DE69614716D1 - Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellung - Google Patents

Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellung

Info

Publication number
DE69614716D1
DE69614716D1 DE69614716T DE69614716T DE69614716D1 DE 69614716 D1 DE69614716 D1 DE 69614716D1 DE 69614716 T DE69614716 T DE 69614716T DE 69614716 T DE69614716 T DE 69614716T DE 69614716 D1 DE69614716 D1 DE 69614716D1
Authority
DE
Germany
Prior art keywords
epoxx
hydroxyo
13alpha
5beta
2alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69614716T
Other languages
English (en)
Other versions
DE69614716T2 (de
Inventor
Eric Didier
Michel Lavigne
Jean-Rene Authelin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9485512&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69614716(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE69614716D1 publication Critical patent/DE69614716D1/de
Application granted granted Critical
Publication of DE69614716T2 publication Critical patent/DE69614716T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
DE69614716T 1995-12-14 1996-12-09 Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellung Expired - Lifetime DE69614716T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514841A FR2742438B1 (fr) 1995-12-14 1995-12-14 Dihydrate du (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy- 3-phenylpropionate de 4,10beta-diacetoxy-2alpha-benzoyloxy- 5beta,2o-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g)tax-11- ene-13alpha-yle, et son procede de preparation
PCT/FR1996/001957 WO1997021695A1 (fr) 1995-12-14 1996-12-09 DIHYDRATE DU (2R,3S)-3-TERT-BUTOXYCARBONYLAMINO-2-HYDROXY-3-PHENYLPROPIONATE DE 4,10β-DIACETOXY-2α-BENZOYLOXY-5β,20-EPOXY-1-HYDROXY-9-OXO-19-NOR-CYCLOPROPA[G]TAX-11-ENE-13α-YLE, ET SON PROCEDE DE PREPARATION

Publications (2)

Publication Number Publication Date
DE69614716D1 true DE69614716D1 (de) 2001-09-27
DE69614716T2 DE69614716T2 (de) 2002-06-27

Family

ID=9485512

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69614716T Expired - Lifetime DE69614716T2 (de) 1995-12-14 1996-12-09 Dihydrat von (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenylpropionsäure ester von 4,10-beta-diacetoxy-2alpha-benzoyloxy-5beta, 20-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g]tax-11-en-13alpha-yl und verfahren zu ihrer herstellung

Country Status (37)

Country Link
EP (1) EP0876361B1 (de)
JP (1) JP4059351B2 (de)
KR (1) KR100429330B1 (de)
CN (1) CN101113143A (de)
AR (1) AR004380A1 (de)
AT (1) ATE204573T1 (de)
AU (1) AU713086C (de)
BG (1) BG63010B1 (de)
BR (1) BR9611957A (de)
CA (1) CA2236545C (de)
CO (1) CO4810227A1 (de)
CZ (1) CZ288998B6 (de)
DE (1) DE69614716T2 (de)
DK (1) DK0876361T3 (de)
DZ (1) DZ2140A1 (de)
EA (1) EA000668B1 (de)
ES (1) ES2162123T3 (de)
FR (1) FR2742438B1 (de)
GR (1) GR3036437T3 (de)
HU (1) HU224962B1 (de)
IL (1) IL124766A (de)
IN (1) IN185809B (de)
MY (1) MY115886A (de)
NO (1) NO317356B1 (de)
NZ (1) NZ323964A (de)
OA (1) OA11012A (de)
PL (1) PL187613B1 (de)
PT (1) PT876361E (de)
RO (1) RO115880B1 (de)
SK (1) SK282512B6 (de)
TN (1) TNSN96157A1 (de)
TR (1) TR199801087T2 (de)
TW (1) TW358093B (de)
UA (1) UA55401C2 (de)
UY (1) UY24387A1 (de)
WO (1) WO1997021695A1 (de)
ZA (1) ZA9610200B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102851740A (zh) * 2011-06-30 2013-01-02 复旦大学 一种氟代多烯紫杉醇晶体及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
AR004380A1 (es) 1998-11-04
MY115886A (en) 2003-09-30
CA2236545A1 (fr) 1997-06-19
NO982561L (no) 1998-06-04
NO317356B1 (no) 2004-10-18
DZ2140A1 (fr) 2002-07-23
GR3036437T3 (en) 2001-11-30
KR19990072107A (ko) 1999-09-27
HUP9904048A3 (en) 2001-08-28
FR2742438B1 (fr) 1998-01-16
EP0876361A1 (de) 1998-11-11
BR9611957A (pt) 1999-02-17
EA199800452A1 (ru) 1998-12-24
ZA9610200B (en) 1997-06-23
PL187613B1 (pl) 2004-08-31
CO4810227A1 (es) 1999-06-30
EA000668B1 (ru) 2000-02-28
CZ288998B6 (cs) 2001-10-17
NO982561D0 (no) 1998-06-04
AU713086B2 (en) 1999-11-25
AU713086C (en) 2002-09-19
BG63010B1 (bg) 2001-01-31
TNSN96157A1 (fr) 2005-03-15
DK0876361T3 (da) 2001-10-08
CZ183098A3 (cs) 1998-09-16
PL327451A1 (en) 1998-12-07
ATE204573T1 (de) 2001-09-15
NZ323964A (en) 2000-01-28
AU1101397A (en) 1997-07-03
IN185809B (de) 2001-05-05
FR2742438A1 (fr) 1997-06-20
MX9804604A (es) 1998-10-31
CN101113143A (zh) 2008-01-30
BG102535A (en) 1999-08-31
UY24387A1 (es) 2001-08-27
HU224962B1 (en) 2006-04-28
JP2000501722A (ja) 2000-02-15
SK282512B6 (sk) 2002-10-08
PT876361E (pt) 2001-11-30
ES2162123T3 (es) 2001-12-16
TR199801087T2 (xx) 1998-09-21
IL124766A0 (en) 1999-01-26
EP0876361B1 (de) 2001-08-22
WO1997021695A1 (fr) 1997-06-19
DE69614716T2 (de) 2002-06-27
IL124766A (en) 2001-03-19
JP4059351B2 (ja) 2008-03-12
CA2236545C (fr) 2007-01-30
HUP9904048A1 (hu) 2001-04-28
OA11012A (fr) 2003-03-06
UA55401C2 (uk) 2003-04-15
KR100429330B1 (ko) 2005-01-13
SK79098A3 (en) 1998-11-04
RO115880B1 (ro) 2000-07-28
TW358093B (en) 1999-05-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC