TW200611897A - Organic compounds - Google Patents

Organic compounds

Info

Publication number
TW200611897A
TW200611897A TW094123144A TW94123144A TW200611897A TW 200611897 A TW200611897 A TW 200611897A TW 094123144 A TW094123144 A TW 094123144A TW 94123144 A TW94123144 A TW 94123144A TW 200611897 A TW200611897 A TW 200611897A
Authority
TW
Taiwan
Prior art keywords
organic compounds
compounds
medicaments
preparation
general formula
Prior art date
Application number
TW094123144A
Other languages
Chinese (zh)
Inventor
Peter Herold
Robert Mah
Vincenzo Tschinke
Christoph Schumacher
Christiane Marti
Michael Quirmbach
Original Assignee
Speedel Experimenta Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Experimenta Ag filed Critical Speedel Experimenta Ag
Publication of TW200611897A publication Critical patent/TW200611897A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems

Abstract

The application relates to novel heterocyclic compounds of the general formula, in which R1, R2, V, W, X, Y, Z and n have the meanings defined in the description, to a process for their preparation and to the use of these compounds as medicaments, in particular as aldosterone synthase inhibitors.
TW094123144A 2004-07-09 2005-07-08 Organic compounds TW200611897A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH11562004 2004-07-09

Publications (1)

Publication Number Publication Date
TW200611897A true TW200611897A (en) 2006-04-16

Family

ID=35457694

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094123144A TW200611897A (en) 2004-07-09 2005-07-08 Organic compounds

Country Status (3)

Country Link
AR (1) AR049711A1 (en)
TW (1) TW200611897A (en)
WO (1) WO2006005726A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1842543A1 (en) * 2006-04-05 2007-10-10 Speedel Pharma AG Pharmaceutical composition coprising an aldosterone synthase inhibitor and a mineralcorticoid receptor antagonist
TW200808813A (en) * 2006-04-12 2008-02-16 Speedel Experimenta Ag Imidazo compounds
EP1886695A1 (en) * 2006-06-27 2008-02-13 Speedel Experimenta AG Pharmaceutical combination of an aldosterone synthase inhibitor and a glucocorticoid receptor antagonist or a cortisol synthesis inhibitor or a corticotropin releasing factor antagonist
PT2435409E (en) 2009-05-28 2014-11-05 Novartis Ag Substituted aminopropionic derivatives as neprilysin inhibitors
JP5466759B2 (en) 2009-05-28 2014-04-09 ノバルティス アーゲー Substituted aminobutyric acid derivatives as neprilysin inhibitors
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
PT2729142T (en) 2011-07-08 2018-10-01 Novartis Ag Method of treating atherosclerosis in high triglyceride subjects
UY35144A (en) 2012-11-20 2014-06-30 Novartis Ag APELINE SYNTHETIC LINEAR MIMETICS FOR THE CARDIAC INSUFFICIENCY TREATMENT
EA028583B1 (en) 2013-02-14 2017-12-29 Новартис Аг Substituted bisphenyl butanoic phosphonic acid derivatives as nep (neutral endopeptidase) inhibitors
MX2016001020A (en) 2013-07-25 2016-08-03 Novartis Ag Cyclic polypeptides for the treatment of heart failure.
TW201518323A (en) 2013-07-25 2015-05-16 Novartis Ag Bioconjugates of synthetic APELIN polypeptides
EP3247405B1 (en) 2015-01-23 2019-07-17 Novartis AG Synthetic apelin fatty acid conjugates with improved half-life
JOP20190086A1 (en) 2016-10-21 2019-04-18 Novartis Ag Naphthyridinone derivatives and their use in the treatment of arrhythmia
UY38072A (en) 2018-02-07 2019-10-01 Novartis Ag COMPOSITIONS DERIVED FROM BUTANOIC ESTER SUBSTITUTED WITH BISPHENYL AS INHIBITORS OF NEP, COMPOSITIONS AND COMBINATIONS OF THE SAME
UY38485A (en) 2018-11-27 2020-06-30 Novartis Ag CYCLIC TETRAMER COMPOUNDS AS PROPROTEIN CONVERTASE SUBTILISIN / KEXIN TYPE 9 (PCSK9) INHIBITORS, METHOD OF TREATMENT, USE AND PREPARATION
EP3887363A1 (en) 2018-11-27 2021-10-06 Novartis AG Cyclic pentamer compounds as proprotein convertase subtilisin/kexin type 9 (pcsk9) inhibitors for the treatment of metabolic disorder
CN113166204A (en) 2018-11-27 2021-07-23 诺华股份有限公司 Cyclic peptides as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders
WO2023084449A1 (en) 2021-11-12 2023-05-19 Novartis Ag Diaminocyclopentylpyridine derivatives for the treatment of a disease or disorder
AR127698A1 (en) 2021-11-23 2024-02-21 Novartis Ag NAFTYRIDINOONE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0313293A (en) * 2002-08-07 2005-06-14 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
WO2006005726A2 (en) 2006-01-19
WO2006005726A3 (en) 2006-05-04
AR049711A1 (en) 2006-08-30

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