SK282512B6 - Dihydrát 4,10beta-diacetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1- hydroxy-9-oxo-19-nor-cyklopropa[g]tax-11-én-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenylpropionátu a spôsob jeho prípravy - Google Patents

Dihydrát 4,10beta-diacetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1- hydroxy-9-oxo-19-nor-cyklopropa[g]tax-11-én-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenylpropionátu a spôsob jeho prípravy Download PDF

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Publication number
SK282512B6
SK282512B6 SK790-98A SK79098A SK282512B6 SK 282512 B6 SK282512 B6 SK 282512B6 SK 79098 A SK79098 A SK 79098A SK 282512 B6 SK282512 B6 SK 282512B6
Authority
SK
Slovakia
Prior art keywords
hydroxy
cyclopropa
benzoyloxy
tax
oxo
Prior art date
Application number
SK790-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK79098A3 (en
Inventor
Eric Didier
Michel Lavigne
Jean-Ren Authelin
Original Assignee
Aventis Pharma S. A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Aventis Pharma S. A. filed Critical Aventis Pharma S. A.
Publication of SK79098A3 publication Critical patent/SK79098A3/sk
Publication of SK282512B6 publication Critical patent/SK282512B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SK790-98A 1995-12-14 1996-12-09 Dihydrát 4,10beta-diacetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1- hydroxy-9-oxo-19-nor-cyklopropa[g]tax-11-én-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenylpropionátu a spôsob jeho prípravy SK282512B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514841A FR2742438B1 (fr) 1995-12-14 1995-12-14 Dihydrate du (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy- 3-phenylpropionate de 4,10beta-diacetoxy-2alpha-benzoyloxy- 5beta,2o-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g)tax-11- ene-13alpha-yle, et son procede de preparation
PCT/FR1996/001957 WO1997021695A1 (fr) 1995-12-14 1996-12-09 DIHYDRATE DU (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4,10β-DIACETOXY-2α-BENZOYLOXY-5β,20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA[G]TAX-11-ENE-13α-YLE, ET SON PROCEDE DE PREPARATION

Publications (2)

Publication Number Publication Date
SK79098A3 SK79098A3 (en) 1998-11-04
SK282512B6 true SK282512B6 (sk) 2002-10-08

Family

ID=9485512

Family Applications (1)

Application Number Title Priority Date Filing Date
SK790-98A SK282512B6 (sk) 1995-12-14 1996-12-09 Dihydrát 4,10beta-diacetoxy-2alfa-benzoyloxy-5beta,20-epoxy-1- hydroxy-9-oxo-19-nor-cyklopropa[g]tax-11-én-13alfa-yl-(2R,3S)- 3-terc-butoxykarbonylamino-2-hydroxy-3-fenylpropionátu a spôsob jeho prípravy

Country Status (37)

Country Link
EP (1) EP0876361B1 (ja)
JP (1) JP4059351B2 (ja)
KR (1) KR100429330B1 (ja)
CN (1) CN101113143A (ja)
AR (1) AR004380A1 (ja)
AT (1) ATE204573T1 (ja)
AU (1) AU713086C (ja)
BG (1) BG63010B1 (ja)
BR (1) BR9611957A (ja)
CA (1) CA2236545C (ja)
CO (1) CO4810227A1 (ja)
CZ (1) CZ288998B6 (ja)
DE (1) DE69614716T2 (ja)
DK (1) DK0876361T3 (ja)
DZ (1) DZ2140A1 (ja)
EA (1) EA000668B1 (ja)
ES (1) ES2162123T3 (ja)
FR (1) FR2742438B1 (ja)
GR (1) GR3036437T3 (ja)
HU (1) HU224962B1 (ja)
IL (1) IL124766A (ja)
IN (1) IN185809B (ja)
MY (1) MY115886A (ja)
NO (1) NO317356B1 (ja)
NZ (1) NZ323964A (ja)
OA (1) OA11012A (ja)
PL (1) PL187613B1 (ja)
PT (1) PT876361E (ja)
RO (1) RO115880B1 (ja)
SK (1) SK282512B6 (ja)
TN (1) TNSN96157A1 (ja)
TR (1) TR199801087T2 (ja)
TW (1) TW358093B (ja)
UA (1) UA55401C2 (ja)
UY (1) UY24387A1 (ja)
WO (1) WO1997021695A1 (ja)
ZA (1) ZA9610200B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102851740A (zh) * 2011-06-30 2013-01-02 复旦大学 一种氟代多烯紫杉醇晶体及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
PL187613B1 (pl) 2004-08-31
DE69614716T2 (de) 2002-06-27
PL327451A1 (en) 1998-12-07
FR2742438B1 (fr) 1998-01-16
CA2236545A1 (fr) 1997-06-19
AU1101397A (en) 1997-07-03
NO982561L (no) 1998-06-04
NO317356B1 (no) 2004-10-18
EP0876361A1 (fr) 1998-11-11
CN101113143A (zh) 2008-01-30
JP4059351B2 (ja) 2008-03-12
MX9804604A (es) 1998-10-31
SK79098A3 (en) 1998-11-04
EA199800452A1 (ru) 1998-12-24
RO115880B1 (ro) 2000-07-28
BG63010B1 (bg) 2001-01-31
ZA9610200B (en) 1997-06-23
UY24387A1 (es) 2001-08-27
BG102535A (en) 1999-08-31
JP2000501722A (ja) 2000-02-15
MY115886A (en) 2003-09-30
CA2236545C (fr) 2007-01-30
OA11012A (fr) 2003-03-06
ATE204573T1 (de) 2001-09-15
AU713086B2 (en) 1999-11-25
AU713086C (en) 2002-09-19
DK0876361T3 (da) 2001-10-08
AR004380A1 (es) 1998-11-04
HU224962B1 (en) 2006-04-28
KR100429330B1 (ko) 2005-01-13
DZ2140A1 (fr) 2002-07-23
GR3036437T3 (en) 2001-11-30
EP0876361B1 (fr) 2001-08-22
NZ323964A (en) 2000-01-28
EA000668B1 (ru) 2000-02-28
BR9611957A (pt) 1999-02-17
CZ288998B6 (cs) 2001-10-17
ES2162123T3 (es) 2001-12-16
HUP9904048A3 (en) 2001-08-28
NO982561D0 (no) 1998-06-04
KR19990072107A (ko) 1999-09-27
UA55401C2 (uk) 2003-04-15
IL124766A (en) 2001-03-19
DE69614716D1 (de) 2001-09-27
CZ183098A3 (cs) 1998-09-16
IL124766A0 (en) 1999-01-26
IN185809B (ja) 2001-05-05
HUP9904048A1 (hu) 2001-04-28
TW358093B (en) 1999-05-11
TNSN96157A1 (fr) 2005-03-15
CO4810227A1 (es) 1999-06-30
WO1997021695A1 (fr) 1997-06-19
FR2742438A1 (fr) 1997-06-20
PT876361E (pt) 2001-11-30
TR199801087T2 (xx) 1998-09-21

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Legal Events

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20121209