IT1148006B - Ammidi dotate di proprieta' farmaceutiche e loro preparazione - Google Patents

Ammidi dotate di proprieta' farmaceutiche e loro preparazione

Info

Publication number
IT1148006B
IT1148006B IT48261/81A IT4826181A IT1148006B IT 1148006 B IT1148006 B IT 1148006B IT 48261/81 A IT48261/81 A IT 48261/81A IT 4826181 A IT4826181 A IT 4826181A IT 1148006 B IT1148006 B IT 1148006B
Authority
IT
Italy
Prior art keywords
starches
preparation
pharmaceutical properties
pharmaceutical
properties
Prior art date
Application number
IT48261/81A
Other languages
English (en)
Other versions
IT8148261A0 (it
Inventor
Samuel Wilkinson
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IT8148261A0 publication Critical patent/IT8148261A0/it
Application granted granted Critical
Publication of IT1148006B publication Critical patent/IT1148006B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
IT48261/81A 1980-04-11 1981-04-10 Ammidi dotate di proprieta' farmaceutiche e loro preparazione IT1148006B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8011986 1980-04-11

Publications (2)

Publication Number Publication Date
IT8148261A0 IT8148261A0 (it) 1981-04-10
IT1148006B true IT1148006B (it) 1986-11-26

Family

ID=10512731

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48261/81A IT1148006B (it) 1980-04-11 1981-04-10 Ammidi dotate di proprieta' farmaceutiche e loro preparazione

Country Status (5)

Country Link
EP (1) EP0038046B1 (it)
JP (1) JPS56158746A (it)
DE (1) DE3162404D1 (it)
GB (1) GB2074571B (it)
IT (1) IT1148006B (it)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2480747A1 (fr) * 1980-04-17 1981-10-23 Roques Bernard Derives d'acides amines et leur application therapeutique
US4329495A (en) * 1981-05-18 1982-05-11 Pfizer Inc. Enkephalinase enzyme inhibiting compounds
NZ201998A (en) * 1981-09-25 1985-11-08 Wellcome Found Amides and pharmaceutical compositions
JPS58140065A (ja) * 1982-02-10 1983-08-19 Meito Sangyo Kk メルカプトベンジル脂肪酸誘導体類及びその製法
AU594645B2 (en) * 1984-06-08 1990-03-15 Ciba-Geigy Ag N-substituted butyramide derivatives
US4853476A (en) * 1984-12-24 1989-08-01 Schering Corporation Phosphorus containing compounds as inhibitors of enkephalinases
US5166212A (en) * 1985-12-06 1992-11-24 Ciba-Geigy Corporation Certain n-substituted butyramide derivatives
EP0225292A3 (en) * 1985-12-06 1988-11-30 Ciba-Geigy Ag Certain n-substituted butyramide derivatives
EP0566157A1 (en) * 1986-06-20 1993-10-20 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
US4801609B1 (en) * 1987-03-27 1993-11-09 Mercapto-acylamino acid antihypertensives
US4929641B1 (en) * 1988-05-11 1994-08-30 Schering Corp Mercapto-acylamino acid antihypertensives
EP0254032A3 (en) * 1986-06-20 1990-09-05 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
US5210266A (en) * 1987-12-03 1993-05-11 Dainippon Pharmaceutical Co., Ltd. N-substituted mercaptopropanamide derivatives
US5179125A (en) * 1987-12-03 1993-01-12 Dainippon Pharmaceutical Co., Ltd. N-substituted mercaptopropanamide derivatives
JP2848411B2 (ja) * 1988-08-18 1999-01-20 サイオス インコーポレイテッド 心房性ナトリウム利尿ペプチドクリアランス阻害剤
US4879309A (en) * 1988-09-27 1989-11-07 Schering Corporation Mercapto-acylamino acids as antihypertensives
ZA902661B (en) * 1989-04-10 1991-01-30 Schering Corp Mercapto-acyl amino acids
US5599951A (en) * 1989-09-15 1997-02-04 Societe Civile Bioprojet Amino acid derivatives, the process for their preparation and their applications to therapy
FR2652087B1 (fr) * 1989-09-15 1993-10-15 Bioprojet Ste Civile Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques.
WO1991007386A1 (en) * 1989-11-21 1991-05-30 Schering Corporation Carboxyalkylcarbonyl aminoacid endopeptidase inhibitors
US5075302A (en) * 1990-03-09 1991-12-24 Schering Corporation Mercaptoacyl aminolactam endopeptidase inhibitors
WO1994007481A1 (en) * 1992-10-02 1994-04-14 Merck & Co., Inc. N-(mercaptoacyl)peptidyl derivatives as antidegenerative agents
EP0640594A1 (en) 1993-08-23 1995-03-01 Fujirebio Inc. Hydantoin derivative as metalloprotease inhibitor
KR20010033069A (ko) * 1997-12-12 2001-04-25 후지 야꾸힝 고교 가부시키가이샤 신규한 메탈로프로테이나제 억제제
ES2582395T3 (es) 2009-05-28 2016-09-12 Novartis Ag Derivados aminobutíricos sustituidos como inhibidores de neprilisina
CN102574801B (zh) 2009-05-28 2016-04-27 诺华股份有限公司 作为脑啡肽酶抑制剂的取代的氨基丙酸衍生物
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
WO2014126972A1 (en) 2013-02-14 2014-08-21 Novartis Ag Substituted bisphenyl butanoic acid derivatives as nep inhibitors with improved in vivo efficacy
AP2015008621A0 (en) 2013-02-14 2015-07-31 Novartis Ag Substituted bisphenyl butanoic nep 'neutral endopeptidase' inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2463939A (en) * 1945-08-24 1949-03-08 Lilly Co Eli Phenylacetyl amino acid esters
DE1146066B (de) * 1956-09-05 1963-03-28 Takeda Pharmaceutical Verfahren zur Herstellung von therapeutisch wirksamem N-(ª‡-Phenylbutyryl)-dl-methionin und N-(ª‡-Phenylbutyryl)-taurin
FR1458106A (fr) * 1964-01-30 1966-03-04 Merck & Co Inc Nouvelles amides d'acides n-carboxyalkyl-phénoxyalcanoïques et d'acides n-carboxyalkyl-anilinoalcanoïques

Also Published As

Publication number Publication date
EP0038046A2 (en) 1981-10-21
EP0038046B1 (en) 1984-02-29
GB2074571B (en) 1984-02-15
EP0038046A3 (en) 1982-01-20
IT8148261A0 (it) 1981-04-10
DE3162404D1 (en) 1984-04-05
JPS56158746A (en) 1981-12-07
GB2074571A (en) 1981-11-04

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