DE69614716D1 - Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellung - Google Patents
Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellungInfo
- Publication number
- DE69614716D1 DE69614716D1 DE69614716T DE69614716T DE69614716D1 DE 69614716 D1 DE69614716 D1 DE 69614716D1 DE 69614716 T DE69614716 T DE 69614716T DE 69614716 T DE69614716 T DE 69614716T DE 69614716 D1 DE69614716 D1 DE 69614716D1
- Authority
- DE
- Germany
- Prior art keywords
- epoxx
- hydroxyo
- 13alpha
- 5beta
- 2alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- ZVAFCKLQJCZGAP-WDEREUQCSA-N (2r,3s)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoic acid Chemical compound CC(C)(C)OC(=O)N[C@H]([C@@H](O)C(O)=O)C1=CC=CC=C1 ZVAFCKLQJCZGAP-WDEREUQCSA-N 0.000 title 1
- 150000004683 dihydrates Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9514841A FR2742438B1 (fr) | 1995-12-14 | 1995-12-14 | Dihydrate du (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy- 3-phenylpropionate de 4,10beta-diacetoxy-2alpha-benzoyloxy- 5beta,2o-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g)tax-11- ene-13alpha-yle, et son procede de preparation |
| PCT/FR1996/001957 WO1997021695A1 (fr) | 1995-12-14 | 1996-12-09 | DIHYDRATE DU (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4,10β-DIACETOXY-2α-BENZOYLOXY-5β,20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA[G]TAX-11-ENE-13α-YLE, ET SON PROCEDE DE PREPARATION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69614716D1 true DE69614716D1 (de) | 2001-09-27 |
| DE69614716T2 DE69614716T2 (de) | 2002-06-27 |
Family
ID=9485512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69614716T Expired - Lifetime DE69614716T2 (de) | 1995-12-14 | 1996-12-09 | Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellung |
Country Status (37)
| Country | Link |
|---|---|
| EP (1) | EP0876361B1 (de) |
| JP (1) | JP4059351B2 (de) |
| KR (1) | KR100429330B1 (de) |
| CN (1) | CN101113143A (de) |
| AR (1) | AR004380A1 (de) |
| AT (1) | ATE204573T1 (de) |
| AU (1) | AU713086C (de) |
| BG (1) | BG63010B1 (de) |
| BR (1) | BR9611957A (de) |
| CA (1) | CA2236545C (de) |
| CO (1) | CO4810227A1 (de) |
| CZ (1) | CZ288998B6 (de) |
| DE (1) | DE69614716T2 (de) |
| DK (1) | DK0876361T3 (de) |
| DZ (1) | DZ2140A1 (de) |
| EA (1) | EA000668B1 (de) |
| ES (1) | ES2162123T3 (de) |
| FR (1) | FR2742438B1 (de) |
| GR (1) | GR3036437T3 (de) |
| HU (1) | HU224962B1 (de) |
| IL (1) | IL124766A (de) |
| IN (1) | IN185809B (de) |
| MY (1) | MY115886A (de) |
| NO (1) | NO317356B1 (de) |
| NZ (1) | NZ323964A (de) |
| OA (1) | OA11012A (de) |
| PL (1) | PL187613B1 (de) |
| PT (1) | PT876361E (de) |
| RO (1) | RO115880B1 (de) |
| SK (1) | SK282512B6 (de) |
| TN (1) | TNSN96157A1 (de) |
| TR (1) | TR199801087T2 (de) |
| TW (1) | TW358093B (de) |
| UA (1) | UA55401C2 (de) |
| UY (1) | UY24387A1 (de) |
| WO (1) | WO1997021695A1 (de) |
| ZA (1) | ZA9610200B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102851740A (zh) * | 2011-06-30 | 2013-01-02 | 复旦大学 | 一种氟代多烯紫杉醇晶体及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2698871B1 (fr) * | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
-
1995
- 1995-12-14 FR FR9514841A patent/FR2742438B1/fr not_active Expired - Fee Related
-
1996
- 1996-09-12 UA UA98063068A patent/UA55401C2/uk unknown
- 1996-12-02 UY UY24387A patent/UY24387A1/es not_active IP Right Cessation
- 1996-12-04 TW TW085114946A patent/TW358093B/zh not_active IP Right Cessation
- 1996-12-04 ZA ZA9610200A patent/ZA9610200B/xx unknown
- 1996-12-09 JP JP52179097A patent/JP4059351B2/ja not_active Expired - Fee Related
- 1996-12-09 SK SK790-98A patent/SK282512B6/sk not_active IP Right Cessation
- 1996-12-09 CA CA002236545A patent/CA2236545C/fr not_active Expired - Fee Related
- 1996-12-09 EA EA199800452A patent/EA000668B1/ru not_active IP Right Cessation
- 1996-12-09 KR KR10-1998-0704420A patent/KR100429330B1/ko not_active Expired - Fee Related
- 1996-12-09 BR BR9611957A patent/BR9611957A/pt not_active IP Right Cessation
- 1996-12-09 DZ DZ960185A patent/DZ2140A1/fr active
- 1996-12-09 ES ES96941720T patent/ES2162123T3/es not_active Expired - Lifetime
- 1996-12-09 PL PL96327451A patent/PL187613B1/pl not_active IP Right Cessation
- 1996-12-09 TR TR1998/01087T patent/TR199801087T2/xx unknown
- 1996-12-09 RO RO98-01069A patent/RO115880B1/ro unknown
- 1996-12-09 CN CNA2007101024535A patent/CN101113143A/zh active Pending
- 1996-12-09 IL IL12476696A patent/IL124766A/xx not_active IP Right Cessation
- 1996-12-09 CZ CZ19981830A patent/CZ288998B6/cs not_active IP Right Cessation
- 1996-12-09 DE DE69614716T patent/DE69614716T2/de not_active Expired - Lifetime
- 1996-12-09 PT PT96941720T patent/PT876361E/pt unknown
- 1996-12-09 EP EP96941720A patent/EP0876361B1/de not_active Expired - Lifetime
- 1996-12-09 NZ NZ323964A patent/NZ323964A/xx not_active IP Right Cessation
- 1996-12-09 WO PCT/FR1996/001957 patent/WO1997021695A1/fr not_active Ceased
- 1996-12-09 HU HU9904048A patent/HU224962B1/hu not_active IP Right Cessation
- 1996-12-09 AT AT96941720T patent/ATE204573T1/de active
- 1996-12-09 DK DK96941720T patent/DK0876361T3/da active
- 1996-12-09 AU AU11013/97A patent/AU713086C/en not_active Ceased
- 1996-12-12 IN IN2788DE1996 patent/IN185809B/en unknown
- 1996-12-13 AR ARP960105668A patent/AR004380A1/es active IP Right Grant
- 1996-12-13 CO CO96065734A patent/CO4810227A1/es unknown
- 1996-12-13 MY MYPI96005258A patent/MY115886A/en unknown
- 1996-12-13 TN TNTNSN96157A patent/TNSN96157A1/fr unknown
-
1998
- 1998-06-04 NO NO19982561A patent/NO317356B1/no not_active IP Right Cessation
- 1998-06-12 BG BG102535A patent/BG63010B1/bg unknown
- 1998-06-15 OA OA9800085A patent/OA11012A/fr unknown
-
2001
- 2001-08-23 GR GR20010400773T patent/GR3036437T3/el not_active IP Right Cessation
Also Published As
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| DE69614716D1 (de) | Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC |