JP4080541B2
(ja)
*
|
1996-10-18 |
2008-04-23 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
セリンプロテアーゼ、特にc型肝炎ウイルスns3プロテアーゼの阻害因子
|
WO1998024785A1
(en)
*
|
1996-12-02 |
1998-06-11 |
Fujisawa Pharmaceutical Co., Ltd. |
Indole-urea derivatives with 5-ht antagonist properties
|
EP1366766A1
(en)
*
|
1997-03-14 |
2003-12-03 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of IMPDH enzyme
|
US6093742A
(en)
*
|
1997-06-27 |
2000-07-25 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of p38
|
EP1027328B1
(en)
*
|
1997-10-31 |
2006-08-23 |
Aventis Pharma Limited |
Substituted anilides
|
US7329670B1
(en)
|
1997-12-22 |
2008-02-12 |
Bayer Pharmaceuticals Corporation |
Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas
|
ATE300299T1
(de)
*
|
1997-12-22 |
2005-08-15 |
Bayer Pharmaceuticals Corp |
Inhibierung der raf-kinase durch substituierte heterocyclische harnstoffverbindungen
|
ATE346600T1
(de)
*
|
1997-12-22 |
2006-12-15 |
Bayer Pharmaceuticals Corp |
Inhibierung der p38 kinase-aktivität durch die verwendung von aryl- und heteroarylsubstituierten harnstoffen
|
US7517880B2
(en)
|
1997-12-22 |
2009-04-14 |
Bayer Pharmaceuticals Corporation |
Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
|
WO1999055663A1
(en)
*
|
1998-04-29 |
1999-11-04 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of impdh enzyme
|
WO1999062869A1
(fr)
*
|
1998-06-04 |
1999-12-09 |
Kumiai Chemical Industry Co., Ltd. |
Derives de phenylacetylene et bactericides a usage agricole ou horticole
|
CN1263733C
(zh)
*
|
1998-10-22 |
2006-07-12 |
神经研究公司 |
取代苯基衍生物,它们的制备和用途
|
AU1707700A
(en)
|
1998-10-29 |
2000-05-22 |
Bristol-Myers Squibb Company |
Novel inhibitors of impdh enzyme
|
US6596747B2
(en)
|
1998-10-29 |
2003-07-22 |
Bristol-Myers Squibb Company |
Compounds derived from an amine nucleus and pharmaceutical compositions comprising same
|
US6420403B1
(en)
|
1998-10-29 |
2002-07-16 |
Edwin J. Iwanowicz |
Inhibitors of IMPDH enzyme
|
AU764479B2
(en)
|
1998-10-29 |
2003-08-21 |
Bristol-Myers Squibb Company |
Compounds derived from an amine nucleus that are inhibitors of IMPDH enzyme
|
GB9823873D0
(en)
|
1998-10-30 |
1998-12-30 |
Pharmacia & Upjohn Spa |
2-ureido-thiazole derivatives,process for their preparation,and their use as antitumour agents
|
RU2233269C2
(ru)
*
|
1998-11-02 |
2004-07-27 |
Авентис Фарма Лимитед |
Замещенные анилиды, фармацевтическая композиция и способ лечения
|
US6262090B1
(en)
|
1998-12-09 |
2001-07-17 |
American Home Products Corporation |
Aminopyridine-containing thiourea inhibitors of herpes viruses
|
ATE267824T1
(de)
*
|
1998-12-09 |
2004-06-15 |
Wyeth Corp |
Alpha-methylbenzyl-enthaltende thioharnstoffe als inhibitoren von herpes-viren mit einer phenylenediamingruppe
|
US6166028A
(en)
|
1998-12-09 |
2000-12-26 |
American Home Products Corporation |
Diaminopuridine-containing thiourea inhibitors of herpes viruses
|
US6201013B1
(en)
|
1998-12-09 |
2001-03-13 |
American Home Products Corporation |
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing a substituted phenylenediamine group
|
IL143262A0
(en)
*
|
1998-12-09 |
2002-04-21 |
American Home Prod |
Thiourea inhibitors of herpes viruses
|
US6337338B1
(en)
|
1998-12-15 |
2002-01-08 |
Telik, Inc. |
Heteroaryl-aryl ureas as IGF-1 receptor antagonists
|
WO2000037434A1
(fr)
*
|
1998-12-22 |
2000-06-29 |
Mitsubishi Chemical Corporation |
Derives d'amide
|
RU2319693C9
(ru)
|
1999-01-13 |
2008-08-20 |
Байер Копэрейшн |
Производные мочевины (варианты), фармацевтическая композиция (варианты) и способ лечения заболевания, связанного с ростом раковых клеток (варианты)
|
ATE556713T1
(de)
|
1999-01-13 |
2012-05-15 |
Bayer Healthcare Llc |
Omega-carboxyarylsubstituierte-diphenyl- harnstoffe als p38-kinasehemmer
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
US7928239B2
(en)
|
1999-01-13 |
2011-04-19 |
Bayer Healthcare Llc |
Inhibition of RAF kinase using quinolyl, isoquinolyl or pyridyl ureas
|
EP1140840B1
(en)
|
1999-01-13 |
2006-03-22 |
Bayer Pharmaceuticals Corp. |
-g(v)-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
SK12832001A3
(sk)
*
|
1999-03-12 |
2002-01-07 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Protizápalové látky, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
|
CN1196687C
(zh)
|
1999-03-19 |
2005-04-13 |
沃泰克斯药物股份有限公司 |
Impdh酶抑制剂
|
US6653309B1
(en)
|
1999-04-26 |
2003-11-25 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of IMPDH enzyme technical field of the invention
|
WO2000073288A1
(en)
*
|
1999-05-28 |
2000-12-07 |
Vertex Pharmaceuticals Incorporated |
Method for preparing 5-substituted oxazoles
|
US6107052A
(en)
*
|
1999-06-09 |
2000-08-22 |
Roche Diagnostics Corporation |
Enzymatic measurement of mycophenolic acid
|
WO2001000622A1
(en)
*
|
1999-06-25 |
2001-01-04 |
Vertex Pharmaceuticals Incorporated |
Prodrugs of carbamate inhibitors of impdh
|
JP2001011059A
(ja)
*
|
1999-06-28 |
2001-01-16 |
Nippon Synthetic Chem Ind Co Ltd:The |
5−(2−置換−4−ニトロフェニル)−オキサゾールの製造方法
|
JP2001011060A
(ja)
*
|
1999-06-28 |
2001-01-16 |
Nippon Synthetic Chem Ind Co Ltd:The |
新規オキサゾール化合物及びその製造方法
|
TWI262185B
(en)
*
|
1999-10-01 |
2006-09-21 |
Eisai Co Ltd |
Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives
|
US6867299B2
(en)
|
2000-02-24 |
2005-03-15 |
Hoffmann-La Roche Inc. |
Oxamide IMPDH inhibitors
|
WO2001081340A2
(en)
*
|
2000-04-24 |
2001-11-01 |
Bristol-Myers Squibb Company |
Heterocycles that are inhibitors of impdh enzyme
|
SV2003000617A
(es)
*
|
2000-08-31 |
2003-01-13 |
Lilly Co Eli |
Inhibidores de la proteasa peptidomimetica ref. x-14912m
|
US6423849B1
(en)
|
2000-09-01 |
2002-07-23 |
The Nippon Synthetic Chemical Industry Co., Ltd. |
Process of preparing 5-(2-substituted-4-nitrophenyl)-oxazole, novel oxazole compound, and process of preparing the same
|
US7235576B1
(en)
|
2001-01-12 |
2007-06-26 |
Bayer Pharmaceuticals Corporation |
Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
US7371763B2
(en)
|
2001-04-20 |
2008-05-13 |
Bayer Pharmaceuticals Corporation |
Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
|
US6593362B2
(en)
*
|
2001-05-21 |
2003-07-15 |
Guilford Pharmaceuticals Inc. |
Non-peptidic cyclophilin binding compounds and their use
|
TW200301698A
(en)
|
2001-12-21 |
2003-07-16 |
Bristol Myers Squibb Co |
Acridone inhibitors of IMPDH enzyme
|
EP1478358B1
(en)
|
2002-02-11 |
2013-07-03 |
Bayer HealthCare LLC |
Sorafenib tosylate for the treatment of diseases characterized by abnormal angiogenesis
|
CA2475818C
(en)
|
2002-02-11 |
2011-07-19 |
Bayer Pharmaceuticals Corporation |
Aryl ureas as kinase inhibitors
|
EP1402887A1
(en)
*
|
2002-09-18 |
2004-03-31 |
Jerini AG |
New compounds for the inhibition of undesired cell proliferation and use thereof
|
JP4789621B2
(ja)
|
2002-12-06 |
2011-10-12 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
ジフェニルUraIMPDHインヒビターおよびアポトーシス誘導性抗癌剤を含む組成物
|
ATE457716T1
(de)
|
2002-12-30 |
2010-03-15 |
Angiotech Int Ag |
Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
|
US7220768B2
(en)
*
|
2003-02-11 |
2007-05-22 |
Wyeth Holdings Corp. |
Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus
|
WO2005000284A2
(en)
|
2003-05-20 |
2005-01-06 |
Bayer Pharmaceuticals Corporation |
Diaryl ureas for diseases mediated by pdgfr
|
PL1663978T3
(pl)
|
2003-07-23 |
2008-04-30 |
Bayer Healthcare Llc |
Fluoropodstawiony omega-karboksyarylodifenylomocznik do leczenia i profilaktyki chorób i stanów
|
TWI359147B
(en)
*
|
2003-09-05 |
2012-03-01 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hcv n
|
AU2004282148A1
(en)
|
2003-10-10 |
2005-04-28 |
Vertex Pharmaceuticals Incoporated |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
AR045870A1
(es)
*
|
2003-10-11 |
2005-11-16 |
Vertex Pharma |
Terapia de combinacion para la infeccion de virus de hepatitis c
|
JP4890254B2
(ja)
*
|
2003-10-27 |
2012-03-07 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Hcvns3−ns4aプロテアーゼ耐性突然変異体
|
EP1944042A1
(en)
|
2003-10-27 |
2008-07-16 |
Vertex Pharmceuticals Incorporated |
Combinations for HCV treatment
|
CN1938332B
(zh)
|
2004-02-04 |
2011-10-19 |
沃泰克斯药物股份有限公司 |
丝氨酸蛋白酶、特别是hcv ns3-ns4a蛋白酶的抑制剂
|
US7317030B2
(en)
|
2004-02-26 |
2008-01-08 |
4Sc Ag |
Compounds as inhibitors of cell proliferation and viral infections
|
EP1568696A1
(en)
*
|
2004-02-26 |
2005-08-31 |
4Sc Ag |
Compounds as inhibitors of cell proliferation and viral infections
|
EP2583678A3
(en)
|
2004-06-24 |
2013-11-13 |
Novartis Vaccines and Diagnostics, Inc. |
Small molecule immunopotentiators and assays for their detection
|
CA2576297C
(en)
|
2004-08-12 |
2011-01-25 |
Pfizer Inc. |
Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors
|
SG191661A1
(en)
*
|
2004-10-01 |
2013-07-31 |
Vertex Pharma |
Hcv ns3-ns4a protease inhibition
|
TW201424733A
(zh)
|
2004-10-29 |
2014-07-01 |
Vertex Pharma |
劑量型式
|
WO2006076592A1
(en)
*
|
2005-01-14 |
2006-07-20 |
Cgi Pharmaceuticals, Inc. |
1,3 substituted diaryl ureas as modulators of kinase activity
|
ES2393741T3
(es)
*
|
2005-01-14 |
2012-12-27 |
Gilead Connecticut, Inc. |
Ureas 1,3-diarilsustituidas como moduladores de la actividad quinasa
|
EP1917010A2
(en)
*
|
2005-02-08 |
2008-05-07 |
Aspreva Pharmaceuticals SA |
Compositions and methods for treating vascular, autoimmune and inflammatory diseases
|
WO2006086498A2
(en)
*
|
2005-02-08 |
2006-08-17 |
Aspreva Pharmaceuticals Sa |
Treatment of vascular, autoimmune and inflammatory diseases using low dosages of impdh inhibitors
|
PL1868579T3
(pl)
|
2005-03-07 |
2011-03-31 |
Bayer Healthcare Llc |
Kompozycja farmaceutyczna zawierająca difenylomocznik podstawiony omega-karboksyarylem do leczenia nowotworu
|
US7777040B2
(en)
*
|
2005-05-03 |
2010-08-17 |
Cgi Pharmaceuticals, Inc. |
Certain substituted ureas, as modulators of kinase activity
|
EP1879858A2
(en)
|
2005-05-09 |
2008-01-23 |
Vertex Pharmaceuticals, Inc. |
Processes for preparing biaryl ureas and analogs thereof
|
US7605270B2
(en)
*
|
2005-05-09 |
2009-10-20 |
Vertex Pharmaceuticals Incorporated |
Polymorphic forms of (S).-tetrahydrofuran-3-yl-3-(3-(3-methoxy-4-(oxazol-5-yl) phenyl) ureido) benzylcarbamate
|
WO2007014920A1
(en)
|
2005-07-29 |
2007-02-08 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis c virus
|
PE20070210A1
(es)
|
2005-07-29 |
2007-04-16 |
Tibotec Pharm Ltd |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
US7666834B2
(en)
|
2005-07-29 |
2010-02-23 |
Tibotec Pharmaceuticals Ltd. |
Macrocyclic inhibitors of hepatitis C virus
|
PE20070211A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Compuestos macrociclicos como inhibidores del virus de hepatitis c
|
ME01318B
(me)
|
2005-07-29 |
2013-12-20 |
Tibotec Pharm Ltd |
Makrociklički inhibitori virusa hepatitisa C
|
PL1913015T3
(pl)
|
2005-07-29 |
2014-04-30 |
Janssen R&D Ireland |
Makrocykliczne inhibitory wirusa zapalenia wątroby typu C
|
DE602006019741D1
(de)
|
2005-07-29 |
2011-03-03 |
Medivir Ab |
Makrocyclische inhibitoren des hepatitis-c-virus
|
TWI393723B
(zh)
|
2005-07-29 |
2013-04-21 |
Tibotec Pharm Ltd |
C型肝炎病毒之大環抑制劑(九)
|
JO2768B1
(en)
|
2005-07-29 |
2014-03-15 |
تيبوتيك فارماسيوتيكالز ليمتد |
Large cyclic inhibitors of hepatitis C virus
|
MX2008001528A
(es)
|
2005-08-02 |
2008-04-04 |
Vertex Pharma |
Inhibidores de serina proteasas.
|
AR055395A1
(es)
*
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
US7964624B1
(en)
*
|
2005-08-26 |
2011-06-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
EP2392588A3
(en)
|
2005-11-11 |
2012-03-07 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
US7705138B2
(en)
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
JP5436864B2
(ja)
|
2006-02-27 |
2014-03-05 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Vx−950を含む共結晶体およびそれを含む医薬組成物
|
WO2007109080A2
(en)
|
2006-03-16 |
2007-09-27 |
Vertex Pharmaceuticals Incorporated |
Deuterated hepatitis c protease inhibitors
|
BRPI0710878A2
(pt)
|
2006-04-11 |
2015-03-31 |
Novartis Ag |
Compostos orgânicos e seus usos
|
JP2010504362A
(ja)
*
|
2006-09-25 |
2010-02-12 |
アレテ セラピューティクス, インコーポレイテッド |
可溶性エポキシドヒドロラーゼ阻害剤
|
WO2008040778A2
(en)
|
2006-10-04 |
2008-04-10 |
Tibotec Pharmaceuticals Ltd. |
Carboxamide 4-[(4-pyridyl)amino] pyrimidines for the treatment of hepatitis c
|
CL2007003299A1
(es)
|
2006-11-17 |
2008-08-22 |
Tibotec Pharm Ltd |
Compuestos derivados de macrociclos, inhibidores del virus de la hepatitis c; procedimiento de preparacion; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c.
|
EP2134717A2
(en)
*
|
2007-02-27 |
2009-12-23 |
Vertex Pharmceuticals Incorporated |
Inhibitors of serine proteases
|
PT2114924E
(pt)
*
|
2007-02-27 |
2012-04-03 |
Vertex Pharma |
Co-cristais e composições farmacêuticas que compreendem os mesmos
|
JP2010524974A
(ja)
*
|
2007-04-20 |
2010-07-22 |
デシファラ ファーマスーティカルズ, エルエルシー |
骨髄増殖性疾患および他の増殖性疾患の治療に有用なキナーゼ阻害剤
|
MX2009011930A
(es)
|
2007-05-04 |
2009-11-18 |
Vertex Pharma |
Terapia de combinacion para el tratamiento de infeccion de virus de hepatitis c.
|
EP2185546B1
(en)
*
|
2007-08-30 |
2011-10-26 |
Vertex Pharmceuticals Incorporated |
Co-crystals and pharmaceutical compositions comprising the same
|
US8524716B2
(en)
|
2007-12-24 |
2013-09-03 |
Janssen R&D Ireland |
Macrocyclic indoles as hepatitis C virus inhibitors
|
TWI454476B
(zh)
|
2008-07-08 |
2014-10-01 |
Tibotec Pharm Ltd |
用作c型肝炎病毒抑制劑之巨環吲哚衍生物
|
CN102124012B
(zh)
|
2008-08-14 |
2014-07-02 |
泰博特克药品公司 |
可作为丙型肝炎病毒抑制剂的大环吲哚衍生物
|
PE20150939A1
(es)
|
2008-12-03 |
2015-07-19 |
Presidio Pharmaceuticals Inc |
Inhibidores de la proteina no estructural 5a del virus de la hepatitis c
|
WO2010065668A1
(en)
|
2008-12-03 |
2010-06-10 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of hcv ns5a
|
JP2012517478A
(ja)
|
2009-02-12 |
2012-08-02 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
ペグ化インターフェロン、リバビリンおよびテラプレビルを含む、hcv組合せ治療剤
|
EP2408753A4
(en)
*
|
2009-03-20 |
2012-11-07 |
Univ Brandeis |
COMPOUNDS AND METHOD FOR THE TREATMENT OF MICROBIAL STOMACH DARM INFECTIONS IN MAMMALS
|
JP5735482B2
(ja)
|
2009-03-27 |
2015-06-17 |
プレシディオ ファーマシューティカルズ インコーポレイテッド |
縮合環のc型肝炎阻害剤
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
WO2011014882A1
(en)
|
2009-07-31 |
2011-02-03 |
Medtronic, Inc. |
CONTINUOUS SUBCUTANEOUS ADMINISTRATION OF INTERFERON-α TO HEPATITIS C INFECTED PATIENTS
|
UA108211C2
(uk)
|
2009-11-04 |
2015-04-10 |
Янссен Рід Айрленд |
Бензімідазолімідазольні похідні
|
WO2011094489A1
(en)
|
2010-01-29 |
2011-08-04 |
Vertex Pharmaceuticals Incorporated |
Therapies for treating hepatitis c virus infection
|
WO2011112516A1
(en)
|
2010-03-08 |
2011-09-15 |
Ico Therapeutics Inc. |
Treating and preventing hepatitis c virus infection using c-raf kinase antisense oligonucleotides
|
WO2011149856A1
(en)
|
2010-05-24 |
2011-12-01 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of hcv ns5a
|
NZ604040A
(en)
|
2010-06-03 |
2015-02-27 |
Pharmacyclics Inc |
The use of inhibitors of bruton’s tyrosine kinase (btk)
|
WO2011156545A1
(en)
|
2010-06-09 |
2011-12-15 |
Vertex Pharmaceuticals Incorporated |
Viral dynamic model for hcv combination therapy
|
MX2012015198A
(es)
|
2010-06-24 |
2013-02-11 |
Janssen R & D Ireland |
Preparacion de acido 13-ciclohexil-3-metoxi-6-[metil-(2-{2-[metil- (sulfamoil)-amino]-etoxi}-etil)-carbomoil]-7h-indolo-[2,1-a]-[2]- benzazepin-10-carboxilico.
|
US20120014912A1
(en)
|
2010-07-14 |
2012-01-19 |
Vertex Pharmaceuticals Incorporated |
Palatable pharmaceutical composition
|
WO2012020036A1
(en)
|
2010-08-13 |
2012-02-16 |
F. Hoffmann-La Roche Ag |
Hepatitis c virus inhibitors
|
WO2012109646A1
(en)
|
2011-02-11 |
2012-08-16 |
Vertex Pharmaceuticals Incorporated |
Treatment of hcv in hiv infection patients
|
CN102985104A
(zh)
|
2011-02-25 |
2013-03-20 |
麦德托尼克公司 |
在干扰素-α治疗方案中使用药代动力学分布和药效动力学分布的方法和系统
|
WO2012123298A1
(en)
|
2011-03-11 |
2012-09-20 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
CN103732242A
(zh)
|
2011-06-23 |
2014-04-16 |
迪格纳生物技术公司 |
用与IFN-α2b组合的IFN-α5在患者群体中治疗慢性丙型肝炎
|
WO2012175581A1
(en)
|
2011-06-24 |
2012-12-27 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
KR101621181B1
(ko)
|
2011-10-10 |
2016-05-13 |
에프. 호프만-라 로슈 아게 |
항바이러스성 화합물
|
KR20140104030A
(ko)
|
2011-12-16 |
2014-08-27 |
에프. 호프만-라 로슈 아게 |
Hcv ns5a의 억제제
|
CN104011060A
(zh)
|
2011-12-20 |
2014-08-27 |
弗·哈夫曼-拉罗切有限公司 |
作为hcv rna复制抑制剂的4‘-叠氮基,3’-氟取代的核苷衍生物
|
MY171577A
(en)
|
2011-12-20 |
2019-10-21 |
Hoffmann La Roche |
2',4'-difluoro-2'-methyl substituted nucleoside derivatives as inhibitors of hcv rna replication
|
ES2558608T3
(es)
|
2011-12-28 |
2016-02-05 |
Janssen Sciences Ireland Uc |
Derivados hetero-bicíclicos como inhibidores del VHC
|
WO2013116339A1
(en)
|
2012-01-31 |
2013-08-08 |
Vertex Pharmaceuticals Incorporated |
High potency formulations of vx-950
|
CA2857262A1
(en)
|
2012-02-24 |
2013-08-29 |
F. Hoffmann-La Roche Ag |
Antiviral compounds
|
US8461179B1
(en)
|
2012-06-07 |
2013-06-11 |
Deciphera Pharmaceuticals, Llc |
Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
|
US20140010783A1
(en)
|
2012-07-06 |
2014-01-09 |
Hoffmann-La Roche Inc. |
Antiviral compounds
|
BR112015001690A2
(pt)
|
2012-07-24 |
2017-11-07 |
Pharmacyclics Inc |
mutações associadas com a resistência a inibidores da tirosina quinase de bruton (btk)
|
WO2014028931A2
(en)
|
2012-08-17 |
2014-02-20 |
Brandeis University |
Compounds and methods for treating mammalian gastrointestinal microbial infections
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
BR112015017414A2
(pt)
|
2013-01-23 |
2017-07-11 |
Hoffmann La Roche |
derivados de triazol antivirais
|
EP2964637B1
(en)
|
2013-03-05 |
2017-04-12 |
F. Hoffmann-La Roche AG |
Antiviral compounds
|
CA2912682C
(en)
|
2013-05-16 |
2021-07-06 |
Riboscience Llc |
4'-fluoro-2'-methyl substituted nucleoside derivatives
|
SG11201509427RA
(en)
|
2013-05-16 |
2015-12-30 |
Riboscience Llc |
4'-azido, 3'-deoxy-3'-fluoro substituted nucleoside derivatives
|
US20180200280A1
(en)
|
2013-05-16 |
2018-07-19 |
Riboscience Llc |
4'-Fluoro-2'-Methyl Substituted Nucleoside Derivatives as Inhibitors of HCV RNA Replication
|
JP6508785B2
(ja)
|
2013-10-25 |
2019-05-08 |
ファーマサイクリックス エルエルシー |
ブルトンチロシンキナーゼ阻害剤および免疫療法を使用する処置
|
CA2942528A1
(en)
|
2014-03-20 |
2015-09-24 |
Pharmacyclics Inc. |
Phospholipase c gamma 2 and resistance associated mutations
|
EP3684374B1
(en)
|
2017-09-21 |
2025-07-30 |
Riboscience LLC |
4'-fluoro-2'-methyl substituted nucleoside derivatives as inhibitors of hcv rna replication
|
EP3746060A1
(en)
|
2018-01-31 |
2020-12-09 |
Deciphera Pharmaceuticals, LLC |
Combination therapy for the treatment of mastocytosis
|
JP2021512105A
(ja)
|
2018-01-31 |
2021-05-13 |
デシフェラ・ファーマシューティカルズ,エルエルシー |
消化管間質腫瘍の治療のための併用療法
|
CA3094324A1
(en)
|
2018-03-26 |
2019-10-03 |
Clear Creek Bio, Inc. |
Compositions and methods for inhibiting dihydroorotate dehydrogenase
|
CN109970675A
(zh)
*
|
2018-05-28 |
2019-07-05 |
中国医学科学院医药生物技术研究所 |
一组硫脲化合物及其制备方法和应用
|
CN112313237A
(zh)
|
2018-06-19 |
2021-02-02 |
诺华股份有限公司 |
N-取代的四氢噻吩并吡啶衍生物及其用途
|
US12098117B2
(en)
*
|
2018-12-11 |
2024-09-24 |
Duke University |
Compositions and methods for the treatment of cancer
|
WO2021030405A1
(en)
|
2019-08-12 |
2021-02-18 |
Deciphera Pharmaceuticals, Llc |
Ripretinib for treating gastrointestinal stromal tumors
|
CA3150433A1
(en)
|
2019-08-12 |
2021-02-18 |
Deciphera Pharmaceuticals, Llc |
Ripretinib for treating gastrointestinal stromal tumors
|
CN110590535A
(zh)
*
|
2019-10-12 |
2019-12-20 |
重庆医药高等专科学校 |
用二氧化硒氧化芳香乙酮制备芳香乙醛酸的方法
|
AU2020419197B2
(en)
|
2019-12-30 |
2023-08-31 |
Deciphera Pharmaceuticals, Llc |
Amorphous kinase inhibitor formulations and methods of use thereof
|
CN118948773A
(zh)
|
2019-12-30 |
2024-11-15 |
德西费拉制药有限责任公司 |
1-(4溴-5-(1乙基-7-(甲氨基)-2侧氧基-1,2-二氢-1,6-萘啶-3基)-2氟苯基)-3-苯基脲的组合物
|
WO2021189018A1
(en)
|
2020-03-20 |
2021-09-23 |
Clear Creek Bio, Inc. |
Methods of treating viral infections using inhibitors of nucleotide synthesis pathways
|
WO2021209563A1
(en)
|
2020-04-16 |
2021-10-21 |
Som Innovation Biotech, S.A. |
Compounds for use in the treatment of viral infections by respiratory syndrome-related coronavirus
|
US11779572B1
(en)
|
2022-09-02 |
2023-10-10 |
Deciphera Pharmaceuticals, Llc |
Methods of treating gastrointestinal stromal tumors
|