DK1054867T3 - Antivirale midler - Google Patents

Antivirale midler

Info

Publication number
DK1054867T3
DK1054867T3 DK99903983T DK99903983T DK1054867T3 DK 1054867 T3 DK1054867 T3 DK 1054867T3 DK 99903983 T DK99903983 T DK 99903983T DK 99903983 T DK99903983 T DK 99903983T DK 1054867 T3 DK1054867 T3 DK 1054867T3
Authority
DK
Denmark
Prior art keywords
antiviral agents
antiviral
agents
Prior art date
Application number
DK99903983T
Other languages
Danish (da)
English (en)
Inventor
Christer Sahlberg
Per Engelhardt
Rolf Noreen
Marita Hoegberg
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9800116A external-priority patent/SE9800116D0/xx
Priority claimed from SE9800113A external-priority patent/SE9800113D0/xx
Application filed by Medivir Ab filed Critical Medivir Ab
Application granted granted Critical
Publication of DK1054867T3 publication Critical patent/DK1054867T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61Halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99903983T 1998-01-16 1999-01-15 Antivirale midler DK1054867T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9800116A SE9800116D0 (sv) 1998-01-16 1998-01-16 Antivirals I
SE9800113A SE9800113D0 (sv) 1998-01-16 1998-01-16 Antivirals II
PCT/SE1999/000053 WO1999036406A1 (en) 1998-01-16 1999-01-15 Antivirals

Publications (1)

Publication Number Publication Date
DK1054867T3 true DK1054867T3 (da) 2004-08-09

Family

ID=26663191

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99903983T DK1054867T3 (da) 1998-01-16 1999-01-15 Antivirale midler

Country Status (26)

Country Link
US (2) US6486183B1 (tr)
EP (1) EP1054867B1 (tr)
JP (1) JP4488621B2 (tr)
KR (1) KR100566445B1 (tr)
CN (2) CN1522698A (tr)
AR (1) AR016169A1 (tr)
AT (1) ATE264305T1 (tr)
AU (1) AU739766B2 (tr)
BR (1) BR9906933A (tr)
CA (1) CA2318694C (tr)
CZ (1) CZ299387B6 (tr)
DE (1) DE69916425T2 (tr)
DK (1) DK1054867T3 (tr)
EA (1) EA003327B1 (tr)
ES (1) ES2220039T3 (tr)
HK (1) HK1036280A1 (tr)
HU (1) HU228886B1 (tr)
IL (1) IL137196A0 (tr)
MY (1) MY129292A (tr)
NZ (1) NZ505543A (tr)
PL (1) PL191832B1 (tr)
PT (1) PT1054867E (tr)
SK (1) SK285779B6 (tr)
TR (1) TR200002058T2 (tr)
TW (1) TW470645B (tr)
WO (1) WO1999036406A1 (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9906933A (pt) * 1998-01-16 2001-11-27 Medivir Ab Antiviróticos
WO1999051613A1 (en) * 1998-04-03 1999-10-14 Medivir Ab Prodrugs of phosphorous-containing pharmaceuticals
SE0100733D0 (sv) 2001-03-05 2001-03-05 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
SE0102867D0 (sv) 2001-08-28 2001-08-28 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
EP1701942B1 (en) * 2004-01-08 2009-12-09 Medivir AB Non-nucleotide reverse transcriptase inhibitors
WO2007026156A1 (en) * 2005-08-31 2007-03-08 Cipla Limited Pharmaceutical combinations containing lamivudine, stavudine and nevirapine
US7302330B1 (en) * 2006-09-01 2007-11-27 Gm Global Technology Operations, Inc. Torque converter clutch dynamic control
GB0623258D0 (en) 2006-11-22 2007-01-03 Remynd Nv Thiadiazole derivatives for the treatment of neuro-degenerative diseases
RS57331B1 (sr) * 2010-07-29 2018-08-31 Oryzon Genomics Sa Inhibitori demetilaze za lsd1 zasnovani na arilciklopropilaminu i njihova medicinska upotreba
CA2866133A1 (en) 2012-03-05 2013-09-12 Cipla Limited Pharmaceutical antiretroviral combinations comprising lamivudine, festinavir and nevirapine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0706514T3 (da) * 1993-08-24 1999-08-02 Medivir Ab Forbindelser og fremgangsmåder til inhibering af HIV og relaterede vira
US5849769A (en) * 1994-08-24 1998-12-15 Medivir Ab N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection
BR9906933A (pt) * 1998-01-16 2001-11-27 Medivir Ab Antiviróticos

Also Published As

Publication number Publication date
EA200000770A1 (ru) 2000-12-25
ES2220039T3 (es) 2004-12-01
SK10332000A3 (sk) 2002-04-04
CN1522698A (zh) 2004-08-25
ATE264305T1 (de) 2004-04-15
PT1054867E (pt) 2004-09-30
KR100566445B1 (ko) 2006-03-31
DE69916425T2 (de) 2005-05-19
AU739766B2 (en) 2001-10-18
AU2445099A (en) 1999-08-02
EP1054867B1 (en) 2004-04-14
JP4488621B2 (ja) 2010-06-23
BR9906933A (pt) 2001-11-27
TW470645B (en) 2002-01-01
WO1999036406A1 (en) 1999-07-22
PL341819A1 (en) 2001-05-07
KR20010034194A (ko) 2001-04-25
US6486183B1 (en) 2002-11-26
MY129292A (en) 2007-03-30
CZ20002604A3 (en) 2001-05-16
EP1054867A1 (en) 2000-11-29
DE69916425D1 (de) 2004-05-19
CN1158261C (zh) 2004-07-21
TR200002058T2 (tr) 2001-05-21
US7148243B2 (en) 2006-12-12
HUP0100432A2 (hu) 2001-07-30
NZ505543A (en) 2002-09-27
IL137196A0 (en) 2001-07-24
HK1036280A1 (en) 2001-12-28
JP2002509137A (ja) 2002-03-26
SK285779B6 (sk) 2007-08-02
HU228886B1 (en) 2013-06-28
CN1292781A (zh) 2001-04-25
US20030119881A1 (en) 2003-06-26
CA2318694A1 (en) 1999-07-22
AR016169A1 (es) 2001-06-20
CZ299387B6 (cs) 2008-07-09
PL191832B1 (pl) 2006-07-31
HUP0100432A3 (en) 2002-12-28
CA2318694C (en) 2009-10-27
EA003327B1 (ru) 2003-04-24

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