TR200002058T2 - Antiviraller - Google Patents
AntivirallerInfo
- Publication number
- TR200002058T2 TR200002058T2 TR2000/02058T TR200002058T TR200002058T2 TR 200002058 T2 TR200002058 T2 TR 200002058T2 TR 2000/02058 T TR2000/02058 T TR 2000/02058T TR 200002058 T TR200002058 T TR 200002058T TR 200002058 T2 TR200002058 T2 TR 200002058T2
- Authority
- TR
- Turkey
- Prior art keywords
- antivirals
- antirertrovirals
- halo
- bromo
- cyano
- Prior art date
Links
- 239000003443 antiviral agent Substances 0.000 title 1
- 229940121357 antivirals Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Antirertroviraller olarak aktiviteye sahip olan bir formül (I) bilesigi: ki burada Rx siyano veya bromodur; R1 halodur;R2C1-C3 alkil; ve bunun farmasötik olarak kabul edilen tuzlari ve yan-ilaçlaridir.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9800116A SE9800116D0 (sv) | 1998-01-16 | 1998-01-16 | Antivirals I |
| SE9800113A SE9800113D0 (sv) | 1998-01-16 | 1998-01-16 | Antivirals II |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200002058T2 true TR200002058T2 (tr) | 2001-05-21 |
Family
ID=26663191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/02058T TR200002058T2 (tr) | 1998-01-16 | 1999-01-15 | Antiviraller |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US6486183B1 (tr) |
| EP (1) | EP1054867B1 (tr) |
| JP (1) | JP4488621B2 (tr) |
| KR (1) | KR100566445B1 (tr) |
| CN (2) | CN1158261C (tr) |
| AR (1) | AR016169A1 (tr) |
| AT (1) | ATE264305T1 (tr) |
| AU (1) | AU739766B2 (tr) |
| BR (1) | BR9906933A (tr) |
| CA (1) | CA2318694C (tr) |
| CZ (1) | CZ299387B6 (tr) |
| DE (1) | DE69916425T2 (tr) |
| DK (1) | DK1054867T3 (tr) |
| EA (1) | EA003327B1 (tr) |
| ES (1) | ES2220039T3 (tr) |
| HK (1) | HK1036280A1 (tr) |
| HU (1) | HU228886B1 (tr) |
| IL (1) | IL137196A0 (tr) |
| MY (1) | MY129292A (tr) |
| NZ (1) | NZ505543A (tr) |
| PL (1) | PL191832B1 (tr) |
| PT (1) | PT1054867E (tr) |
| SK (1) | SK285779B6 (tr) |
| TR (1) | TR200002058T2 (tr) |
| TW (1) | TW470645B (tr) |
| WO (1) | WO1999036406A1 (tr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999036406A1 (en) * | 1998-01-16 | 1999-07-22 | Medivir Ab | Antivirals |
| WO1999051613A1 (en) * | 1998-04-03 | 1999-10-14 | Medivir Ab | Prodrugs of phosphorous-containing pharmaceuticals |
| SE0100733D0 (sv) | 2001-03-05 | 2001-03-05 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
| SE0102867D0 (sv) * | 2001-08-28 | 2001-08-28 | Medivir Ab | Non-nucleoside reverse transcriptase inhibitors |
| SG149070A1 (en) * | 2004-01-08 | 2009-01-29 | Medivir Ab | Non-nucleotide reverse transcriptase inhibitors |
| BRPI0617074A2 (pt) * | 2005-08-31 | 2011-07-12 | Cipla Ltd | composição farmacêutica, uso de lamivudina, nevirapina e stavudina, uso de stavudina, lamivudina e nevirapina, método para tratar uma infecção viral em um humano, método para preparar uma composição farmacêutica, método para preparar uma forma de dosagem unitária farmacêutica bicamadas e método para preparar uma forma de dosagem unitária farmacêutica tri-camadas |
| US7302330B1 (en) * | 2006-09-01 | 2007-11-27 | Gm Global Technology Operations, Inc. | Torque converter clutch dynamic control |
| GB0623258D0 (en) | 2006-11-22 | 2007-01-03 | Remynd Nv | Thiadiazole derivatives for the treatment of neuro-degenerative diseases |
| LT2598482T (lt) * | 2010-07-29 | 2018-07-10 | Oryzon Genomics, S.A. | Demetilazės lsd1 inhibitoriai arilciklopropilamino pagrindu ir jų medicininis panaudojimas |
| IN2014MN01907A (tr) | 2012-03-05 | 2015-07-10 | Cipla Ltd |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69414708T2 (de) * | 1993-08-24 | 1999-04-15 | Medivir Ab | Verbindungen und methoden zur inhibition von hiv und verwandten viren |
| US5849769A (en) * | 1994-08-24 | 1998-12-15 | Medivir Ab | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection |
| WO1999036406A1 (en) * | 1998-01-16 | 1999-07-22 | Medivir Ab | Antivirals |
-
1999
- 1999-01-15 WO PCT/SE1999/000053 patent/WO1999036406A1/en active IP Right Grant
- 1999-01-15 AU AU24450/99A patent/AU739766B2/en not_active Ceased
- 1999-01-15 CA CA002318694A patent/CA2318694C/en not_active Expired - Fee Related
- 1999-01-15 PT PT99903983T patent/PT1054867E/pt unknown
- 1999-01-15 SK SK1033-2000A patent/SK285779B6/sk not_active IP Right Cessation
- 1999-01-15 CN CNB99803908XA patent/CN1158261C/zh not_active Expired - Fee Related
- 1999-01-15 DK DK99903983T patent/DK1054867T3/da active
- 1999-01-15 CZ CZ20002604A patent/CZ299387B6/cs not_active IP Right Cessation
- 1999-01-15 US US09/600,309 patent/US6486183B1/en not_active Expired - Fee Related
- 1999-01-15 MY MYPI99000158A patent/MY129292A/en unknown
- 1999-01-15 NZ NZ505543A patent/NZ505543A/xx not_active IP Right Cessation
- 1999-01-15 EP EP99903983A patent/EP1054867B1/en not_active Expired - Lifetime
- 1999-01-15 EA EA200000770A patent/EA003327B1/ru not_active IP Right Cessation
- 1999-01-15 HU HU0100432A patent/HU228886B1/hu not_active IP Right Cessation
- 1999-01-15 BR BR9906933-4A patent/BR9906933A/pt not_active IP Right Cessation
- 1999-01-15 JP JP2000540122A patent/JP4488621B2/ja not_active Expired - Fee Related
- 1999-01-15 CN CNA03127224XA patent/CN1522698A/zh active Pending
- 1999-01-15 KR KR1020007007830A patent/KR100566445B1/ko not_active IP Right Cessation
- 1999-01-15 TR TR2000/02058T patent/TR200002058T2/tr unknown
- 1999-01-15 AR ARP990100146A patent/AR016169A1/es active IP Right Grant
- 1999-01-15 IL IL13719699A patent/IL137196A0/xx not_active IP Right Cessation
- 1999-01-15 AT AT99903983T patent/ATE264305T1/de active
- 1999-01-15 ES ES99903983T patent/ES2220039T3/es not_active Expired - Lifetime
- 1999-01-15 DE DE69916425T patent/DE69916425T2/de not_active Expired - Lifetime
- 1999-01-15 PL PL341819A patent/PL191832B1/pl not_active IP Right Cessation
- 1999-01-15 TW TW088100605A patent/TW470645B/zh not_active IP Right Cessation
-
2001
- 2001-10-11 HK HK01107142A patent/HK1036280A1/xx not_active IP Right Cessation
-
2002
- 2002-09-12 US US10/243,118 patent/US7148243B2/en not_active Expired - Fee Related
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