TWI349554B - Method for producing three-dimensional structures of cells - Google Patents

Method for producing three-dimensional structures of cells

Info

Publication number
TWI349554B
TWI349554B TW097111661A TW97111661A TWI349554B TW I349554 B TWI349554 B TW I349554B TW 097111661 A TW097111661 A TW 097111661A TW 97111661 A TW97111661 A TW 97111661A TW I349554 B TWI349554 B TW I349554B
Authority
TW
Taiwan
Prior art keywords
cells
producing
dimensional structures
dimensional
structures
Prior art date
Application number
TW097111661A
Other languages
English (en)
Other versions
TW200848512A (en
Inventor
Toshinobu Koga
Soichi Nagasato
Yukihide Iwamoto
Koichi Nakayama
Original Assignee
Univ Kyushu Nat Univ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kyushu Nat Univ Corp filed Critical Univ Kyushu Nat Univ Corp
Publication of TW200848512A publication Critical patent/TW200848512A/zh
Application granted granted Critical
Publication of TWI349554B publication Critical patent/TWI349554B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/08—Flask, bottle or test tube
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0062—General methods for three-dimensional culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Clinical Laboratory Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
TW097111661A 2007-03-30 2008-03-31 Method for producing three-dimensional structures of cells TWI349554B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007094313 2007-03-30

Publications (2)

Publication Number Publication Date
TW200848512A TW200848512A (en) 2008-12-16
TWI349554B true TWI349554B (en) 2011-10-01

Family

ID=39831068

Family Applications (1)

Application Number Title Priority Date Filing Date
TW097111661A TWI349554B (en) 2007-03-30 2008-03-31 Method for producing three-dimensional structures of cells

Country Status (7)

Country Link
US (1) US8198086B2 (zh)
EP (1) EP2130910B1 (zh)
JP (1) JP4517125B2 (zh)
KR (2) KR101532446B1 (zh)
CN (1) CN101679947B (zh)
TW (1) TWI349554B (zh)
WO (1) WO2008123614A1 (zh)

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US9982238B2 (en) 2011-02-09 2018-05-29 Organ Technologies, Inc. Method for producing regenerative organ primordium provided with guide for transplantation, composition containing regenerative organ primordium provided with guide for transplantation produced thereby, and method for transplanting regenerative organ primordium provided with guide for transplantation
JP5896104B2 (ja) * 2011-06-24 2016-03-30 国立大学法人佐賀大学 細胞の立体構造体製造装置
JP5990298B2 (ja) * 2011-08-31 2016-09-14 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
JP5876787B2 (ja) * 2011-08-31 2016-03-02 富士フイルム株式会社 細胞移植用細胞構造体および細胞移植用細胞集合体
CN103946367A (zh) * 2011-11-18 2014-07-23 国立大学法人佐贺大学 用于制作细胞的立体构造体制作用的支承体的装置
US20160022870A1 (en) * 2013-03-15 2016-01-28 Cyfuse Biomedical K.K. Cardiac or vascular tissue spheroid
JP2016105700A (ja) * 2013-03-19 2016-06-16 国立大学法人九州大学 肝臓組織型スフェロイド
US9771554B2 (en) * 2013-07-16 2017-09-26 Brown University Device and method for engineering living tissues
JP2015213451A (ja) * 2014-05-08 2015-12-03 大日本印刷株式会社 メッシュプレート付針状治具
WO2016046938A1 (ja) * 2014-09-25 2016-03-31 株式会社サイフューズ 細胞トレイ、並びに細胞構造体製造装置、方法、及びシステム
WO2016108758A1 (en) * 2014-12-30 2016-07-07 Agency For Science, Technology And Research Technique for formation and assembly of 3d cellular structures
JP6534269B2 (ja) * 2015-03-18 2019-06-26 富士フイルム株式会社 管状構造物、細胞構造体の製造方法、及び管状構造物の製造方法
JP6880384B2 (ja) * 2015-09-30 2021-06-02 澁谷工業株式会社 細胞塊シート製造装置
EP3150696A1 (en) 2015-09-30 2017-04-05 Shibuya Corporation Apparatus for producing cell mass sheet and method for producing cell mass sheet
JP6660544B2 (ja) * 2015-09-30 2020-03-11 澁谷工業株式会社 細胞塊シート培養装置
JP2017063732A (ja) * 2015-09-30 2017-04-06 澁谷工業株式会社 細胞塊培養装置
JP6593589B2 (ja) * 2015-09-30 2019-10-23 澁谷工業株式会社 細胞塊シートの作製方法および細胞塊シート
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EP3162890A1 (en) 2015-10-29 2017-05-03 Shibuya Corporation Method and apparatus for producing cell mass structure
JP6882658B2 (ja) * 2015-10-29 2021-06-02 澁谷工業株式会社 細胞の集合構造体の作製方法および作製装置
WO2017134787A1 (ja) * 2016-02-04 2017-08-10 株式会社サイフューズ 細胞トレイ、並びに細胞構造体製造装置、方法、及びシステム
JP6822769B2 (ja) 2016-02-29 2021-01-27 米満　吉和 規則的に配置された同一サイズのスフェロイド及びその利用
WO2017203780A1 (ja) * 2016-05-27 2017-11-30 株式会社 日立ハイテクノロジーズ 細胞の立体構造体の作製装置及び作製方法
US10345208B2 (en) 2016-07-12 2019-07-09 Deka Products Limited Partnership System and method for applying force to a device
US11254901B2 (en) 2016-07-12 2022-02-22 Deka Products Limited Partnership System and method for printing tissue
EP3498822B1 (en) 2016-08-10 2021-11-10 Cyberdyne Inc. Method for producing three-dimensional structure of cells and system for producing three-dimensional structure
WO2018051415A1 (ja) * 2016-09-13 2018-03-22 次郎 大野 ３次元細胞構造体の製造方法およびそれに用いる支持体
JP2019213457A (ja) * 2016-10-12 2019-12-19 Ａｇｃ株式会社 培養細胞構造体の製造方法
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
JP6889363B2 (ja) * 2016-12-05 2021-06-18 澁谷工業株式会社 細胞の集合構造体の作製方法および作製装置
WO2018110053A1 (ja) * 2016-12-13 2018-06-21 株式会社サイフューズ 細胞構造体製造装置および細胞トレイ
WO2018216228A1 (ja) * 2017-05-26 2018-11-29 株式会社サイフューズ 立体型細胞構造体を用いた尿路組織の再生方法
US10570362B2 (en) 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
WO2019073522A1 (ja) * 2017-10-10 2019-04-18 株式会社サイフューズ 細胞トレイおよび不織布組立部材
JP7037038B2 (ja) * 2017-10-17 2022-03-16 澁谷工業株式会社 細胞の集合構造体の作製装置
EP3705568A4 (en) 2017-10-30 2021-08-11 Public University Corporation Yokohama City University CONSTRUCT WITH CONNECTED STRUCTURE AND CELL MASS
JP6334837B1 (ja) * 2017-10-30 2018-05-30 株式会社サイフューズ 細胞構造体製造装置
CN111315864A (zh) * 2018-03-19 2020-06-19 细胞网络株式会社 细胞结构体的制造装置、制造系统以及制造方法
US20200399613A1 (en) * 2018-03-28 2020-12-24 Public University Corporation Yokohama City University Cell Mass Fusion Method
EP3778850A4 (en) 2018-04-09 2021-04-21 Cyfuse Biomedical K.K. CONNECTION PROCEDURE FOR CELLULAR STRUCTURES AND AUXILIARY CONNECTION
JP7148998B2 (ja) 2018-04-09 2022-10-06 株式会社サイフューズ 管状細胞構造体培養維持装置および管状細胞構造体維持補助具
JP7151218B2 (ja) 2018-07-04 2022-10-12 横河電機株式会社 細胞構築物の製造方法、担体、および担体の製造方法
US20210324319A1 (en) * 2019-02-01 2021-10-21 Cyfuse Biomedical K.K. Cell structure manufacturing system
WO2020157981A1 (ja) * 2019-02-01 2020-08-06 株式会社サイフューズ 細胞構造体固定抜去システム
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US20220154123A1 (en) * 2019-03-15 2022-05-19 Saga University Method for manufacturing luminal structure
US20220331483A1 (en) * 2019-05-16 2022-10-20 Cyfuse Biomedical K.K. Nerve regeneration inducing material
JP7452792B2 (ja) * 2019-09-06 2024-03-19 国立大学法人 長崎大学 気管支断端瘻治療用細胞構造体とその製造方法
KR102636511B1 (ko) * 2020-03-20 2024-02-14 주식회사 에이엔케이 기판 상에 형성된 모낭 세포 스페로이드 및 이의 제조방법
KR102636512B1 (ko) * 2020-03-20 2024-02-14 주식회사 에이엔케이 모유두 세포의 반복 시딩 및 배양을 통한 모유두 스페로이드의 제조방법
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Also Published As

Publication number Publication date
EP2130910A4 (en) 2011-08-24
TW200848512A (en) 2008-12-16
CN101679947B (zh) 2013-03-06
CN101679947A (zh) 2010-03-24
WO2008123614A1 (ja) 2008-10-16
EP2130910B1 (en) 2016-10-19
KR101532446B1 (ko) 2015-06-29
KR20150036810A (ko) 2015-04-07
JPWO2008123614A1 (ja) 2010-07-15
JP4517125B2 (ja) 2010-08-04
EP2130910A1 (en) 2009-12-09
KR20100014544A (ko) 2010-02-10
US20110200559A1 (en) 2011-08-18
US8198086B2 (en) 2012-06-12

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