PL2397480T3 - Pochodna diazepinodionu - Google Patents

Pochodna diazepinodionu

Info

Publication number
PL2397480T3
PL2397480T3 PL10741334T PL10741334T PL2397480T3 PL 2397480 T3 PL2397480 T3 PL 2397480T3 PL 10741334 T PL10741334 T PL 10741334T PL 10741334 T PL10741334 T PL 10741334T PL 2397480 T3 PL2397480 T3 PL 2397480T3
Authority
PL
Poland
Prior art keywords
diazepinedione derivative
diazepinedione
derivative
Prior art date
Application number
PL10741334T
Other languages
English (en)
Inventor
Shogo Sakuma
Toshihiro Takahashi
Masatoshi Ushioda
Toshiyasu Imai
Kazuhide Inoue
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of PL2397480T3 publication Critical patent/PL2397480T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/55171,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL10741334T 2009-02-16 2010-02-15 Pochodna diazepinodionu PL2397480T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2009032705 2009-02-16
EP10741334.6A EP2397480B1 (en) 2009-02-16 2010-02-15 Diazepinedione derivative
PCT/JP2010/052571 WO2010093061A1 (ja) 2009-02-16 2010-02-15 ジアゼピンジオン誘導体

Publications (1)

Publication Number Publication Date
PL2397480T3 true PL2397480T3 (pl) 2014-01-31

Family

ID=42561898

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10741334T PL2397480T3 (pl) 2009-02-16 2010-02-15 Pochodna diazepinodionu

Country Status (10)

Country Link
US (2) US8470814B2 (pl)
EP (1) EP2397480B1 (pl)
JP (1) JP5592278B2 (pl)
KR (1) KR101727761B1 (pl)
CN (1) CN102395577B (pl)
CA (1) CA2789641C (pl)
DK (1) DK2397480T3 (pl)
ES (1) ES2432265T3 (pl)
PL (1) PL2397480T3 (pl)
WO (1) WO2010093061A1 (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2597088B1 (en) * 2010-07-13 2017-11-01 Nippon Chemiphar Co., Ltd. P2x4 receptor antagonist
US8673915B2 (en) * 2010-07-29 2014-03-18 Nippon Chemiphar Co., Ltd. P 2×4 receptor antagonist
EP3132803B1 (en) 2010-11-05 2021-06-09 Kyushu University Preventive or therapeutic agent for pain associated with herpes zoster in acute phase
JP6325252B2 (ja) * 2011-05-25 2018-05-16 国立大学法人九州大学 ギラン・バレー症候群に伴う神経因性疼痛の予防又は治療剤
WO2013105608A1 (ja) * 2012-01-13 2013-07-18 日本ケミファ株式会社 P2x4受容体拮抗剤
JPWO2015005467A1 (ja) 2013-07-12 2017-03-02 日本ケミファ株式会社 P2x4受容体拮抗剤
JP6357475B2 (ja) * 2013-07-12 2018-07-11 日本ケミファ株式会社 P2x4受容体拮抗剤
AU2015254558B2 (en) 2014-05-02 2021-02-25 Medimmune Limited Ion channel modulators and uses thereof
US11918589B2 (en) 2016-04-28 2024-03-05 Nippon Chemiphar Co., Ltd. Medicament for treatment of multiple sclerosis
US10695355B2 (en) * 2017-03-30 2020-06-30 University Of Connecticut Methods for pharmacologic treatment of stroke
EP3766497A4 (en) 2018-03-14 2021-12-08 Nippon Chemiphar Co., Ltd. Drug for treating cough
WO2020050253A1 (ja) 2018-09-03 2020-03-12 日本ケミファ株式会社 糖尿病性末梢神経障害のための医薬
JP2022163241A (ja) * 2019-09-13 2022-10-26 日本ケミファ株式会社 P2x4受容体拮抗剤
US20230149421A1 (en) * 2020-03-30 2023-05-18 Universita' Di Pisa Medicament for preventing or treating irritable bowel syndrome or inflammatory bowel disease
EP4171744A1 (en) * 2020-06-30 2023-05-03 Bayer Aktiengesellschaft Use of n-phenylacetamides having p2x4 receptor antagonistic activity for treating certain ocular disorders
EP4190356A4 (en) 2020-08-03 2024-11-06 Nippon Chemiphar Co., Ltd. PHARMACEUTICAL COMPOSITION FOR THE PREVENTION, SUPPRESSION OR TREATMENT OF SYMPTOMS ASSOCIATED WITH AN ALLERGIC REACTION
IT202100025124A1 (it) * 2021-09-30 2023-03-30 Univ Degli Studi Di Firenze Medicamento per uso nel prevenire o trattare il dolore nocicettivo e/o viscerale
US20250375456A1 (en) 2021-09-30 2025-12-11 Nippon Chemiphar Co., Ltd. Agent for preventing or treating respiratory disease
JP2025041993A (ja) * 2022-02-17 2025-03-27 国立大学法人鳥取大学 子宮内膜症又は子宮腺筋症の予防又は治療剤
US20260000678A1 (en) 2022-03-31 2026-01-01 Takasaki University Of Health And Welfare Pharmaceutical composition for preventing, suppressing, or treating symptom associated with pseudo-allergic reaction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4969105A (en) 1988-05-02 1990-11-06 Ingersoll-Rand Company Gasket compression control method having tension-related feedback
DE10312969A1 (de) * 2003-03-24 2004-10-07 Bayer Healthcare Ag Benzofuro-1,4-diazepin-2-on-Derivate
CA2444161A1 (en) 2003-10-01 2005-04-01 Japan Health Sciences Foundation A screening method of drug for treatment of neuropathic pain
JP2009057281A (ja) 2005-12-19 2009-03-19 Nippon Chemiphar Co Ltd P2x4受容体拮抗剤
JP2009062278A (ja) 2005-12-29 2009-03-26 Nippon Chemiphar Co Ltd P2x4受容体拮抗剤
EP2058304A4 (en) 2006-08-25 2012-10-10 Nippon Chemiphar Co P2X4 RECEPTOR ANTAGONIST

Also Published As

Publication number Publication date
KR20110120939A (ko) 2011-11-04
US8470814B2 (en) 2013-06-25
US20130281441A1 (en) 2013-10-24
CN102395577A (zh) 2012-03-28
JP5592278B2 (ja) 2014-09-17
EP2397480B1 (en) 2013-08-14
US8778933B2 (en) 2014-07-15
CN102395577B (zh) 2014-04-23
EP2397480A1 (en) 2011-12-21
KR101727761B1 (ko) 2017-04-17
JPWO2010093061A1 (ja) 2012-08-16
CA2789641A1 (en) 2010-08-19
EP2397480A4 (en) 2012-07-25
DK2397480T3 (da) 2013-09-02
CA2789641C (en) 2018-03-13
WO2010093061A1 (ja) 2010-08-19
US20110319610A1 (en) 2011-12-29
ES2432265T3 (es) 2013-12-02

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