UA75625C2 - Condensed purine derivatives as a1 adenosine receptor antagonists - Google Patents
Condensed purine derivatives as a1 adenosine receptor antagonists Download PDFInfo
- Publication number
- UA75625C2 UA75625C2 UA2003066041A UA2003066041A UA75625C2 UA 75625 C2 UA75625 C2 UA 75625C2 UA 2003066041 A UA2003066041 A UA 2003066041A UA 2003066041 A UA2003066041 A UA 2003066041A UA 75625 C2 UA75625 C2 UA 75625C2
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- alkyl
- compound
- substituted
- amino
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25065800P | 2000-12-01 | 2000-12-01 | |
| PCT/US2001/044991 WO2002044182A1 (en) | 2000-12-01 | 2001-11-30 | Condensed purine derivatives as a1 adenosine receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA75625C2 true UA75625C2 (en) | 2006-05-15 |
Family
ID=22948640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2003066041A UA75625C2 (en) | 2000-12-01 | 2001-11-30 | Condensed purine derivatives as a1 adenosine receptor antagonists |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US6605601B2 (de) |
| EP (1) | EP1347981B1 (de) |
| JP (2) | JP2004514723A (de) |
| KR (1) | KR20040011439A (de) |
| CN (1) | CN100497340C (de) |
| AR (1) | AR035400A1 (de) |
| AT (1) | ATE394402T1 (de) |
| AU (2) | AU1997702A (de) |
| BG (1) | BG107849A (de) |
| BR (1) | BR0115833A (de) |
| CA (1) | CA2430508C (de) |
| CZ (1) | CZ20031513A3 (de) |
| DE (1) | DE60133931D1 (de) |
| EA (1) | EA009814B1 (de) |
| EE (1) | EE200300260A (de) |
| ES (1) | ES2305139T3 (de) |
| GE (1) | GEP20094697B (de) |
| HK (1) | HK1059927A1 (de) |
| HU (1) | HUP0400530A3 (de) |
| IL (1) | IL156046A0 (de) |
| IS (1) | IS6821A (de) |
| MX (1) | MXPA03004857A (de) |
| MY (1) | MY127120A (de) |
| NO (1) | NO20032483L (de) |
| NZ (1) | NZ526511A (de) |
| PL (1) | PL362642A1 (de) |
| SK (1) | SK6552003A3 (de) |
| TR (1) | TR200300766T2 (de) |
| TW (1) | TWI293301B (de) |
| UA (1) | UA75625C2 (de) |
| WO (1) | WO2002044182A1 (de) |
| YU (1) | YU42903A (de) |
| ZA (2) | ZA200304067B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60018216T2 (de) * | 1999-12-24 | 2006-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Kondensierte purinderivate |
| EA009814B1 (ru) * | 2000-12-01 | 2008-04-28 | Байоджен Айдек Ма Инк. | Конденсированные производные пурина как антагонисты рецепторов аденозина а |
| EP1601649A4 (de) * | 2003-02-19 | 2009-03-04 | Endacea Inc | A1-adenosinrezeptorantagonisten |
| US20040229901A1 (en) * | 2003-02-24 | 2004-11-18 | Lauren Otsuki | Method of treatment of disease using an adenosine A1 receptor antagonist |
| JPWO2004096812A1 (ja) * | 2003-04-25 | 2006-07-13 | 協和醗酵工業株式会社 | 縮合ピリミジン誘導体 |
| RU2367442C2 (ru) * | 2003-04-25 | 2009-09-20 | Новокардия, Инк. | Способ нормализации мочеиспускания при нарушении функции почек |
| CA2528385C (en) * | 2003-06-06 | 2011-03-15 | Endacea, Inc. | A1 adenosine receptor antogonists |
| US20080161327A1 (en) * | 2005-03-11 | 2008-07-03 | Aderis Pharmaceuticals, Inc. | Substituted 9-Alkyladenines and the Use Thereof |
| US7795427B2 (en) * | 2006-02-14 | 2010-09-14 | New York University | Methods for inhibiting osteoclast differentiation, formation, or function and for increasing bone mass |
| CN101420958A (zh) * | 2006-04-06 | 2009-04-29 | 挪瓦卡尔迪阿公司 | 共投与腺苷a1受体拮抗剂和抗惊厥药 |
| EP2018380B1 (de) | 2006-05-19 | 2011-10-19 | Abbott Laboratories | CNS-aktivierte kondensierte bi- und heterocyclisch substituierte azabicyklische Alkanderivate |
| JP2009540003A (ja) * | 2006-06-16 | 2009-11-19 | ノヴァカーディア，インク． | Ａａ１ｒａの低頻度投与を含む腎機能の長期間にわたる改善 |
| BRPI0713619A2 (pt) | 2006-06-23 | 2013-01-15 | Incyte Corp | composto ou prà-droga ou sal farmaceuticamente aceitÁvel do mesmo, composiÇço, e, uso do composto. |
| WO2007150026A2 (en) | 2006-06-23 | 2007-12-27 | Incyte Corporation | Purinone derivatives as hm74a agonists |
| WO2008121882A1 (en) * | 2007-03-29 | 2008-10-09 | Novacardia, Inc. | Improved methods of administration of adenosine a1 receptor antagonists |
| US20090197900A1 (en) * | 2007-03-29 | 2009-08-06 | Howard Dittrich | Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist |
| WO2011063268A2 (en) * | 2009-11-19 | 2011-05-26 | Biogen Idec Ma Inc | Novel synthetic methods |
| US20130109645A1 (en) | 2010-03-31 | 2013-05-02 | The united States of America,as represented by Secretary,Dept.,of Health and Human Services | Adenosine receptor agonists for the treatment and prevention of vascular or joint capsule calcification disorders |
| CN111770926B (zh) * | 2018-01-04 | 2023-07-21 | 因佩蒂斯生物科学有限公司 | 三环化合物、组合物及其医药应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06102662B2 (ja) | 1989-09-01 | 1994-12-14 | 協和醗酵工業株式会社 | キサンチン誘導体 |
| DE69033614T2 (de) * | 1989-10-20 | 2001-04-19 | Kyowa Hakko Kogyo Kk | Kondensierte Purinderivate |
| SG52496A1 (en) | 1991-09-23 | 1998-09-28 | Univ Florida State | Preparation of substituted isoserine esters using metal alkoxides and beta-lactams |
| AU4471297A (en) * | 1996-10-07 | 1998-05-05 | Kyowa Hakko Kogyo Co. Ltd. | Fused purine derivatives |
| AU740770B2 (en) * | 1997-06-18 | 2001-11-15 | Aderis Pharmaceuticals, Inc. | Compositions and methods for preventing restenosis following revascularization procedures |
| ES2284256T3 (es) * | 1998-07-02 | 2007-11-01 | Kyowa Hakko Kogyo Co., Ltd. | Medicamentos para la diabetes. |
| DE60018216T2 (de) * | 1999-12-24 | 2006-02-16 | Kyowa Hakko Kogyo Co., Ltd. | Kondensierte purinderivate |
| EA009814B1 (ru) * | 2000-12-01 | 2008-04-28 | Байоджен Айдек Ма Инк. | Конденсированные производные пурина как антагонисты рецепторов аденозина а |
-
2001
- 2001-11-30 EA EA200300629A patent/EA009814B1/ru not_active IP Right Cessation
- 2001-11-30 CZ CZ20031513A patent/CZ20031513A3/cs unknown
- 2001-11-30 US US09/997,740 patent/US6605601B2/en not_active Expired - Fee Related
- 2001-11-30 SK SK655-2003A patent/SK6552003A3/sk not_active Application Discontinuation
- 2001-11-30 EE EEP200300260A patent/EE200300260A/xx unknown
- 2001-11-30 UA UA2003066041A patent/UA75625C2/uk unknown
- 2001-11-30 TR TR2003/00766T patent/TR200300766T2/xx unknown
- 2001-11-30 WO PCT/US2001/044991 patent/WO2002044182A1/en active IP Right Grant
- 2001-11-30 MX MXPA03004857A patent/MXPA03004857A/es active IP Right Grant
- 2001-11-30 ES ES01998550T patent/ES2305139T3/es not_active Expired - Lifetime
- 2001-11-30 CN CNB018208711A patent/CN100497340C/zh not_active Expired - Fee Related
- 2001-11-30 TW TW090129678A patent/TWI293301B/zh active
- 2001-11-30 NZ NZ526511A patent/NZ526511A/en unknown
- 2001-11-30 AU AU1997702A patent/AU1997702A/xx active Pending
- 2001-11-30 KR KR10-2003-7007322A patent/KR20040011439A/ko active IP Right Grant
- 2001-11-30 AT AT01998550T patent/ATE394402T1/de not_active IP Right Cessation
- 2001-11-30 AU AU2002219977A patent/AU2002219977B2/en not_active Ceased
- 2001-11-30 PL PL01362642A patent/PL362642A1/xx not_active Application Discontinuation
- 2001-11-30 GE GEAP20017016A patent/GEP20094697B/en unknown
- 2001-11-30 AR ARP010105594A patent/AR035400A1/es unknown
- 2001-11-30 CA CA2430508A patent/CA2430508C/en not_active Expired - Fee Related
- 2001-11-30 IL IL15604601A patent/IL156046A0/xx unknown
- 2001-11-30 HU HU0400530A patent/HUP0400530A3/hu unknown
- 2001-11-30 JP JP2002546552A patent/JP2004514723A/ja active Pending
- 2001-11-30 DE DE60133931T patent/DE60133931D1/de not_active Expired - Lifetime
- 2001-11-30 YU YU42903A patent/YU42903A/sh unknown
- 2001-11-30 EP EP01998550A patent/EP1347981B1/de not_active Expired - Lifetime
- 2001-11-30 MY MYPI20015481A patent/MY127120A/en unknown
- 2001-11-30 BR BR0115833-3A patent/BR0115833A/pt not_active Application Discontinuation
-
2003
- 2003-05-20 IS IS6821A patent/IS6821A/is unknown
- 2003-05-26 ZA ZA200304067A patent/ZA200304067B/en unknown
- 2003-05-27 US US10/446,573 patent/US7022686B2/en not_active Expired - Fee Related
- 2003-05-27 BG BG107849A patent/BG107849A/bg unknown
- 2003-06-02 NO NO20032483A patent/NO20032483L/no not_active Application Discontinuation
-
2004
- 2004-02-27 HK HK04101469.6A patent/HK1059927A1/xx not_active IP Right Cessation
- 2004-10-28 ZA ZA200408755A patent/ZA200408755B/xx unknown
-
2009
- 2009-12-07 JP JP2009278047A patent/JP2010053148A/ja not_active Withdrawn
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