IL125492A0 - Agglomerates - Google Patents

Agglomerates

Info

Publication number
IL125492A0
IL125492A0 IL12549297A IL12549297A IL125492A0 IL 125492 A0 IL125492 A0 IL 125492A0 IL 12549297 A IL12549297 A IL 12549297A IL 12549297 A IL12549297 A IL 12549297A IL 125492 A0 IL125492 A0 IL 125492A0
Authority
IL
Israel
Prior art keywords
agglomerates
Prior art date
Application number
IL12549297A
Other languages
English (en)
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT47496A external-priority patent/AT407214B/de
Priority claimed from AT144596A external-priority patent/AT407701B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Publication of IL125492A0 publication Critical patent/IL125492A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
IL12549297A 1996-03-13 1997-03-13 Agglomerates IL125492A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT47496A AT407214B (de) 1996-03-13 1996-03-13 Verfahren zur herstellung von hilfsstoffefreien agglomeraten aus beta-lactamantibiotika
AT144596A AT407701B (de) 1996-08-12 1996-08-12 Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
PCT/EP1997/001269 WO1997033564A1 (en) 1996-03-13 1997-03-13 Agglomerates containing beta-lactam compounds

Publications (1)

Publication Number Publication Date
IL125492A0 true IL125492A0 (en) 1999-03-12

Family

ID=25592858

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12549297A IL125492A0 (en) 1996-03-13 1997-03-13 Agglomerates

Country Status (21)

Country Link
US (1) US6440462B1 (xx)
EP (2) EP0896526A1 (xx)
JP (1) JP3822246B2 (xx)
KR (1) KR100468204B1 (xx)
CN (1) CN1160058C (xx)
AU (1) AU715682B2 (xx)
BR (1) BR9708316A (xx)
CA (1) CA2245094C (xx)
CZ (1) CZ298815B6 (xx)
ES (1) ES2193899T1 (xx)
HU (1) HUP9900983A3 (xx)
ID (1) ID16237A (xx)
IL (1) IL125492A0 (xx)
NO (1) NO326821B1 (xx)
NZ (1) NZ331178A (xx)
PL (1) PL187761B1 (xx)
RU (1) RU2195265C2 (xx)
SK (1) SK286749B6 (xx)
TR (1) TR199801824T2 (xx)
TW (1) TWI225402B (xx)
WO (1) WO1997033564A1 (xx)

Families Citing this family (35)

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EP1023065A1 (en) * 1997-08-29 2000-08-02 Dsm N.V. Granules free of excipients
WO2000025751A2 (en) * 1998-10-30 2000-05-11 Fuisz International Ltd. Improved amoxycillin and clavulanate composition
US6177421B1 (en) * 1999-05-04 2001-01-23 Fuisz International Ltd. Amoxicillin and clavulanate composition
TR200102771T2 (tr) † 1999-04-01 2002-04-22 Dsm N. V. Kristalleştirme ile elde edilen aglomeralar
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6358526B1 (en) * 2000-08-16 2002-03-19 Rexall Sundown Method of making tablets and tablet compositions produced therefrom
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20040132712A1 (en) * 2001-04-12 2004-07-08 Otto Damon Pharmaceutical compositions comprising clavulanic acid
AT500131A1 (de) * 2002-02-01 2005-11-15 Sandoz Ag Organische verbindungen
AT500132A1 (de) * 2002-02-06 2005-11-15 Sandoz Ag Organische verbindungen
AT500134A1 (de) * 2002-02-01 2005-11-15 Sandoz Ag Verfahren zur herstellung eines entmischungsstabilen granulats
AU2003208358A1 (en) * 2002-02-01 2003-09-02 Sandoz Gmbh Demixing-stable granulate
AT500133A1 (de) * 2002-02-06 2005-11-15 Sandoz Ag Verfahren zur herstellung eines entmischungsstabilen granulats
EP1581191A1 (en) * 2002-11-26 2005-10-05 LEK Pharmaceuticals D.D. Pharmaceutical compositions comprising amoxicillin and clavulanic acid
CN1761457B (zh) * 2003-03-21 2010-05-12 帝斯曼知识产权资产管理有限公司 三水羟氨苄青霉素
US7534781B2 (en) 2003-03-21 2009-05-19 Dsm Ip Assets B.V. Crystalline amoxicillin trihydrate powder
KR101075700B1 (ko) * 2003-03-21 2011-10-21 디에스엠 아이피 어셋츠 비.브이. 아목시실린 트리하이드레이트
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8313775B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
US8313776B2 (en) 2003-07-21 2012-11-20 Shionogi Inc. Antibiotic product, use and formulation thereof
WO2005016311A1 (en) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Robust pellet
JP2007502294A (ja) 2003-08-12 2007-02-08 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
EP1658034A4 (en) * 2003-08-29 2011-06-22 Middlebrook Pharmaceuticals Inc ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION
JP2007513869A (ja) 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
BRPI0512933B8 (pt) * 2004-06-30 2021-05-25 Dsm Ip Assets Bv grânulos compactados por rolo compreendendo antibiótico de (beta) - lactama e processo para preparação dos ditos grânulos
JP2008505124A (ja) 2004-07-02 2008-02-21 アドバンシス ファーマスーティカル コーポレイション パルス送達用錠剤
WO2006072577A1 (en) * 2005-01-07 2006-07-13 Sandoz Ag Process for preparing granulates comprising amoxicillin
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
WO2014071283A1 (en) * 2012-11-02 2014-05-08 University Of Kansas Cephalosporin derivatives and methods of use
US9820943B2 (en) * 2013-09-03 2017-11-21 Dsm Sinochem Pharmaceuticals Netherlands B.V. Micronized amoxicillin
KR101983170B1 (ko) * 2014-05-19 2019-05-28 삼성전기주식회사 모바일 기기용 저항 조립체 및 그 제조 방법
CN104473892B (zh) * 2014-12-25 2017-08-15 辰欣药业股份有限公司 一种用于直接压片的法罗培南钠组合物及其制备方法
CN107875136B (zh) * 2017-12-27 2021-03-05 广州白云山医药集团股份有限公司白云山制药总厂 一种阿莫西林药物制剂及其制备方法

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CH434571A (de) * 1966-07-05 1967-04-30 Chemical And Pharmaceutical Pa Verfahren zur Herstellung von Antibiotika mit verlängerter therapeutischer Wirkung
GB1166958A (en) 1967-05-22 1969-10-15 Monsanto Chemicals Process for Making Tablets Containing Aspirin and Salicylamide
US3551457A (en) 1968-10-22 1970-12-29 Gen Mills Inc Free-flowing form of tocopheryl succinate
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
GB1520247A (en) 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
FR2282258A1 (fr) 1974-08-19 1976-03-19 Merck & Co Inc Procede de preparation de comprimes a forte teneur en chlorhydrate de d-(-)-alpha-aminobenzylpenicillinate de pivaloyloxymethyle
US4143129A (en) * 1975-10-11 1979-03-06 Lilly Industries Limited Cephalexin tablets
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DE3636209A1 (de) 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
US5288861A (en) * 1987-01-29 1994-02-22 Beecham Group Plc Potassium clavulanate in rosette form
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EP0330284B1 (en) * 1988-02-25 1994-07-27 Yamanouchi Europe B.V. Process for the preparation of a pharmaceutical granulate
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DE3927810A1 (de) * 1989-08-23 1991-02-28 Basf Ag Riboflavingranulate
DE3929864A1 (de) 1989-09-08 1991-03-14 Nordmark Arzneimittel Gmbh Verfahren zur herstellung von theophyllin-pellets
DE4014262A1 (de) 1990-05-04 1991-11-07 Basf Ag Gut rieselfaehige, nichtstaubende bindemittelfreie riboflavinspruehgranulate oder -mikrogranulate aus reinem riboflavin und ein verfahren zu deren herstellung
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FR2717387B1 (fr) 1994-03-17 1996-10-18 Hi Pharmtech Procédé de fabrication de comprimés à croquer à base de troxérutine, de carbonate de calcium, de phosphate de calcium, d'aspartate d'arginine, de glutamate d'arginine d'amoxicilline.
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Also Published As

Publication number Publication date
EP1283034A3 (en) 2003-03-05
PL328400A1 (en) 1999-01-18
CN1160058C (zh) 2004-08-04
US6440462B1 (en) 2002-08-27
HUP9900983A3 (en) 1999-11-29
BR9708316A (pt) 1999-08-03
JP2000501112A (ja) 2000-02-02
CA2245094A1 (en) 1997-09-18
TWI225402B (en) 2004-12-21
PL187761B1 (pl) 2004-10-29
NO326821B1 (no) 2009-02-23
TR199801824T2 (xx) 1998-12-21
NO983904D0 (no) 1998-08-25
EP1283034A2 (en) 2003-02-12
AU715682B2 (en) 2000-02-10
JP3822246B2 (ja) 2006-09-13
ID16237A (id) 1997-09-11
KR100468204B1 (ko) 2005-06-17
CZ291698A3 (cs) 1998-12-16
SK124498A3 (en) 1999-01-11
CZ298815B6 (cs) 2008-02-13
NO983904L (no) 1998-08-25
RU2195265C2 (ru) 2002-12-27
AU2156097A (en) 1997-10-01
KR19990087104A (ko) 1999-12-15
CA2245094C (en) 2007-09-25
NZ331178A (en) 2000-06-23
WO1997033564A1 (en) 1997-09-18
ES2193899T1 (es) 2003-11-16
CN1213298A (zh) 1999-04-07
SK286749B6 (sk) 2009-04-06
EP0896526A1 (en) 1999-02-17
HUP9900983A2 (hu) 1999-08-30

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