidas bloqueadoras dos canais de cálcioInfo
- Publication number
- BRPI1005675A2 BRPI1005675A2 BRPI1005675A BRPI1005675A BRPI1005675A2 BR PI1005675 A2 BRPI1005675 A2 BR PI1005675A2 BR PI1005675 A BRPI1005675 A BR PI1005675A BR PI1005675 A BRPI1005675 A BR PI1005675A BR PI1005675 A2 BRPI1005675 A2 BR PI1005675A2
- Authority
- BR
- Brazil
- Prior art keywords
- benzenesulfonamides
- calcium channel
- channel blocking
- blocking
- calcium
- Prior art date
Links
- 150000008331 benzenesulfonamides Chemical class 0.000 title 1
- 230000008061 calcium-channel-blocking effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
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- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A61P17/04—Antipruritics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Gynecology & Obstetrics (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Pregnancy & Childbirth (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14489909P | 2009-01-15 | 2009-01-15 | |
PCT/US2010/020964 WO2010083264A1 (en) | 2009-01-15 | 2010-01-14 | Novel benzenesulfonamides as calcium channel blockers |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1005675A2 true BRPI1005675A2 (pt) | 2017-06-13 |
Family
ID=41796157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1005675A BRPI1005675A2 (pt) | 2009-01-15 | 2010-01-14 | benzenossulfonamidas bloqueadoras dos canais de cálcio |
Country Status (22)
Country | Link |
---|---|
US (3) | US8101614B2 (pt) |
EP (1) | EP2382191B1 (pt) |
JP (1) | JP5619773B2 (pt) |
KR (1) | KR20110110299A (pt) |
CN (1) | CN102282131B (pt) |
AR (1) | AR077440A1 (pt) |
AU (1) | AU2010204753A1 (pt) |
BR (1) | BRPI1005675A2 (pt) |
CA (1) | CA2747752A1 (pt) |
CL (1) | CL2011001714A1 (pt) |
CO (1) | CO6400194A2 (pt) |
DO (1) | DOP2011000217A (pt) |
ES (1) | ES2527467T3 (pt) |
IL (1) | IL213500A0 (pt) |
MX (1) | MX337190B (pt) |
PE (1) | PE20120126A1 (pt) |
RU (1) | RU2011134052A (pt) |
SG (1) | SG172308A1 (pt) |
TW (1) | TW201028421A (pt) |
UY (1) | UY32384A (pt) |
WO (1) | WO2010083264A1 (pt) |
ZA (1) | ZA201104715B (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009131065A1 (ja) | 2008-04-24 | 2009-10-29 | 萬有製薬株式会社 | アリールスルホニル誘導体を有効成分とする長鎖脂肪酸伸長酵素阻害剤 |
TW201028421A (en) * | 2009-01-15 | 2010-08-01 | Abbott Lab | Novel benzenesulfonamides as calcium channel blockers |
TWI464147B (zh) * | 2011-09-15 | 2014-12-11 | Univ Taipei Medical | 吲哚氫胺酸和吲哚啉氫胺酸於治療心臟衰竭或神經損傷的用途 |
AR088064A1 (es) * | 2011-09-29 | 2014-05-07 | Abbvie Inc | Octahidropirrolo[1,2-a]pirazina sulfonamidas sustituidas como bloqueadores de canales de calcio |
US8669255B2 (en) | 2011-09-29 | 2014-03-11 | Abbvie Inc. | Substituted octahydropyrrolo[1,2-a]pyrazines as calcium channel blockers |
WO2013103867A1 (en) | 2012-01-05 | 2013-07-11 | Abbvie Inc. | Benzenesulfonamide derivative for use in the treatment of diabetic neuropathy |
KR20150093237A (ko) | 2012-12-12 | 2015-08-17 | 애브비 인코포레이티드 | 통증 치료시 칼슘 채널 차단제로서 유용한 디아제핀 유도체 |
EP3044218B1 (en) * | 2013-09-10 | 2020-05-27 | Board Of Regents Of the University Of Texas System | Therapeutics targeting truncated adenomatous polyposis coli (apc) proteins |
WO2015051336A1 (en) * | 2013-10-03 | 2015-04-09 | David Wise | Compositions and methods for treating pelvic pain and other conditions |
US10082496B2 (en) | 2014-09-10 | 2018-09-25 | Board Of Regents Of The University Of Texas System | Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis |
DK3364993T3 (da) | 2015-10-22 | 2023-01-09 | Cavion Inc | Fremgangsmåder til behandling af angelman syndrom |
US11130750B2 (en) | 2017-02-15 | 2021-09-28 | Cavion, Inc. | Calcium channel inhibitors |
MX2019012818A (es) | 2017-04-26 | 2020-07-14 | Cavion Inc | Metodos para mejorar la memoria y la cognicion y para el tratamiento de trastornos de la memoria y cognitivos. |
AU2019207491A1 (en) | 2018-01-10 | 2020-07-30 | Cura Therapeutics, Llc | Pharmaceutical compositions comprising phenylsulfonamides, and their therapeutic applications |
JP7405834B2 (ja) | 2018-08-24 | 2023-12-26 | サンシャイン・レイク・ファーマ・カンパニー・リミテッド | ピリジニルメチレンピペリジン誘導体及びその使用 |
CN113164393A (zh) | 2018-10-03 | 2021-07-23 | 卡维昂公司 | 使用(r)-2-(4-异丙基苯基)-n-(1-(5-(2,2,2-三氟乙氧基)吡啶-2-基)乙基)乙酰胺治疗原发性震颤 |
US20200131156A1 (en) * | 2018-10-30 | 2020-04-30 | H. Lundbeck A/S | ARYLSULFONYLPYROLECARBOXAMIDE DERIVATIVES AS Kv3 POTASSIUM CHANNEL ACTIVATORS |
CN114340670A (zh) | 2019-07-11 | 2022-04-12 | 普拉克西斯精密药物股份有限公司 | T-型钙通道调节剂的制剂及其使用方法 |
EP3997068A1 (en) * | 2019-07-11 | 2022-05-18 | Cura Therapeutics, LLC | Sulfone compounds and pharmaceutical compositions thereof, and their therapeutic applications for the treatment of neurodegenerative diseases |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1165508B1 (en) | 1999-04-07 | 2004-06-23 | The University of Virginia Patent Foundation | Anticancer calcium channel blockers |
TW200503994A (en) * | 2003-01-24 | 2005-02-01 | Novartis Ag | Organic compounds |
US7223754B2 (en) | 2003-03-10 | 2007-05-29 | Dynogen Pharmaceuticals, Inc. | Thiazolidinone, oxazolidinone, and imidazolone derivatives for treating lower urinary tract and related disorders |
ATE467616T1 (de) * | 2003-04-11 | 2010-05-15 | High Point Pharmaceuticals Llc | Verbindungen mit aktivität an der 11beta- hydroxasteroiddehydrogenase |
ATE387435T1 (de) * | 2003-04-15 | 2008-03-15 | Astrazeneca Ab | Substituirte benzosulfonamide als potenzierungsmittel von glutamatrezeptoren |
JP5140577B2 (ja) * | 2005-03-31 | 2013-02-06 | タケダ カリフォルニア インコーポレイテッド | ヒドロキシステロイドデヒドロゲナーゼ阻害剤 |
WO2007052843A1 (ja) * | 2005-11-04 | 2007-05-10 | Takeda Pharmaceutical Company Limited | 複素環アミド化合物およびその用途 |
US20100105682A1 (en) * | 2006-10-13 | 2010-04-29 | Hassan Pajouhesh | Cyclopropyl-piperazine compounds as calcium channel blockers |
MX2009013169A (es) * | 2007-06-03 | 2010-04-30 | Univ Vanderbilt | Moduladores alostericos positivos del mglur5 benzamida y metodos de elaboracion y uso de los mismos. |
WO2009131065A1 (ja) * | 2008-04-24 | 2009-10-29 | 萬有製薬株式会社 | アリールスルホニル誘導体を有効成分とする長鎖脂肪酸伸長酵素阻害剤 |
TW201028421A (en) * | 2009-01-15 | 2010-08-01 | Abbott Lab | Novel benzenesulfonamides as calcium channel blockers |
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2009
- 2009-12-31 TW TW098146447A patent/TW201028421A/zh unknown
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2010
- 2010-01-14 PE PE2011001348A patent/PE20120126A1/es not_active Application Discontinuation
- 2010-01-14 EP EP10701070.4A patent/EP2382191B1/en active Active
- 2010-01-14 KR KR1020117018567A patent/KR20110110299A/ko not_active Application Discontinuation
- 2010-01-14 US US12/687,465 patent/US8101614B2/en not_active Expired - Fee Related
- 2010-01-14 BR BRPI1005675A patent/BRPI1005675A2/pt not_active IP Right Cessation
- 2010-01-14 WO PCT/US2010/020964 patent/WO2010083264A1/en active Application Filing
- 2010-01-14 CA CA2747752A patent/CA2747752A1/en active Pending
- 2010-01-14 CN CN201080004675.3A patent/CN102282131B/zh not_active Expired - Fee Related
- 2010-01-14 RU RU2011134052/04A patent/RU2011134052A/ru not_active Application Discontinuation
- 2010-01-14 ES ES10701070.4T patent/ES2527467T3/es active Active
- 2010-01-14 SG SG2011045564A patent/SG172308A1/en unknown
- 2010-01-14 MX MX2011007496A patent/MX337190B/es active IP Right Grant
- 2010-01-14 AU AU2010204753A patent/AU2010204753A1/en not_active Abandoned
- 2010-01-14 JP JP2011546319A patent/JP5619773B2/ja not_active Expired - Fee Related
- 2010-01-15 UY UY0001032384A patent/UY32384A/es not_active Application Discontinuation
- 2010-01-15 AR ARP100100091A patent/AR077440A1/es not_active Application Discontinuation
-
2011
- 2011-06-12 IL IL213500A patent/IL213500A0/en unknown
- 2011-06-24 ZA ZA2011/04715A patent/ZA201104715B/en unknown
- 2011-07-07 DO DO2011000217A patent/DOP2011000217A/es unknown
- 2011-07-14 CL CL2011001714A patent/CL2011001714A1/es unknown
- 2011-08-02 CO CO11097206A patent/CO6400194A2/es not_active Application Discontinuation
- 2011-12-12 US US13/323,029 patent/US8404719B2/en active Active
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2013
- 2013-02-04 US US13/758,615 patent/US8741899B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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US8101614B2 (en) | 2012-01-24 |
AR077440A1 (es) | 2011-08-31 |
CO6400194A2 (es) | 2012-03-15 |
IL213500A0 (en) | 2011-07-31 |
TW201028421A (en) | 2010-08-01 |
JP2012515209A (ja) | 2012-07-05 |
KR20110110299A (ko) | 2011-10-06 |
CN102282131A (zh) | 2011-12-14 |
CA2747752A1 (en) | 2010-07-22 |
RU2011134052A (ru) | 2013-02-20 |
US8741899B2 (en) | 2014-06-03 |
SG172308A1 (en) | 2011-07-28 |
US20120083499A1 (en) | 2012-04-05 |
MX337190B (es) | 2016-02-16 |
AU2010204753A1 (en) | 2011-08-11 |
ES2527467T3 (es) | 2015-01-26 |
CL2011001714A1 (es) | 2011-11-11 |
PE20120126A1 (es) | 2012-03-18 |
MX2011007496A (es) | 2011-08-04 |
ZA201104715B (en) | 2014-01-29 |
JP5619773B2 (ja) | 2014-11-05 |
UY32384A (es) | 2010-08-31 |
US20100197693A1 (en) | 2010-08-05 |
WO2010083264A1 (en) | 2010-07-22 |
CN102282131B (zh) | 2015-08-26 |
DOP2011000217A (es) | 2011-07-31 |
EP2382191B1 (en) | 2014-11-12 |
US8404719B2 (en) | 2013-03-26 |
EP2382191A1 (en) | 2011-11-02 |
US20130210827A1 (en) | 2013-08-15 |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B25B | Requested transfer of rights rejected |
Owner name: ABBOTT LABORATORIES (US) Free format text: INDEFERIDO O PEDIDO DE TRANSFERENCIA CONTIDO NA PETICAO 020130078249 DE 25/09/2013, CONFORME DISPOSTO NO ART. 59 DA LEI 9279 DE 14/05/1996, PELO FATO DO PEDIDO DE PATENTE TER SIDO ARQUIVADO DEFINITIVAMENTE NA RPI 2442 DE 24/10/2017. Owner name: ABBOTT LABORATORIES (US) |