DK2397480T3 - Diazepindionderivat - Google Patents

Diazepindionderivat

Info

Publication number
DK2397480T3
DK2397480T3 DK10741334.6T DK10741334T DK2397480T3 DK 2397480 T3 DK2397480 T3 DK 2397480T3 DK 10741334 T DK10741334 T DK 10741334T DK 2397480 T3 DK2397480 T3 DK 2397480T3
Authority
DK
Denmark
Prior art keywords
diazepindion
derivatives
diazepindion derivatives
Prior art date
Application number
DK10741334.6T
Other languages
English (en)
Inventor
Shogo Sakuma
Toshihiro Takahashi
Masatoshi Ushioda
Toshiyasu Imai
Kazuhide Inoue
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Application granted granted Critical
Publication of DK2397480T3 publication Critical patent/DK2397480T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
DK10741334.6T 2009-02-16 2010-02-15 Diazepindionderivat DK2397480T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009032705 2009-02-16
PCT/JP2010/052571 WO2010093061A1 (ja) 2009-02-16 2010-02-15 ジアゼピンジオン誘導体

Publications (1)

Publication Number Publication Date
DK2397480T3 true DK2397480T3 (da) 2013-09-02

Family

ID=42561898

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10741334.6T DK2397480T3 (da) 2009-02-16 2010-02-15 Diazepindionderivat

Country Status (10)

Country Link
US (2) US8470814B2 (da)
EP (1) EP2397480B1 (da)
JP (1) JP5592278B2 (da)
KR (1) KR101727761B1 (da)
CN (1) CN102395577B (da)
CA (1) CA2789641C (da)
DK (1) DK2397480T3 (da)
ES (1) ES2432265T3 (da)
PL (1) PL2397480T3 (da)
WO (1) WO2010093061A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2597088B1 (en) * 2010-07-13 2017-11-01 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist
EP2631229B1 (en) * 2010-07-29 2014-12-03 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist
CA2819997C (en) * 2010-11-05 2019-06-25 Kyushu University Preventive or therapeutic agent for pain associated with herpes zoster in acute phase
CA2840336C (en) * 2011-05-25 2020-06-30 Kyushu University Prophylactic or therapeutic agent for neuropathic pain associated with guillain-barre syndrome
SG10201605325TA (en) * 2012-01-13 2016-08-30 Nippon Chemiphar Co P2x4 receptor antagonist
EP3020707B1 (en) 2013-07-12 2019-08-21 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist
CA2921203C (en) * 2013-07-12 2021-07-27 Nippon Chemiphar Co., Ltd. Diazepinedione derivatives and compositions thereof useful as p2x4 receptor antagonist
CA2946669A1 (en) 2014-05-02 2015-11-05 Medimmune Limited Ion channel modulators & uses thereof
US11918589B2 (en) 2016-04-28 2024-03-05 Nippon Chemiphar Co., Ltd. Medicament for treatment of multiple sclerosis
US10695355B2 (en) * 2017-03-30 2020-06-30 University Of Connecticut Methods for pharmacologic treatment of stroke
US11666582B2 (en) 2018-03-14 2023-06-06 Nippon Chemiphar Co., Ltd. Medicament for treating cough
US20210205326A1 (en) * 2018-09-03 2021-07-08 Nippon Chemiphar Co., Ltd. Medicine for diabetic peripheral neuropathy
JP2022163241A (ja) * 2019-09-13 2022-10-26 日本ケミファ株式会社 P2x4受容体拮抗剤
AU2020439775A1 (en) * 2020-03-30 2022-11-03 Nippon Chemiphar Co., Ltd. Medicament for use in preventing or treating irritable bowel syndrome or inflammatory bowel disease
IL299383A (en) 2020-06-30 2023-02-01 Bayer Ag Use of N-phenylacetamides with P2X4 receptor antagonist activity to treat certain eye disorders
CN116437928A (zh) 2020-08-03 2023-07-14 日本化学药品株式会社 用于预防、抑制或治疗伴随着过敏反应的症状的医药组合物
IT202100025124A1 (it) 2021-09-30 2023-03-30 Univ Degli Studi Di Firenze Medicamento per uso nel prevenire o trattare il dolore nocicettivo e/o viscerale
WO2023054578A1 (ja) 2021-09-30 2023-04-06 日本ケミファ株式会社 呼吸器疾患の予防又は治療剤
WO2023157895A1 (ja) * 2022-02-17 2023-08-24 国立大学法人 鳥取大学 子宮内膜症又は子宮腺筋症の予防又は治療剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4969105A (en) 1988-05-02 1990-11-06 Ingersoll-Rand Company Gasket compression control method having tension-related feedback
DE10312969A1 (de) * 2003-03-24 2004-10-07 Bayer Healthcare Ag Benzofuro-1,4-diazepin-2-on-Derivate
CA2444161A1 (en) 2003-10-01 2005-04-01 Japan Health Sciences Foundation A screening method of drug for treatment of neuropathic pain
JP2009057281A (ja) 2005-12-19 2009-03-19 Nippon Chemiphar Co Ltd P2x4受容体拮抗剤
JP2009062278A (ja) 2005-12-29 2009-03-26 Nippon Chemiphar Co Ltd P2x4受容体拮抗剤
US20100256123A1 (en) 2006-08-25 2010-10-07 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist

Also Published As

Publication number Publication date
PL2397480T3 (pl) 2014-01-31
EP2397480A1 (en) 2011-12-21
CA2789641C (en) 2018-03-13
KR101727761B1 (ko) 2017-04-17
US8778933B2 (en) 2014-07-15
EP2397480B1 (en) 2013-08-14
CN102395577A (zh) 2012-03-28
US8470814B2 (en) 2013-06-25
EP2397480A4 (en) 2012-07-25
US20110319610A1 (en) 2011-12-29
CA2789641A1 (en) 2010-08-19
CN102395577B (zh) 2014-04-23
JPWO2010093061A1 (ja) 2012-08-16
US20130281441A1 (en) 2013-10-24
WO2010093061A1 (ja) 2010-08-19
JP5592278B2 (ja) 2014-09-17
KR20110120939A (ko) 2011-11-04
ES2432265T3 (es) 2013-12-02

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