SK286749B6 - Aglomeráty ß-laktámového antibiotika, spôsob ich prípravy, zmes aglomerátov, použitie aglomerátov a tableta obsahujúca stlačené aglomeráty - Google Patents

Aglomeráty ß-laktámového antibiotika, spôsob ich prípravy, zmes aglomerátov, použitie aglomerátov a tableta obsahujúca stlačené aglomeráty Download PDF

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Publication number
SK286749B6
SK286749B6 SK1244-98A SK124498A SK286749B6 SK 286749 B6 SK286749 B6 SK 286749B6 SK 124498 A SK124498 A SK 124498A SK 286749 B6 SK286749 B6 SK 286749B6
Authority
SK
Slovakia
Prior art keywords
agglomerates
lactam antibiotic
additives
amoxicillin trihydrate
tablets
Prior art date
Application number
SK1244-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK124498A3 (en
Inventor
Johannes Raneburger
Erich Zeisl
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT47496A external-priority patent/AT407214B/de
Priority claimed from AT144596A external-priority patent/AT407701B/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SK124498A3 publication Critical patent/SK124498A3/sk
Publication of SK286749B6 publication Critical patent/SK286749B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SK1244-98A 1996-03-13 1997-03-13 Aglomeráty ß-laktámového antibiotika, spôsob ich prípravy, zmes aglomerátov, použitie aglomerátov a tableta obsahujúca stlačené aglomeráty SK286749B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT47496A AT407214B (de) 1996-03-13 1996-03-13 Verfahren zur herstellung von hilfsstoffefreien agglomeraten aus beta-lactamantibiotika
AT144596A AT407701B (de) 1996-08-12 1996-08-12 Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
PCT/EP1997/001269 WO1997033564A1 (fr) 1996-03-13 1997-03-13 Agglomerats renfermant des composes de betalactamines

Publications (2)

Publication Number Publication Date
SK124498A3 SK124498A3 (en) 1999-01-11
SK286749B6 true SK286749B6 (sk) 2009-04-06

Family

ID=25592858

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1244-98A SK286749B6 (sk) 1996-03-13 1997-03-13 Aglomeráty ß-laktámového antibiotika, spôsob ich prípravy, zmes aglomerátov, použitie aglomerátov a tableta obsahujúca stlačené aglomeráty

Country Status (21)

Country Link
US (1) US6440462B1 (fr)
EP (2) EP1283034A3 (fr)
JP (1) JP3822246B2 (fr)
KR (1) KR100468204B1 (fr)
CN (1) CN1160058C (fr)
AU (1) AU715682B2 (fr)
BR (1) BR9708316A (fr)
CA (1) CA2245094C (fr)
CZ (1) CZ298815B6 (fr)
ES (1) ES2193899T1 (fr)
HU (1) HUP9900983A3 (fr)
ID (1) ID16237A (fr)
IL (1) IL125492A0 (fr)
NO (1) NO326821B1 (fr)
NZ (1) NZ331178A (fr)
PL (1) PL187761B1 (fr)
RU (1) RU2195265C2 (fr)
SK (1) SK286749B6 (fr)
TR (1) TR199801824T2 (fr)
TW (1) TWI225402B (fr)
WO (1) WO1997033564A1 (fr)

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AT500134A1 (de) * 2002-02-01 2005-11-15 Sandoz Ag Verfahren zur herstellung eines entmischungsstabilen granulats
AT500132A1 (de) * 2002-02-06 2005-11-15 Sandoz Ag Organische verbindungen
EP1474104A2 (fr) * 2002-02-01 2004-11-10 Sandoz Ag Granulats stables a la segregation
AT500131A1 (de) * 2002-02-01 2005-11-15 Sandoz Ag Organische verbindungen
AT500133A1 (de) * 2002-02-06 2005-11-15 Sandoz Ag Verfahren zur herstellung eines entmischungsstabilen granulats
AU2003302381A1 (en) * 2002-11-26 2004-06-18 Lek Pharmaceuticals D.D. Pharmaceutical compositions comprising amoxicillin and clavulanic acid
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AU2004258949B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
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US8460710B2 (en) 2003-09-15 2013-06-11 Shionogi, Inc. Antibiotic product, use and formulation thereof
KR20070028469A (ko) * 2004-06-30 2007-03-12 디에스엠 아이피 어셋츠 비.브이. β-락탐 항생제를 포함하는 과립
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JP5227591B2 (ja) * 2005-01-07 2013-07-03 サンド・アクチエンゲゼルシヤフト アモキシシリンを含む粒剤の調製方法
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US10059722B2 (en) 2012-11-02 2018-08-28 University Of Kansas Cephalosporin derivatives and methods of use
US9820943B2 (en) * 2013-09-03 2017-11-21 Dsm Sinochem Pharmaceuticals Netherlands B.V. Micronized amoxicillin
KR101983170B1 (ko) * 2014-05-19 2019-05-28 삼성전기주식회사 모바일 기기용 저항 조립체 및 그 제조 방법
CN104473892B (zh) * 2014-12-25 2017-08-15 辰欣药业股份有限公司 一种用于直接压片的法罗培南钠组合物及其制备方法
CN107875136B (zh) * 2017-12-27 2021-03-05 广州白云山医药集团股份有限公司白云山制药总厂 一种阿莫西林药物制剂及其制备方法

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Also Published As

Publication number Publication date
CA2245094A1 (fr) 1997-09-18
PL187761B1 (pl) 2004-10-29
HUP9900983A2 (hu) 1999-08-30
PL328400A1 (en) 1999-01-18
NO983904D0 (no) 1998-08-25
KR100468204B1 (ko) 2005-06-17
JP2000501112A (ja) 2000-02-02
NO983904L (no) 1998-08-25
RU2195265C2 (ru) 2002-12-27
SK124498A3 (en) 1999-01-11
IL125492A0 (en) 1999-03-12
CN1213298A (zh) 1999-04-07
WO1997033564A1 (fr) 1997-09-18
NZ331178A (en) 2000-06-23
KR19990087104A (ko) 1999-12-15
ID16237A (id) 1997-09-11
ES2193899T1 (es) 2003-11-16
TR199801824T2 (xx) 1998-12-21
EP1283034A2 (fr) 2003-02-12
CZ291698A3 (cs) 1998-12-16
NO326821B1 (no) 2009-02-23
TWI225402B (en) 2004-12-21
AU2156097A (en) 1997-10-01
CA2245094C (fr) 2007-09-25
EP1283034A3 (fr) 2003-03-05
HUP9900983A3 (en) 1999-11-29
US6440462B1 (en) 2002-08-27
EP0896526A1 (fr) 1999-02-17
BR9708316A (pt) 1999-08-03
JP3822246B2 (ja) 2006-09-13
CZ298815B6 (cs) 2008-02-13
AU715682B2 (en) 2000-02-10
CN1160058C (zh) 2004-08-04

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Expiry date: 20170313