SI1632232T1 - Sol 4((4((4-(2-cianoetenil)-2,6-dimetilfenil)amino)-2-pirimidinil)amino) benzonitrila - Google Patents
Sol 4((4((4-(2-cianoetenil)-2,6-dimetilfenil)amino)-2-pirimidinil)amino) benzonitrilaInfo
- Publication number
- SI1632232T1 SI1632232T1 SI200531339T SI200531339T SI1632232T1 SI 1632232 T1 SI1632232 T1 SI 1632232T1 SI 200531339 T SI200531339 T SI 200531339T SI 200531339 T SI200531339 T SI 200531339T SI 1632232 T1 SI1632232 T1 SI 1632232T1
- Authority
- SI
- Slovenia
- Prior art keywords
- åamino
- cyanoethenyl
- dimethylphenyl
- pyrimidinyl
- salt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
MYPI20043578A MY169670A (en) | 2003-09-03 | 2004-09-02 | Combinations of a pyrimidine containing nnrti with rt inhibitors |
PCT/EP2004/052028 WO2005021001A1 (en) | 2003-09-03 | 2004-09-03 | Combinations of a pyrimidine containing nnrti with rt inhibitors |
EP05101467 | 2005-02-25 | ||
EP05108086.9A EP1632232B3 (en) | 2004-09-02 | 2005-09-02 | Salt of 4[[4-[[4-(2-Cyanoethenyl)-2,6-dimethylphenyl]amino]-2-Pyrimidinyl]amino]benzonitrile |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1632232T1 true SI1632232T1 (sl) | 2011-09-30 |
Family
ID=38091637
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200531339T SI1632232T1 (sl) | 2004-09-02 | 2005-09-02 | Sol 4((4((4-(2-cianoetenil)-2,6-dimetilfenil)amino)-2-pirimidinil)amino) benzonitrila |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1632232B3 (sl) |
JP (1) | JP4912309B2 (sl) |
CN (1) | CN104586850A (sl) |
AT (1) | ATE508748T1 (sl) |
BR (1) | BRPI0514871A (sl) |
CY (3) | CY1112249T1 (sl) |
DK (1) | DK1632232T6 (sl) |
EA (1) | EA013686B1 (sl) |
ES (1) | ES2371442T7 (sl) |
FR (2) | FR16C1025I1 (sl) |
HK (1) | HK1210029A1 (sl) |
HU (2) | HUS1600060I1 (sl) |
IL (1) | IL181650A (sl) |
LT (2) | LTPA2016043I1 (sl) |
ME (1) | ME01246B (sl) |
MX (1) | MX2007002595A (sl) |
NI (1) | NI200700068A (sl) |
NO (3) | NO340654B1 (sl) |
PT (1) | PT1632232E (sl) |
RS (1) | RS51923B2 (sl) |
SI (1) | SI1632232T1 (sl) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY169670A (en) | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
KR101501475B1 (ko) * | 2006-01-20 | 2015-03-19 | 얀센 알 앤드 디 아일랜드 | Tmc278을 이용한 hiv 감염의 장기간 요법 |
CL2008000746A1 (es) | 2007-03-14 | 2008-09-22 | Tibotec Pharm Ltd | Composicion farmaceutica en solucion que comprende tmc278 y un polimero soluble en agua; proceso de preparacion de dicha composicion; y uso de un polvo que comprende tmc278 para tratar sida. |
MX347512B (es) | 2010-11-19 | 2017-04-28 | Gilead Sciences Inc | Composiciones terapeuticas que comprenden hcl de rilpivirina y fumarato de disoproxilo de tenofovir. |
US8952155B2 (en) * | 2011-04-15 | 2015-02-10 | Emcure Pharmaceuticals Limited | Rilpivirine process |
EP2628732A1 (en) * | 2012-02-20 | 2013-08-21 | Sandoz AG | Novel crystalline form of rilpivirine hydrochloride |
EP2604593A1 (en) | 2011-12-14 | 2013-06-19 | Sandoz AG | Polymorph of Rilpivirine hydrochloride and its use as antiviral |
WO2013087794A1 (en) | 2011-12-14 | 2013-06-20 | Sandoz Ag | Polymorph of rilpivirine hydrochloride and its use as antiviral |
WO2013153162A1 (en) * | 2012-04-11 | 2013-10-17 | Sandoz Ag | Polymorph of rilpivirine hydrochloride |
WO2013153161A2 (en) * | 2012-04-11 | 2013-10-17 | Sandoz Ag | Novel polymorph of rilpivirine hydrochloride |
CN103570688B (zh) * | 2012-07-19 | 2016-06-08 | 中国科学院上海药物研究所 | 2,5-二氨甲基吡嗪类化合物、其药物组合物、制备方法和用途 |
GR1008965B (el) * | 2015-12-02 | 2017-02-28 | Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων | Φαρμακευτικο σκευασμα που περιλαμβανει δαρουναβιρη και μεθοδος παρασκευης αυτου |
RU2616267C1 (ru) * | 2016-01-25 | 2017-04-13 | Закрытое Акционерное Общество "БИОКОМ" | Твердая лекарственная форма индинавира немедленного высвобождения и способ ее получения |
RU2019115672A (ru) * | 2016-10-24 | 2020-11-24 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Диспергируемые композиции |
CN114392241B (zh) * | 2022-01-10 | 2023-07-25 | 安徽贝克生物制药有限公司 | 一种利匹韦林片及其制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6307543B1 (en) * | 1998-09-10 | 2001-10-23 | Silicon Image, Inc. | Bi-directional data transfer using two pair of differential lines as a single additional differential pair |
JO3429B1 (ar) * | 2001-08-13 | 2019-10-20 | Janssen Pharmaceutica Nv | مشتقات برميدينات مثبطة فيروس الايدز |
MY169670A (en) * | 2003-09-03 | 2019-05-08 | Tibotec Pharm Ltd | Combinations of a pyrimidine containing nnrti with rt inhibitors |
KR101140785B1 (ko) * | 2002-08-09 | 2012-05-03 | 얀센 파마슈티카 엔.브이. | 4-〔〔4-〔〔4-(2-시아노에테닐)-2,6-디메틸페닐〕아미노〕-2-피리미디닐〕아미노〕벤조니트릴의 제조방법 |
WO2004050068A1 (en) * | 2002-11-29 | 2004-06-17 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base |
EA011164B1 (ru) * | 2003-02-07 | 2009-02-27 | Янссен Фармацевтика Н. В. | Производные пиримидина для профилактики вич-инфекции |
-
2005
- 2005-09-02 AT AT05108086T patent/ATE508748T1/de active
- 2005-09-02 EA EA200700536A patent/EA013686B1/ru active Protection Beyond IP Right Term
- 2005-09-02 PT PT05108086T patent/PT1632232E/pt unknown
- 2005-09-02 BR BRPI0514871-5A patent/BRPI0514871A/pt not_active Application Discontinuation
- 2005-09-02 DK DK05108086.9T patent/DK1632232T6/da active
- 2005-09-02 JP JP2007528886A patent/JP4912309B2/ja active Active
- 2005-09-02 MX MX2007002595A patent/MX2007002595A/es active IP Right Grant
- 2005-09-02 SI SI200531339T patent/SI1632232T1/sl unknown
- 2005-09-02 RS RS20110355A patent/RS51923B2/sr unknown
- 2005-09-02 ME MEP-2011-144A patent/ME01246B/me unknown
- 2005-09-02 ES ES05108086T patent/ES2371442T7/es active Active
- 2005-09-02 EP EP05108086.9A patent/EP1632232B3/en active Active
- 2005-09-02 CN CN201510012919.7A patent/CN104586850A/zh active Pending
-
2007
- 2007-03-01 NI NI200700068A patent/NI200700068A/es unknown
- 2007-03-01 IL IL181650A patent/IL181650A/en active IP Right Grant
- 2007-04-02 NO NO20071745A patent/NO340654B1/no active Protection Beyond IP Right Term
-
2011
- 2011-08-10 CY CY20111100775T patent/CY1112249T1/el unknown
-
2015
- 2015-11-03 HK HK15110805.7A patent/HK1210029A1/xx unknown
-
2016
- 2016-12-20 HU HUS1600060C patent/HUS1600060I1/hu unknown
- 2016-12-20 FR FR16C1025C patent/FR16C1025I1/fr active Active
- 2016-12-20 CY CY2016051C patent/CY2016051I1/el unknown
- 2016-12-20 FR FR16C1023C patent/FR16C1023I1/fr active Active
- 2016-12-20 LT LTPA2016043C patent/LTPA2016043I1/lt unknown
- 2016-12-20 CY CY2016050C patent/CY2016050I1/el unknown
- 2016-12-20 HU HUS1600061C patent/HUS1600061I1/hu unknown
- 2016-12-20 LT LTPA2016042C patent/LTPA2016042I1/lt unknown
-
2017
- 2017-11-21 NO NO2017063C patent/NO2017063I1/no unknown
- 2017-11-21 NO NO2017065C patent/NO2017065I1/no unknown
Also Published As
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HK1174922A1 (en) | Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-2,6-]]-2-]] | |
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