SMT201400150B - Composizioni terapeutiche comprendenti rilpivirinacloridrato e tenofovir disoproxil fumarato - Google Patents

Composizioni terapeutiche comprendenti rilpivirinacloridrato e tenofovir disoproxil fumarato

Info

Publication number
SMT201400150B
SMT201400150B SM201400150T SM201400150T SMT201400150B SM T201400150 B SMT201400150 B SM T201400150B SM 201400150 T SM201400150 T SM 201400150T SM 201400150 T SM201400150 T SM 201400150T SM T201400150 B SMT201400150 B SM T201400150B
Authority
SM
San Marino
Prior art keywords
rilpivirinchlorhydrate
therapeutic compositions
tenofovir disoproxil
disoproxil fumarate
fumarate
Prior art date
Application number
SM201400150T
Other languages
English (en)
Italian (it)
Inventor
Reza Oliyai
Lauren Wiser
Mark Menning
Original Assignee
Janssen R & D Ireland
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45094284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201400150(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen R & D Ireland, Gilead Sciences Inc filed Critical Janssen R & D Ireland
Publication of SMT201400150B publication Critical patent/SMT201400150B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SM201400150T 2010-11-19 2014-10-16 Composizioni terapeutiche comprendenti rilpivirinacloridrato e tenofovir disoproxil fumarato SMT201400150B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41560010P 2010-11-19 2010-11-19
PCT/US2011/061515 WO2012068535A1 (en) 2010-11-19 2011-11-18 Therapeutic compositions comprising rilpivirine hcl and tenofovir disoproxil fumarate

Publications (1)

Publication Number Publication Date
SMT201400150B true SMT201400150B (it) 2015-01-15

Family

ID=45094284

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201400150T SMT201400150B (it) 2010-11-19 2014-10-16 Composizioni terapeutiche comprendenti rilpivirinacloridrato e tenofovir disoproxil fumarato

Country Status (35)

Country Link
US (1) US10857102B2 (xx)
EP (2) EP2640362B2 (xx)
JP (2) JP2014500261A (xx)
KR (1) KR101923103B1 (xx)
CN (2) CN106511357A (xx)
AP (1) AP3816A (xx)
AR (2) AR084500A1 (xx)
AU (3) AU2011329642B2 (xx)
BR (1) BR112013012245B1 (xx)
CA (1) CA2818097C (xx)
CL (1) CL2013001402A1 (xx)
CO (1) CO6761300A2 (xx)
CR (1) CR20130293A (xx)
DK (1) DK2640362T4 (xx)
EA (2) EA025852B1 (xx)
EC (2) ECSP13012700A (xx)
ES (1) ES2524408T5 (xx)
HK (2) HK1190064A1 (xx)
HR (1) HRP20140946T1 (xx)
IL (1) IL226300B (xx)
MA (1) MA34735B1 (xx)
ME (1) ME01980B (xx)
MX (1) MX347512B (xx)
MY (1) MY185604A (xx)
NZ (1) NZ610729A (xx)
PE (3) PE20140163A1 (xx)
PL (1) PL2640362T5 (xx)
PT (1) PT2640362E (xx)
RS (1) RS53691B1 (xx)
SG (3) SG10201912527XA (xx)
SM (1) SMT201400150B (xx)
TW (1) TWI556840B (xx)
UA (1) UA114075C2 (xx)
WO (1) WO2012068535A1 (xx)
ZA (1) ZA201304481B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040224917A1 (en) 2003-01-14 2004-11-11 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
KR101923103B1 (ko) 2010-11-19 2018-11-28 길리애드 사이언시즈, 인코포레이티드 릴피비린 hcl 및 테노포비어 디소프록실 푸마레이트를 포함하는 치료 조성물
AU2012296622C1 (en) 2011-08-16 2017-02-16 Gilead Sciences, Inc. Tenofovir alafenamide hemifumarate
CA2779052A1 (en) * 2012-05-31 2013-11-30 Pharmascience Inc. Pharmaceutical composition of entecavir and process of manufacturing
KR102527797B1 (ko) 2012-12-21 2023-05-03 길리애드 사이언시즈, 인코포레이티드 폴리시클릭-카르바모일피리돈 화합물 및 그의 제약 용도
EP2832351A1 (en) * 2013-07-29 2015-02-04 Sanovel Ilac Sanayi ve Ticaret A.S. Multilayer Tablet Formulations Comprising Tenofovir and Entecavir
CZ2013985A3 (cs) * 2013-12-09 2015-06-17 Zentiva, K.S. Stabilní farmaceutická kompozice obsahující tenofovir disoproxil fumarát
WO2015152433A1 (en) * 2014-03-31 2015-10-08 Hanmi Pharm. Co., Ltd. Amorphous solid dispersion comprising paclitaxel, tablet comprising the same, and method for preparing the same
ES2892123T3 (es) 2014-12-26 2022-02-02 Univ Emory Derivados antivíricos de N4-hidroxicitidina
US9839212B2 (en) 2015-04-16 2017-12-12 Bio-Lab, Inc. Multicomponent and multilayer compacted tablets
CA2921336A1 (en) * 2015-06-30 2016-12-30 Gilead Sciences, Inc. Pharmaceutical formulations
KR20170003063A (ko) * 2015-06-30 2017-01-09 한미약품 주식회사 테노포비어 디소프록실 함유 경구용 고형제제 및 그 제조방법
TWI737647B (zh) 2015-11-09 2021-09-01 美商基利科學股份有限公司 用於治療人類免疫缺乏病毒之治療組合物
US20190060325A1 (en) * 2016-04-08 2019-02-28 Shionogi & Co., Ltd. Stabilized solid dosage form
TR201617448A2 (tr) * 2016-11-29 2018-06-21 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Tenofovi̇r ve emtri̇si̇tabi̇n i̇çeren kati oral farmasöti̇k bi̇leşi̇mler
US10561614B2 (en) * 2017-01-27 2020-02-18 Steerlife India Private Limited Tenofovir granules
WO2019003150A2 (en) * 2017-06-30 2019-01-03 Viiv Healthcare Company ASSOCIATION, USES AND THERAPEUTIC DIAGRAMS
GB2581936B (en) 2017-12-07 2021-02-10 Univ Emory N4-hydroxycytidine and derivatives and anti-viral uses related thereto
JP2022538338A (ja) * 2019-07-03 2022-09-01 ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー リルピビリンを用いて小児患者におけるｈｉｖを治療する方法
CN112137981A (zh) * 2020-11-02 2020-12-29 成都晶富医药科技有限公司 富马酸丙酚替诺福韦片及其制备工艺

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ250842A (en) 1991-02-22 1996-03-26 Univ Emory Resolution of a racemic mixture of nucleoside enantiomers such as 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane (ftc)
MY169670A (en) * 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
JO3429B1 (ar) 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
EP1448170A4 (en) 2001-11-27 2010-05-12 Bristol Myers Squibb Co EFAVIRENZ STAMP PREPARATIONS HAVING UNIQUE BIOPHARMACEUTICAL CHARACTERISTICS
US20040224917A1 (en) 2003-01-14 2004-11-11 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
PL1632232T6 (pl) 2004-09-02 2022-06-27 Janssen Pharmaceutica Nv Sól 4-[[4-[[4-(2-cyjanoetenylo)-2,6-dimetylofenylo]amino]-2-pirymidynylo]amino]benzonitrylu
SI1632232T1 (sl) 2004-09-02 2011-09-30 Janssen Pharmaceutica Nv Sol 4((4((4-(2-cianoetenil)-2,6-dimetilfenil)amino)-2-pirimidinil)amino) benzonitrila
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
CA2625776A1 (en) 2005-10-14 2007-04-26 Microdose Technologies, Inc. Pharmaceutical packaging of an oral dosage combination
AU2006325404B2 (en) 2005-12-14 2012-03-01 Cipla Limited Pharmaceutical combination comprising nucleotide and nucleoside reverse transcriptase inhibitors (such as tenofovir and lamivudine) in different parts of the dosage unit
ES2603617T3 (es) * 2007-02-23 2017-02-28 Gilead Sciences, Inc. Moduladores de propiedades farmacocinéticas de la terapéutica
WO2008140461A1 (en) 2007-05-16 2008-11-20 Fmc Corporation Solid form
US20080286344A1 (en) 2007-05-16 2008-11-20 Olivia Darmuzey Solid form
EP2160394A1 (en) 2007-05-22 2010-03-10 Ultimorphix Technologies B.v. Tenofovir disoproxil hemi-fumaric acid co-crystal
WO2009037449A1 (en) 2007-09-18 2009-03-26 Cipla Limited Solid pharmaceutical compositions comprising one or more herpes virus inhibitors and one or more reverse transcriptase inhibitors
WO2009106960A2 (en) 2008-02-27 2009-09-03 Aurobindo Pharma Limited Stable compositions of lamivudine, tenofovir and efavirenz
KR101784647B1 (ko) 2008-05-02 2017-10-11 길리애드 사이언시즈, 인코포레이티드 제약 제제의 가공성 향상을 위한 고체 담체 입자의 용도
AP3250A (en) 2009-02-06 2015-05-31 Gilead Sciences Inc Tablets for combination therapy
PE20160217A1 (es) 2009-09-21 2016-05-18 Gilead Sciences Inc Analogos de carba-nucleosidos sustituidos con 2'-fluoro antivirales
WO2011077100A1 (en) 2009-12-24 2011-06-30 Cipla Limited Antiretroviral composition
KR101923103B1 (ko) 2010-11-19 2018-11-28 길리애드 사이언시즈, 인코포레이티드 릴피비린 hcl 및 테노포비어 디소프록실 푸마레이트를 포함하는 치료 조성물

Also Published As

Publication number Publication date
AP2013006931A0 (en) 2013-06-30
AU2018202635A1 (en) 2018-05-10
EP2826466A1 (en) 2015-01-21
EP2640362A1 (en) 2013-09-25
KR101923103B1 (ko) 2018-11-28
CA2818097A1 (en) 2012-05-24
HRP20140946T1 (hr) 2015-02-13
AU2011329642B2 (en) 2016-08-11
HK1190064A1 (en) 2014-06-27
AR084500A1 (es) 2013-05-22
MX347512B (es) 2017-04-28
JP2015131853A (ja) 2015-07-23
WO2012068535A1 (en) 2012-05-24
EA201390651A1 (ru) 2013-11-29
PT2640362E (pt) 2014-11-28
DK2640362T4 (da) 2022-03-07
ECSP19078196A (es) 2019-11-30
MX2013005669A (es) 2013-11-04
CO6761300A2 (es) 2013-09-30
ECSP13012700A (es) 2013-08-30
CN106511357A (zh) 2017-03-22
ZA201304481B (en) 2022-03-30
KR20140037799A (ko) 2014-03-27
EP2640362B2 (en) 2021-12-01
HK1206592A1 (en) 2016-01-15
EP2640362B1 (en) 2014-09-10
AP3816A (en) 2016-09-30
EA025852B1 (ru) 2017-02-28
PE20170521A1 (es) 2017-05-27
CN103491948A (zh) 2014-01-01
SG10201509521WA (en) 2015-12-30
CL2013001402A1 (es) 2013-12-27
ES2524408T5 (es) 2022-04-25
PE20140163A1 (es) 2014-02-08
AU2011329642A1 (en) 2013-05-02
AR123409A2 (es) 2022-11-30
JP2014500261A (ja) 2014-01-09
TW201238612A (en) 2012-10-01
TWI556840B (zh) 2016-11-11
CA2818097C (en) 2019-07-30
IL226300B (en) 2019-05-30
US10857102B2 (en) 2020-12-08
BR112013012245B1 (pt) 2022-09-27
MA34735B1 (fr) 2013-12-03
PL2640362T3 (pl) 2015-03-31
UA114075C2 (xx) 2017-04-25
MY185604A (en) 2021-05-25
SG190333A1 (en) 2013-06-28
AU2016208417B2 (en) 2018-04-05
NZ610729A (en) 2015-10-30
AU2016208417A1 (en) 2016-08-18
CN103491948B (zh) 2016-11-02
RS53691B1 (en) 2015-04-30
EA201691695A1 (ru) 2017-11-30
ES2524408T3 (es) 2014-12-09
CR20130293A (es) 2013-10-03
JP6138851B2 (ja) 2017-05-31
ME01980B (me) 2015-05-20
US20130243857A1 (en) 2013-09-19
SG10201912527XA (en) 2020-02-27
BR112013012245A2 (pt) 2016-08-09
PL2640362T5 (pl) 2022-05-02
DK2640362T3 (en) 2014-12-01
PE20211657A1 (es) 2021-08-24

Similar Documents

Publication Publication Date Title
SMT201400150B (it) Composizioni terapeutiche comprendenti rilpivirinacloridrato e tenofovir disoproxil fumarato
SMT201600049B (it) Formulazioni di apixaban
DK2525798T3 (da) Anæstetisk formulering
DK2648809T3 (da) Naturlige formuleringer
DK3170508T3 (da) Vaccineformuleringer
DK2539015T3 (da) Nethindeprotese
CO6811815A2 (es) Composiciones de nucleasa terapéuticas y métodos
GT201200303A (es) Formulaciones farmacéuticas
HK1201454A1 (en) Therapeutic agents and uses thereof
ITTO20110641A1 (it) Composizioni farmaceutiche e metodi di trattamento
GB2501611B (en) Alpha-2-macroglobulin compositions and therapeutic uses
DK2745849T3 (da) Polydeoxyribonukleotidsammensætning og anvendelser deraf
SG10201606161UA (en) Albumin Formulation and Use
EP2864345A4 (en) NUCLEIC ACID PARTICLE CONJUGATES AND THERAPEUTIC APPLICATIONS THEREOF
EP2895186A4 (en) THERAPEUTIC COMPOSITIONS AND RELATED METHODS
BR112014010152A2 (pt) formulação esporicida e lenço
CO6990712A2 (es) Combinación farmacéutica antineuritica y composiciones
DE102012022654A8 (de) Dentales Implantat
ES1076359Y (es) Implante dental
FR2967069B3 (fr) Formulations
DK2598472T3 (da) Formuleringer
SI2640362T2 (sl) Terapevtski sestavki, ki vsebujejo rilpivirin hcl in tenovofir disoproksil
IL229936B (en) Albumin formulation and use
FI20105855A0 (fi) Transdermaaliset koostumukset ihmiskäyttöön
ITAL20100009A1 (it) "magic carpet"