SMT201400175B - Derivati amminopropionici sostituiti come inibitori di neprilisina - Google Patents

Derivati amminopropionici sostituiti come inibitori di neprilisina

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Publication number
SMT201400175B
SMT201400175B SM201400175T SM201400175T SMT201400175B SM T201400175 B SMT201400175 B SM T201400175B SM 201400175 T SM201400175 T SM 201400175T SM 201400175 T SM201400175 T SM 201400175T SM T201400175 B SMT201400175 B SM T201400175B
Authority
SM
San Marino
Prior art keywords
derivatives substituted
neprilysin inhibitors
aminopropionic
aminopropionic derivatives
neprilysin
Prior art date
Application number
SM201400175T
Other languages
English (en)
Italian (it)
Inventor
Gary Mark Coppola
Yuki Iwaki
Rajeshri Ganesh Karki
Toshio Kawanami
Gary Michael Ksander
Muneto Mogi
Robert Sun
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42313042&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201400175(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SMT201400175B publication Critical patent/SMT201400175B/xx

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    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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